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pyrF pyrF Mmol_0313 Mmol_0313 hisA hisA hisF hisF trpF trpF trpA trpA Mmol_1336 Mmol_1336 Mmol_1338 Mmol_1338 Mmol_2239 Mmol_2239 trpC trpC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pyrFOrotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (240 aa)
Mmol_0313PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mfa:Mfla_0250 hexulose-6-phosphate synthase. (220 aa)
hisATIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein; KEGG: mfa:Mfla_0253 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (246 aa)
hisFImidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (255 aa)
trpFPFAM: N-(5'phosphoribosyl)anthranilate isomerase (PRAI); KEGG: pfs:PFLU4188 putative N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family. (204 aa)
trpATryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (266 aa)
Mmol_1336PFAM: histidine biosynthesis protein; KEGG: mfa:Mfla_1651 histidine biosynthesis; Belongs to the HisA/HisF family. (254 aa)
Mmol_1338PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mfa:Mfla_1654 orotidine 5'-phosphate decarboxylase. (210 aa)
Mmol_2239KEGG: mfa:Mfla_2472 ribulose-5-phosphate 3-epimerase; TIGRFAM: ribulose-phosphate 3-epimerase; PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (236 aa)
trpCPFAM: Indole-3-glycerol phosphate synthase; KEGG: mfa:Mfla_2465 indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (262 aa)
Your Current Organism:
Methylotenera mobilis JLW8
NCBI taxonomy Id: 583345
Other names: M. mobilis JLW8, Methylotenera mobilis str. JLW8, Methylotenera mobilis strain JLW8
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