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Tlie_0568 Tlie_0568 Tlie_0567 Tlie_0567 Tlie_0566 Tlie_0566 Tlie_0561 Tlie_0561 kdsA kdsA kdsB kdsB Tlie_0555 Tlie_0555 Tlie_0554 Tlie_0554 Tlie_0553 Tlie_0553 Tlie_0551 Tlie_0551 Tlie_0550 Tlie_0550 fabZ fabZ Tlie_0548 Tlie_0548 Tlie_0547 Tlie_0547 Tlie_0411 Tlie_0411 Tlie_0406 Tlie_0406 Tlie_0395 Tlie_0395 psd psd Tlie_0375 Tlie_0375 gpsA gpsA Tlie_1885 Tlie_1885 Tlie_1867 Tlie_1867 Tlie_1810 Tlie_1810 Tlie_1783 Tlie_1783 Tlie_1711 Tlie_1711 Tlie_1679 Tlie_1679 Tlie_1663 Tlie_1663 Tlie_1567 Tlie_1567 Tlie_1506 Tlie_1506 Tlie_1504 Tlie_1504 plsY plsY Tlie_1331 Tlie_1331 Tlie_1286 Tlie_1286 Tlie_1285 Tlie_1285 ispE ispE Tlie_1127 Tlie_1127 plsX plsX fabH fabH Tlie_1102 Tlie_1102 acpP acpP Tlie_1099 Tlie_1099 Tlie_1050 Tlie_1050 dxr dxr ispG ispG Tlie_1011 Tlie_1011 dxs dxs Tlie_0978 Tlie_0978 acpS acpS ispH ispH Tlie_0850 Tlie_0850 Tlie_0810 Tlie_0810 glmU glmU Tlie_0615 Tlie_0615
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Tlie_0568PFAM: Glycosyltransferase family 9 (heptosyltransferase); COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: aco:Amico_1486 glycosyl transferase family 9; PFAM: glycosyl transferase family 9; SPTR: Lipopolysaccharide heptosyltransferase II. (332 aa)
Tlie_0567PFAM: Glycosyltransferase family 9 (heptosyltransferase); COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: gem:GM21_2231 glycosyl transferase family 9; PFAM: glycosyl transferase family 9; SPTR: Lipopolysaccharide heptosyltransferase. (387 aa)
Tlie_0566PFAM: Glycosyltransferase family 9 (heptosyltransferase); COGs: COG0859 ADP-heptose:LPS heptosyltransferase; InterPro IPR002201; KEGG: tai:Taci_1703 glycosyl transferase family 9; PFAM: glycosyl transferase family 9; SPTR: Putative lipopolysaccharide biosynthesis protein. (326 aa)
Tlie_0561Three-deoxy-D-manno-octulosonic-acid transferase domain-containing protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (400 aa)
kdsA2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I family; TIGRFAM: 3-deoxy-8-phosphooctulonate synthase; phospho-2-dehydro-3-deoxyheptonate aldolase; COGs: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; InterPro IPR006218: IPR006269; KEGG: aco:Amico_1494 2-dehydro-3-deoxyphosphooctonate aldolase; PFAM: DAHP synthetase I/KDSA; PRIAM: 3-deoxy-8-phosphooctulonate synthase; SPTR: 2-dehydro-3-deoxyphosphooctonate aldolase; TIGRFAM: 2-dehydro-3-deoxyphosphooctonate aldolase. (284 aa)
kdsB3-deoxy-D-manno- octulosonatecytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (247 aa)
Tlie_0555Hypothetical protein; PFAM: Lipid-A-disaccharide synthetase; COGs: COG0763 Lipid A disaccharide synthetase; KEGG: aco:Amico_1497 hypothetical protein; SPTR: Putative uncharacterized protein. (359 aa)
Tlie_0554lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (372 aa)
Tlie_0553PFAM: Protein of unknown function (DUF1009); COGs: COG3494 conserved hypothetical protein; InterPro IPR010415; KEGG: tai:Taci_1287 protein of unknown function DUF1009; PFAM: protein of unknown function DUF1009; SPTR: Putative uncharacterized protein. (267 aa)
Tlie_0551PFAM: haloacid dehalogenase-like hydrolase; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; COGs: COG1778 Low specificity phosphatase (HAD superfamily); InterPro IPR005834: IPR010023: IPR006549; KEGG: aco:Amico_1501 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; PFAM: Haloacid dehalogenase domain protein hydrolase; SPTR: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; TIGRFAM: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family; hydrolase, HAD-superfamily, subfamily IIIA. (161 aa)
Tlie_0550acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (270 aa)
fabZ3-hydroxyacyl-(acyl-carrier-protein) dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (146 aa)
Tlie_0548UDP-3-0-acyl N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis. Belongs to the LpxC family. (280 aa)
Tlie_0547UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; PFAM: Bacterial transferase hexapeptide (three repeats); TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; COGs: COG1044 UDP-3-O-(3-hydroxymyristoyl); InterPro IPR001451: IPR007691: IPR018357; KEGG: aco:Amico_1505 UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; SPTR: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; TIGRFAM: UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase. (348 aa)
Tlie_0411PFAM: Bacterial lipid A biosynthesis acyltransferase; COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: aco:Amico_0274 lipid A biosynthesis acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis acyltransferase. (298 aa)
Tlie_0406Biotin/lipoyl attachment domain-containing protein; PFAM: Biotin-requiring enzyme; COGs: COG0511 Biotin carboxyl carrier protein; InterPro IPR000089: IPR001882; KEGG: aco:Amico_0269 biotin/lipoyl attachment domain-containing protein; PFAM: biotin/lipoyl attachment domain-containing protein; SPTR: Biotin/lipoyl attachment domain-containing protein. (135 aa)
Tlie_0395PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--serine O-phosphatidyltransferase; COGs: COG1183 Phosphatidylserine synthase; InterPro IPR000462: IPR004533; KEGG: aco:Amico_0254 CDP-diacylglycerol/serineO-phosphatidyl transferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR: CDP-diacylglycerol/serineO-phosphatidyl transferase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (243 aa)
psdPhosphatidylserine decarboxylase related protein; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). (210 aa)
Tlie_0375PFAM: Enoyl-CoA hydratase/isomerase family; COGs: COG1024 Enoyl-CoA hydratase/carnithine racemase; InterPro IPR001753; KEGG: ank:AnaeK_2009 enoyl-CoA hydratase/isomerase; PFAM: Enoyl-CoA hydratase/isomerase; SPTR: Enoyl-CoA hydratase/isomerase. (262 aa)
gpsAPFAM: NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR011128: IPR006109: IPR006168; KEGG: aco:Amico_1622 glycerol-3-phosphate dehydrogenase (NAD(P)(+)); PFAM: NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa)
Tlie_1885PFAM: Glycosyl transferases group 1; Monogalactosyldiacylglycerol (MGDG) synthase; COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR009695: IPR001296; KEGG: tai:Taci_1764 monogalactosyldiacylglycerol synthase; PFAM: Monogalactosyldiacylglycerol synthase; glycosyl transferase group 1; SPTR: Putative monogalactosyldiacylglycerol synthase, domain protein. (382 aa)
Tlie_1867Lipopolysaccharide biosynthesis protein; PFAM: Chain length determinant protein; COGs: COG3206 Uncharacterized protein involved in exopolysaccharide biosynthesis; InterPro IPR003856; KEGG: aco:Amico_1712 lipopolysaccharide biosynthesis protein; PFAM: lipopolysaccharide biosynthesis protein; SPTR: Lipopolysaccharide biosynthesis protein. (392 aa)
Tlie_1810TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family; COGs: COG0110 Acetyltransferase (isoleucine patch superfamily); InterPro IPR020019: IPR001451; KEGG: tte:TTE0666 acetyltransferase; SPTR: Acetyltransferases (The isoleucine patch superfamily); TIGRFAM: sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family. (215 aa)
Tlie_1783PFAM: Acyl-ACP thioesterase; COGs: COG3884 Acyl-ACP thioesterase; InterPro IPR002864; KEGG: dat:HRM2_18760 acyl-acyl carrier protein thioesterase; PFAM: acyl-ACP thioesterase; SPTR: Acyl-acyl carrier protein thioesterase. (251 aa)
Tlie_1711PFAM: NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; COGs: COG0240 Glycerol-3-phosphate dehydrogenase; InterPro IPR011128: IPR003421; KEGG: aco:Amico_1803 NAD/NADP octopine/nopaline dehydrogenase; PFAM: NAD/NADP octopine/nopaline dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: NAD/NADP octopine/nopaline dehydrogenase. (360 aa)
Tlie_1679Citrate lyase subunit gamma; PFAM: Malonate decarboxylase delta subunit (MdcD); TIGRFAM: citrate lyase acyl carrier protein; InterPro IPR006495; KEGG: tai:Taci_0022 citrate lyase subunit gamma; SPTR: Citrate lyase subunit gamma. (99 aa)
Tlie_1663Phospholipase D/Transphosphatidylase; COGs: COG1502 Phosphatidylserine/phosphatidylglycerophosphate/ cardiolipin synthase; InterPro IPR001736; KEGG: mes:Meso_3886 cardiolipin synthetase 2; PFAM: phospholipase D/Transphosphatidylase; SMART: phospholipase D/Transphosphatidylase; SPTR: Phospholipase D/Transphosphatidylase. (480 aa)
Tlie_1567Citrate lyase acyl carrier protein; PFAM: Malonate decarboxylase delta subunit (MdcD); TIGRFAM: citrate lyase acyl carrier protein; InterPro IPR006495; KEGG: tai:Taci_1369 citrate lyase acyl carrier protein; SPTR: Citrate lyase acyl carrier protein. (89 aa)
Tlie_1506PFAM: NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain; NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; InterPro IPR011128: IPR003421; KEGG: aco:Amico_1250 NAD/NADP octopine/nopaline dehydrogenase; PFAM: NAD/NADP octopine/nopaline dehydrogenase; NAD-dependent glycerol-3-phosphate dehydrogenase domain protein; SPTR: Putative NAD/nadp octopine/nopaline dehydrogenase. (361 aa)
Tlie_1504PFAM: NAD/NADP octopine/nopaline dehydrogenase, alpha-helical domain; InterPro IPR003421; KEGG: aco:Amico_1250 NAD/NADP octopine/nopaline dehydrogenase; PFAM: NAD/NADP octopine/nopaline dehydrogenase; SPTR: NAD/NADP octopine/nopaline dehydrogenase. (195 aa)
plsYProtein of unknown function DUF205; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (198 aa)
Tlie_1331PFAM: CDP-alcohol phosphatidyltransferase; TIGRFAM: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; COGs: COG0558 Phosphatidylglycerophosphate synthase; InterPro IPR000462: IPR004570; KEGG: tai:Taci_0640 CDP-diacylglycerol/glycerol-3-phosphate3-phospha tidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; SPTR:CDP-diacylglycerol/glycerol-3-phosphate3-phosp hatidyltransferase; TIGRFAM: CDP-diacylglycerol/glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (179 aa)
Tlie_1286Betaine reductase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; KEGG: tai:Taci_1135 betaine reductase; SPTR: Betaine reductase. (512 aa)
Tlie_1285PFAM: Fatty acid synthesis protein; COGs: COG0416 Fatty acid/phospholipid biosynthesis enzyme; InterPro IPR003664: IPR012116; KEGG: aco:Amico_1391 fatty acid synthesis PlsX protein; PFAM: fatty acid synthesis plsX protein; SPTR: Fatty acid synthesis plsX protein. (383 aa)
ispEGHMP kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (286 aa)
Tlie_1127PFAM: Acyltransferase; TIGRFAM: 1-acyl-sn-glycerol-3-phosphate acyltransferases; COGs: COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase; InterPro IPR002123; KEGG: aco:Amico_1088 phospholipid/glycerol acyltransferase; PFAM: phospholipid/glycerol acyltransferase; SMART: phospholipid/glycerol acyltransferase; SPTR: Phospholipid/glycerol acyltransferase. (216 aa)
plsXFatty acid/phospholipid synthesis protein PlsX; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (332 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (330 aa)
Tlie_1102(Acyl-carrier-protein) S-malonyltransferase; PFAM: Acyl transferase domain; TIGRFAM: malonyl CoA-acyl carrier protein transacylase; COGs: COG0331 (acyl-carrier-protein) S-malonyltransferase; InterPro IPR004410: IPR014043; KEGG: tai:Taci_1098 malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; SPTR: Malonyl CoA-acyl carrier protein transacylase; TIGRFAM: malonyl CoA-acyl carrier protein transacylase. (315 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (83 aa)
Tlie_10993-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (414 aa)
Tlie_1050PFAM: Cytidylyltransferase family; COGs: COG0575 CDP-diglyceride synthetase; InterPro IPR000374; KEGG: aco:Amico_0874 phosphatidate cytidylyltransferase; PFAM: phosphatidate cytidylyltransferase; SPTR: Phosphatidate cytidylyltransferase; Belongs to the CDS family. (272 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (380 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (352 aa)
Tlie_1011PFAM: Polyprenyl synthetase; COGs: COG0142 Geranylgeranyl pyrophosphate synthase; InterPro IPR000092; KEGG: aco:Amico_0851 geranyltranstransferase; PFAM: Polyprenyl synthetase; SPTR: Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (303 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (621 aa)
Tlie_0978Undecaprenyldiphospho-muramoylpentapeptidebeta-N -acetylglucosaminyltransferase; PFAM: Glycosyltransferase family 28 N-terminal domain; Glycosyltransferase family 28 C-terminal domain; COGs: COG0707 UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; InterPro IPR004276: IPR007235; KEGG: aco:Amico_0819 undecaprenyldiphospho-muramoylpentapeptidebeta-N -acetylglucosaminyltransferase; PFAM: Glycosyltransferase 28 domain; glycosyl transferase family 28; PRIAM: Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; SPTR: Putative UDP-N-acetylglucosamine--N- [...] (369 aa)
acpSHolo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (124 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (289 aa)
Tlie_0850PFAM: Phosphatidylglycerophosphatase A; COGs: COG1267 Phosphatidylglycerophosphatase A and related protein; InterPro IPR007686; KEGG: aco:Amico_0391 phosphatidylglycerophosphatase A; PFAM: phosphatidylglycerophosphatase A; SPTR: Phosphatidylglycerophosphatase A. (149 aa)
Tlie_0810PFAM: Bacterial lipid A biosynthesis acyltransferase; COGs: COG1560 Lauroyl/myristoyl acyltransferase; InterPro IPR004960; KEGG: aco:Amico_0413 lipid A biosynthesis acyltransferase; PFAM: lipid A biosynthesis acyltransferase; SPTR: Lipid A biosynthesis acyltransferase. (282 aa)
glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (464 aa)
Tlie_0615PFAM: Protein of unknown function (DUF1049); KEGG: aco:Amico_0595 hypothetical protein; SPTR: Putative uncharacterized protein. (130 aa)
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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