STRINGSTRING
Tlie_0020 Tlie_0020 glsA glsA Tlie_0415 Tlie_0415 Tlie_0500 Tlie_0500 argH argH glmS glmS Tlie_0822 Tlie_0822 Tlie_0998 Tlie_0998 Tlie_1078 Tlie_1078 pyrB pyrB purQ purQ purF purF Tlie_1157 Tlie_1157 argG argG Tlie_1179 Tlie_1179 Tlie_1262 Tlie_1262 carA carA Tlie_1282 Tlie_1282 Tlie_1318 Tlie_1318 purA purA Tlie_1431 Tlie_1431 Tlie_1476 Tlie_1476 Tlie_1699 Tlie_1699 Tlie_1754 Tlie_1754
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Tlie_0020PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: aspartate racemase; COGs: COG1794 Aspartate racemase; InterPro IPR004380: IPR018187: IPR015942; KEGG: gbm:Gbem_1222 aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Aspartate racemase; TIGRFAM: aspartate racemase; Belongs to the aspartate/glutamate racemases family. (231 aa)
glsAL-glutaminase; PFAM: Glutaminase; TIGRFAM: glutaminase A; COGs: COG2066 Glutaminase; InterPro IPR015868; KEGG: tai:Taci_0795 glutaminase; PFAM: Glutaminase, core; PRIAM: Glutaminase; SPTR: Glutaminase; TIGRFAM: Glutaminase, core; Belongs to the glutaminase family. (305 aa)
Tlie_0415PFAM: Asp/Glu/Hydantoin racemase; TIGRFAM: aspartate racemase; COGs: COG1794 Aspartate racemase; InterPro IPR015942: IPR004380: IPR018187; KEGG: aco:Amico_1686 aspartate racemase; PFAM: Asp/Glu/hydantoin racemase; SPTR: Aspartate racemase; TIGRFAM: aspartate racemase. (231 aa)
Tlie_0500Alanine-glyoxylate aminotransferase apoenzyme; PFAM: Aminotransferase class-V; COGs: COG0075 Serine-pyruvate aminotransferase/ aspartate aminotransferase; InterPro IPR000192: IPR020578; KEGG: bts:Btus_1044 aminotransferase class V; PFAM: aminotransferase class V; SPTR: Aminotransferase class V. (391 aa)
argHPFAM: Lyase; TIGRFAM: argininosuccinate lyase; COGs: COG0165 Argininosuccinate lyase; InterPro IPR000362: IPR009049: IPR020557: IPR003031; KEGG: aco:Amico_1512 argininosuccinate lyase; PFAM: fumarate lyase; PRIAM: Argininosuccinate lyase; SPTR: Argininosuccinate lyase; TIGRFAM: argininosuccinate lyase. (469 aa)
glmSGlutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (610 aa)
Tlie_0822PFAM: Glutamate/Leucine/Phenylalanine/Valine dehydrogenase; Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; COGs: COG0334 Glutamate dehydrogenase/leucine dehydrogenase; InterPro IPR014362: IPR006095: IPR006097: IPR006096; KEGG: mvn:Mevan_1556 glutamate dehydrogenase; PFAM: Glu/Leu/Phe/Val dehydrogenase; Glu/Leu/Phe/Val dehydrogenase dimerisation region; PRIAM: Glutamate dehydrogenase (NADP(+)); SPTR: Glutamate dehydrogenase (NADP(+)); Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (448 aa)
Tlie_0998PFAM: Asparaginase; TIGRFAM: L-asparaginases, type I; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR020827: IPR006034: IPR006033; KEGG: pab:PAB2294 asparaginase related protein; PFAM: Asparaginase/glutaminase; SPTR: AsnA-1 L-asparaginase; TIGRFAM: L-asparaginase, type I. (342 aa)
Tlie_1078PFAM: Lyase; Adenylosuccinate lyase C-terminus; TIGRFAM: adenylosuccinate lyase; COGs: COG0015 Adenylosuccinate lyase; InterProIPR020557: IPR000362: IPR003031: IPR004769: IPR 019468; KEGG: aco:Amico_1048 adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; SPTR: Adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (436 aa)
pyrBPFAM: Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; TIGRFAM: aspartate carbamoyltransferase; COGs: COG0540 Aspartate carbamoyltransferase catalytic chain; InterPro IPR006130: IPR002082: IPR006132: IPR006131; KEGG: tai:Taci_1092 aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; PRIAM: Aspartate carbamoyltransferase; SPTR: Aspartate carbamoyltransferase; TIGRFAM: aspartate carbam [...] (308 aa)
purQPhosphoribosylformylglycinamidine synthase subunit I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to [...] (235 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (460 aa)
Tlie_1157PFAM: Ornithine cyclodeaminase/mu-crystallin family; TIGRFAM: alanine dehydrogenase, Archaeoglobus fulgidus type; COGs: COG2423 ornithine cyclodeaminase mu-crystallin homolog; InterPro IPR003462; KEGG: bbe:BBR47_45350 ornithine cyclodeaminase/mu-crystallin family protein; PFAM: ornithine cyclodeaminase/mu-crystallin; PRIAM: Ornithine cyclodeaminase; SPTR: Alanine dehydrogenase. (331 aa)
argGPFAM: Arginosuccinate synthase; TIGRFAM: argininosuccinate synthase; COGs: COG0137 Argininosuccinate synthase; InterPro IPR018223: IPR001518; KEGG: tai:Taci_0753 argininosuccinate synthase; PFAM: argininosuccinate synthase; PRIAM: Argininosuccinate synthase; SPTR: Argininosuccinate synthase; TIGRFAM: argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (413 aa)
Tlie_1179PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004838: IPR001176: IPR004839; KEGG: aco:Amico_1183 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II. (396 aa)
Tlie_1262Carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain, ATP binding domain; MGS-like domain; Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Carbamoyl-phosphate synthase L chain, N-terminal domain; TIGRFAM: carbamoyl-phosphate synthase, large subunit; COGs: COG0458 Carbamoylphosphate synthase large subunit (split gene in MJ); InterProIPR005483: IPR005479: IPR005481: IPR005480: IPR 011607: IPR011761: IPR006275; KEGG: adg:Adeg_0373 carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carb [...] (1050 aa)
carAPFAM: Carbamoyl-phosphate synthase small chain, CPSase domain; Glutamine amidotransferase class-I; TIGRFAM: carbamoyl-phosphate synthase, small subunit; COGs: COG0505 Carbamoylphosphate synthase small subunit; InterProIPR001317: IPR011702: IPR006220: IPR002474: IPR 000991: IPR017926: IPR006274; KEGG: cth:Cthe_0950 carbamoyl-phosphate synthase small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; SPTR: Carbamoyl-phosphate synthase, small subunit; TIGRFAM: carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (348 aa)
Tlie_1282PFAM: Alanine dehydrogenase/PNT, C-terminal domain; Alanine dehydrogenase/PNT, N-terminal domain; TIGRFAM: alanine dehydrogenase; COGs: COG0686 Alanine dehydrogenase; InterPro IPR007886: IPR007698: IPR008141; KEGG: tai:Taci_1131 alanine dehydrogenase; PFAM: alanine dehydrogenase/PNT domain protein; SPTR: Alanine dehydrogenase; TIGRFAM: alanine dehydrogenase; Belongs to the AlaDH/PNT family. (371 aa)
Tlie_1318PFAM: Glutamine synthetase, catalytic domain; Glutamine synthetase type III N terminal; COGs: COG3968 Uncharacterized protein related to glutamine synthetase; InterPro IPR008146; KEGG: aco:Amico_1415 glutamine synthetase catalytic region; PFAM: glutamine synthetase catalytic region; SPTR: Glutamine synthetase catalytic region. (703 aa)
purAAdenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa)
Tlie_1431Asparaginase/glutaminase; PFAM: Asparaginase; COGs: COG0252 L-asparaginase/ Glu-tRNAGln amidotransferase subunit D; InterPro IPR006034; KEGG: aco:Amico_0548 asparaginase/glutaminase; PFAM: Asparaginase/glutaminase; SPTR: Asparaginase/glutaminase. (329 aa)
Tlie_1476PFAM: Aminotransferase class I and II; COGs: COG0436 Aspartate/tyrosine/aromatic aminotransferase; InterPro IPR004839; KEGG: dba:Dbac_2014 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II. (398 aa)
Tlie_1699PFAM: Aminotransferase class-III; TIGRFAM: 4-aminobutyrate aminotransferase, prokaryotic type; COGs: COG0160 4-aminobutyrate aminotransferase and related aminotransferase; InterPro IPR005814; KEGG: pab:PAB0086 pyridoxal phosphate-dependent aminotransferase; PFAM: aminotransferase class-III; SPTR: Pyridoxal phosphate-dependent aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (463 aa)
Tlie_1754PFAM: Ornithine cyclodeaminase/mu-crystallin family; COGs: COG2423 ornithine cyclodeaminase mu-crystallin homolog; InterPro IPR003462; KEGG: aco:Amico_0921 ornithine cyclodeaminase; PFAM: ornithine cyclodeaminase/mu-crystallin; PRIAM: Ornithine cyclodeaminase; SPTR: Putative ornithine cyclodeaminase. (327 aa)
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.