STRINGSTRING
Tlie_0815 Tlie_0815 kynU kynU Tlie_0162 Tlie_0162 Tlie_0167 Tlie_0167 Tlie_0185 Tlie_0185 Tlie_0286 Tlie_0286 Tlie_0383 Tlie_0383 Tlie_0423 Tlie_0423 Tlie_0500 Tlie_0500 iscS iscS Tlie_0563 Tlie_0563 Tlie_0683 Tlie_0683 Tlie_1883 Tlie_1883 Tlie_1809 Tlie_1809 hisC-2 hisC-2 glyA-2 glyA-2 Tlie_1699 Tlie_1699 Tlie_1661 Tlie_1661 Tlie_1660 Tlie_1660 Tlie_1507 Tlie_1507 glyA glyA Tlie_1476 Tlie_1476 Tlie_1472 Tlie_1472 Tlie_1338 Tlie_1338 Tlie_1330 Tlie_1330 Tlie_1314 Tlie_1314 Tlie_1313 Tlie_1313 Tlie_1179 Tlie_1179 Tlie_1164 Tlie_1164 Tlie_1160 Tlie_1160 selA selA hisC hisC Tlie_0842 Tlie_0842 Tlie_0838 Tlie_0838 Tlie_0837 Tlie_0837 Tlie_0813 Tlie_0813
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
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a 3D structure is known or predicted
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Your Input:
Tlie_0815PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192; KEGG: tai:Taci_0909 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V. (382 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (429 aa)
Tlie_0162PFAM: Aminotransferase class I and II; TIGRFAM: L-threonine-O-3-phosphate decarboxylase; histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR001176: IPR005860: IPR004839; KEGG: tjr:TherJR_1312 L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; SPTR: L-threonine-O-3-phosphate decarboxylase; TIGRFAM: L-threonine-O-3-phosphate decarboxylase. (367 aa)
Tlie_0167O-acetylhomoserine sulfhydrolase; PFAM: Cys/Met metabolism PLP-dependent enzyme; TIGRFAM: OAH/OAS sulfhydrylase; COGs: COG2873 O-acetylhomoserine sulfhydrylase; InterPro IPR006235: IPR000277; KEGG: tai:Taci_1506 O-acetylhomoserineaminocarboxypropyltransferase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; PRIAM: Cysteine synthase; SPTR: O-acetylhomoserine aminocarboxypropyltransferase; TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase. (439 aa)
Tlie_0185PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR004839; KEGG: cth:Cthe_0363 aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate/tyrosine/aromatic aminotransferase. (385 aa)
Tlie_0286PFAM: Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004838: IPR004839; KEGG: tsi:TSIB_1557 hypothetical protein; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II. (370 aa)
Tlie_0383LL-diaminopimelate aminotransferase apoenzyme; PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR004838; KEGG: pth:PTH_1308 aspartate/tyrosine/aromatic aminotransferase; PFAM: aminotransferase class I and II; SPTR: Aspartate/tyrosine/aromatic aminotransferase. (394 aa)
Tlie_0423L-threonine aldolase; PFAM: Beta-eliminating lyase; COGs: COG2008 Threonine aldolase; InterPro IPR001597; KEGG: aco:Amico_0290 threonine aldolase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Threonine aldolase; SPTR: Threonine aldolase. (344 aa)
Tlie_0500Alanine-glyoxylate aminotransferase apoenzyme; PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192: IPR020578; KEGG: bts:Btus_1044 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V. (391 aa)
iscSCysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. (392 aa)
Tlie_0563Glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tai:Taci_1278 glutamine--scyllo-inositol transaminase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; PRIAM: Glutamine--scyllo-inositol transaminase; SPTR: Glutamine--scyllo-inositol transaminase; Belongs to the DegT/DnrJ/EryC1 family. (403 aa)
Tlie_0683PFAM: Aminotransferase class-III; TIGRFAM: L-lysine 6-transaminase; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814: IPR017657; KEGG: tai:Taci_1141 L-lysine 6-transaminase; PFAM: aminotransferase class-III; SPTR: L-lysine 6-transaminase; TIGRFAM: L-lysine 6-transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (456 aa)
Tlie_1883PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein; COGs: COG0520 Selenocysteine lyase; InterPro IPR000192: IPR010969; KEGG: aco:Amico_1909 cysteine desulfurase family protein; PFAM: aminotransferase class V; SPTR: Cysteine desulfurase family protein; TIGRFAM: cysteine desulfurase family protein. (385 aa)
Tlie_1809PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: slp:Slip_0175 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (383 aa)
hisC-2PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR001917; KEGG: nth:Nther_1931 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (376 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (420 aa)
Tlie_1699PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: pab:PAB0086 pyridoxal phosphate-dependent aminotransferase; PFAM: aminotransferase class-III; SPTR: Pyridoxal phosphate-dependent aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
Tlie_1661Putative transcriptional regulator, GntR family; PFAM: Aminotransferase class I and II; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: aco:Amico_0227 putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; SPTR: Aminotransferase, class I and II family protein. (410 aa)
Tlie_1660PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839: IPR001176: IPR004838; KEGG: bbe:BBR47_45340 transaminase; PFAM: aminotransferase class I and II; SPTR: Putative aminotransferase. (383 aa)
Tlie_1507PFAM: Cys/Met metabolism PLP-dependent enzyme; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: gtn:GTNG_2270 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase. (395 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (421 aa)
Tlie_1476PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dba:Dbac_2014 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II. (398 aa)
Tlie_1472PFAM: Aminotransferase class-III; COGs: COG4992 Ornithine/acetylornithine aminotransferase; InterPro IPR005814; KEGG: tai:Taci_0450 aminotransferase class-III; PFAM: aminotransferase class-III; SPTR: Acetylornithine transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (374 aa)
Tlie_1338Pyridoxal phosphate-dependent acyltransferase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (396 aa)
Tlie_1330Tryptophanase; PFAM: Beta-eliminating lyase; COGs: COG3033 Tryptophanase; InterPro IPR001597: IPR011166; KEGG: tai:Taci_0642 tryptophanase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; PRIAM: Tryptophanase; SPTR: Tryptophanase. (463 aa)
Tlie_1314Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. (463 aa)
Tlie_1313PFAM: Aminotransferase class-V; COGs: COG1003 Glycine cleavage system protein P (pyridoxal-binding) C-terminal domain; InterPro IPR000192; KEGG: aco:Amico_1756 glycine dehydrogenase subunit 2; PFAM: aminotransferase class V; SPTR: Glycine dehydrogenase subunit 2. (529 aa)
Tlie_1179PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR001176: IPR004839; KEGG: aco:Amico_1183 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II. (396 aa)
Tlie_1164PFAM: Cys/Met metabolism PLP-dependent enzyme; COGs: COG0626 Cystathionine beta-lyase/cystathionine gamma-synthase; InterPro IPR000277; KEGG: tpd:Teth39_0897 cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; SPTR: Cystathionine gamma-synthase. (395 aa)
Tlie_1160PFAM: Aminotransferase class-V; TIGRFAM: cysteine desulfurase family protein, VC1184 subfamily; COGs: COG0520 Selenocysteine lyase; InterPro IPR011340: IPR000192; KEGG: rrs:RoseRS_3113 cysteine desulfurase family protein; PFAM: aminotransferase class V; PRIAM: Cysteine desulfurase; SPTR: Cysteine desulfurase family protein; TIGRFAM: cysteine desulfurase family protein. (414 aa)
selAL-seryl-tRNA(Sec) selenium transferase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (466 aa)
hisCPFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR001176: IPR005861: IPR004839; KEGG: tai:Taci_0938 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate transaminase; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)
Tlie_0842PFAM: DegT/DnrJ/EryC1/StrS aminotransferase family; COGs: COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; InterPro IPR000653; KEGG: tai:Taci_1668 DegT/DnrJ/EryC1/StrS aminotransferase; PFAM: DegT/DnrJ/EryC1/StrS aminotransferase; SPTR: DegT/DnrJ/EryC1/StrS aminotransferase; Belongs to the DegT/DnrJ/EryC1 family. (376 aa)
Tlie_0838PFAM: Aminotransferase class I and II; Bacterial regulatory proteins, gntR family; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR000524: IPR004839; KEGG: aco:Amico_0380 transcriptional regulator, GntR family with aminotransferase domain; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; SMART: regulatory protein GntR HTH; SPTR: Transcriptional regulator, GntR family. (463 aa)
Tlie_0837PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR001917: IPR004839; KEGG: aco:Amico_1039 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate transaminase. (362 aa)
Tlie_0813Putative transcriptional regulator, GntR family; PFAM: Aminotransferase class I and II; COGs: COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs; InterPro IPR004839; KEGG: tai:Taci_0315 putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; SPTR: Aminotransferase, class I and II family protein. (401 aa)
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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