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Tlie_0286 Tlie_0286 Tlie_0369 Tlie_0369 hutU hutU hutI hutI Tlie_0373 Tlie_0373 hisI hisI hisF hisF hisA hisA hisH hisH hisB hisB hisG hisG Tlie_0835 Tlie_0835 hisD hisD Tlie_0837 Tlie_0837 hutH hutH hisC hisC hisC-2 hisC-2
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene co-occurrence
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co-expression
protein homology
Your Input:
Tlie_0286PFAM: Aminotransferase class I and II; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR004838: IPR004839; KEGG: tsi:TSIB_1557 hypothetical protein; PFAM: aminotransferase class I and II; SPTR: Aminotransferase class I and II. (370 aa)
Tlie_0369Arginase/agmatinase/formiminoglutamase; PFAM: Arginase family; TIGRFAM: formimidoylglutamase; COGs: COG0010 Arginase/agmatinase/formimionoglutamate hydrolase arginase family; InterPro IPR006035; KEGG: tai:Taci_0232 arginase/agmatinase/formiminoglutamase; PFAM: Arginase/agmatinase/formiminoglutamase; SPTR: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family. (329 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (678 aa)
hutIImidazolonepropionase; PFAM: Amidohydrolase family; TIGRFAM: imidazolonepropionase; COGs: COG1228 Imidazolonepropionase and related amidohydrolase; InterPro IPR006680: IPR005920; KEGG: aco:Amico_1885 imidazolonepropionase; PFAM: amidohydrolase; SPTR: Imidazolonepropionase; TIGRFAM: imidazolonepropionase. (414 aa)
Tlie_0373PFAM: Formiminotransferase domain, N-terminal subdomain; Formiminotransferase domain; TIGRFAM: glutamate formiminotransferase; COGs: COG3643 Glutamate formiminotransferase; InterPro IPR012886: IPR013802: IPR004227; KEGG: tai:Taci_0915 glutamate formiminotransferase; PFAM: Formiminotransferase domain protein; Formiminotransferase domain protein; PRIAM: Glutamate formimidoyltransferase; SPTR: Glutamate formiminotransferase; TIGRFAM: glutamate formiminotransferase. (305 aa)
hisIPFAM: Phosphoribosyl-ATP pyrophosphohydrolase; Phosphoribosyl-AMP cyclohydrolase; TIGRFAM: phosphoribosyl-ATP pyrophosphohydrolase; COGs: COG0139 Phosphoribosyl-AMP cyclohydrolase; InterPro IPR002496: IPR008179: IPR021130; KEGG: aco:Amico_0677 phosphoribosyl-ATP diphosphatase; PFAM: phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphohydrolase-like; SPTR: Phosphoribosyl-ATP diphosphatase; TIGRFAM: phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family. (213 aa)
hisFImidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (263 aa)
hisA1-(5-phosphoribosyl)-5-((5- phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase; PFAM: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; COGs: COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase; InterPro IPR006062: IPR006063; KEGG: aco:Amico_0679 histidine biosynthesis protein; PFAM: histidine biosynthesis protein; SPTR: Histidine biosynthesis protein; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase. (240 aa)
hisHImidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (203 aa)
hisBPFAM: Imidazoleglycerol-phosphate dehydratase; COGs: COG0131 Imidazoleglycerol-phosphate dehydratase; InterPro IPR000807: IPR020565; KEGG: aco:Amico_0681 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase; PRIAM: Imidazoleglycerol-phosphate dehydratase; SPTR: Imidazoleglycerol-phosphate dehydratase. (189 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (214 aa)
Tlie_0835histidyl-tRNA synthetase 2; COGs: COG3705 ATP phosphoribosyltransferase involved in histidine biosynthesis; InterPro IPR004516; KEGG: aco:Amico_0683 histidyl-tRNA synthetase 2; SPTR: Histidyl-tRNA synthetase 2. (402 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (419 aa)
Tlie_0837PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR001917: IPR004839; KEGG: aco:Amico_1039 aminotransferase class I and II; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate transaminase. (362 aa)
hutHPFAM: Phenylalanine and histidine ammonia-lyase; TIGRFAM: phenylalanine ammonia-lyase; histidine ammonia-lyase; COGs: COG2986 Histidine ammonia-lyase; InterPro IPR001106: IPR005921; KEGG: tai:Taci_0916 histidine ammonia-lyase; PFAM: phenylalanine/histidine ammonia-lyase; PRIAM: Histidine ammonia-lyase; SPTR: Histidine ammonia-lyase; TIGRFAM: histidine ammonia-lyase. (509 aa)
hisCPFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR001176: IPR005861: IPR004839; KEGG: tai:Taci_0938 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate transaminase; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (369 aa)
hisC-2PFAM: Aminotransferase class I and II; TIGRFAM: histidinol-phosphate aminotransferase; COGs: COG0079 Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase; InterPro IPR005861: IPR004839: IPR001917; KEGG: nth:Nther_1931 histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; SPTR: Histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (376 aa)
Your Current Organism:
Thermovirga lienii
NCBI taxonomy Id: 580340
Other names: T. lienii DSM 17291, Thermovirga lienii DSM 17291, Thermovirga lienii str. DSM 17291, Thermovirga lienii strain DSM 17291
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