(23 nodes) Mixed, incl. ABC transporter, TroCD-like, and Metal ion homeostasis network (Proteus mirabilis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND11480.1	Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
	feoC	Ferrous iron transporter C; May function as a transcriptional regulator that controls feoABC expression. (77 aa)
	feoB	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (776 aa)
	feoA	Ferrous iron transporter A; Derived by automated computational analysis using gene prediction method: Protein Homology. (78 aa)
	AND11484.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
	zur	Transcriptional repressor; Acts as a negative controlling element, employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (176 aa)
	znuA	Zinc ABC transporter substrate-binding protein; Involved in transport of zinc(II) with ZnuA and C; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. (314 aa)
	znuC	Zinc ABC transporter ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (241 aa)
	znuB	High-affinity zinc transporter membrane component; Involved in transport of zinc(II) with ZnuA and C; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
	AND13269.1	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family. (302 aa)
	sitB	Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
	sitC	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
	sitD	Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
	AND13273.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the fructosamine kinase family. (290 aa)
	yccU	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (137 aa)
	AND13775.1	LexA regulated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
	fldA	Flavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (175 aa)
	fur	Transcriptional repressor; Negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family. (148 aa)
	AND14199.1	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
	AND14200.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (68 aa)
	AND14201.1	Carbon starvation protein A; Derived by automated computational analysis using gene prediction method: Protein Homology. (716 aa)
	zinT	Metal-binding protein ZinT; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
	rpmE2	50S ribosomal protein L31; Derived by automated computational analysis using gene prediction method: Protein Homology. (82 aa)

Your Current Organism:

Proteus mirabilis

NCBI taxonomy Id: 584
Other names: ATCC 29906, CCUG 26767, CIP 103181, DSM 4479, LMG 3257, LMG:3257, NCTC 11938, P. mirabilis

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND11480.1	feoB	AOUC001_00870	AOUC001_00880	Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.	0.415
AND11480.1	feoC	AOUC001_00870	AOUC001_00875	Peroxiredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.	Ferrous iron transporter C; May function as a transcriptional regulator that controls feoABC expression.	0.436
AND13269.1	AND13273.1	AOUC001_10395	AOUC001_10415	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the fructosamine kinase family.	0.475
AND13269.1	AND14199.1	AOUC001_10395	AOUC001_15425	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.771
AND13269.1	fur	AOUC001_10395	AOUC001_13090	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	Transcriptional repressor; Negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.	0.458
AND13269.1	sitB	AOUC001_10395	AOUC001_10400	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
AND13269.1	sitC	AOUC001_10395	AOUC001_10405	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AND13269.1	sitD	AOUC001_10395	AOUC001_10410	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
AND13269.1	zinT	AOUC001_10395	AOUC001_17660	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	Metal-binding protein ZinT; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.946
AND13269.1	znuA	AOUC001_10395	AOUC001_09895	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	Zinc ABC transporter substrate-binding protein; Involved in transport of zinc(II) with ZnuA and C; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	0.460
AND13269.1	znuB	AOUC001_10395	AOUC001_09905	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	High-affinity zinc transporter membrane component; Involved in transport of zinc(II) with ZnuA and C; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.883
AND13269.1	znuC	AOUC001_10395	AOUC001_09900	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	Zinc ABC transporter ATP-binding protein ZnuC; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.	0.836
AND13273.1	AND13269.1	AOUC001_10415	AOUC001_10395	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the fructosamine kinase family.	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	0.475
AND13273.1	sitB	AOUC001_10415	AOUC001_10400	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the fructosamine kinase family.	Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.475
AND13273.1	sitC	AOUC001_10415	AOUC001_10405	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the fructosamine kinase family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.475
AND13273.1	sitD	AOUC001_10415	AOUC001_10410	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the fructosamine kinase family.	Iron ABC transporter permease; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.475
AND13775.1	fldA	AOUC001_13080	AOUC001_13085	LexA regulated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Flavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family.	0.896
AND13775.1	fur	AOUC001_13080	AOUC001_13090	LexA regulated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Transcriptional repressor; Negatively regulates a number of operons that encode enzymes involved in iron transport; activated by manganese; forms a homodimer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.	0.812
AND14199.1	AND13269.1	AOUC001_15425	AOUC001_10395	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Iron-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial solute-binding protein 9 family.	0.771
AND14199.1	AND14200.1	AOUC001_15425	AOUC001_15430	GTP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.949