STRINGSTRING
AND14961.1 AND14961.1 mfd mfd AND11775.1 AND11775.1 fimC_4 fimC_4 AND11779.1 AND11779.1 AND11780.1 AND11780.1 hycH hycH prfC prfC cpdA cpdA parE parE parC parC surA surA lptD lptD rapA rapA recC recC recB recB recD recD mltA mltA AND11936.1 AND11936.1 frr frr uppS uppS bamA bamA AND11961.1 AND11961.1 papC_7 papC_7 focC_6 focC_6 papD_3 papD_3 AND12023.1 AND12023.1 ftsI ftsI murE murE murF murF mraY mraY murD murD ftsW ftsW murG murG murC murC ftsQ ftsQ ftsZ ftsZ zapD zapD ppdD ppdD zapA zapA AND15094.1 AND15094.1 AND12253.1 AND12253.1 smpA smpA srmB srmB pmfD pmfD AND12390.1 AND12390.1 mltF mltF iscS iscS iscU iscU iscA iscA hscB hscB hscA hscA iscX iscX AND12420.1 AND12420.1 yfgL yfgL zipA zipA mlaA mlaA mrgA mrgA AND12493.1 AND12493.1 AND12495.1 AND12495.1 gyrA gyrA AND12563.1 AND12563.1 AND15101.1 AND15101.1 flhD flhD flhC flhC flhB flhB flhA flhA flgN flgN flgM flgM flgA flgA AND12686.1 AND12686.1 flgK flgK fliR fliR fliQ fliQ fliP fliP fliO fliO AND12702.1 AND12702.1 fliJ fliJ fliH fliH fliT fliT fliS fliS bamC bamC topB topB AND12842.1 AND12842.1 focC_5 focC_5 AND12865.1 AND12865.1 sufA sufA AND12911.1 AND12911.1 sufC sufC sufD sufD sufE sufE lpp lpp grxD grxD topA topA ddlA ddlA AND13098.1 AND13098.1 AND13139.1 AND13139.1 AND13140.1 AND13140.1 AND13146.1 AND13146.1 AND13147.1 AND13147.1 minC minC minD minD AND13168.1 AND13168.1 ruvB ruvB ruvA ruvA cutC-2 cutC-2 murJ murJ prfA prfA AND13236.1 AND13236.1 pefC pefC rplT rplT AND13268.1 AND13268.1 AND13286.1 AND13286.1 AND13287.1 AND13287.1 AND13294.1 AND13294.1 AND13329.1 AND13329.1 AND11763.1 AND11763.1 AND11760.1 AND11760.1 AND11731.1 AND11731.1 AND11729.1 AND11729.1 atfB atfB AND11667.1 AND11667.1 dnaB dnaB hupA hupA engB engB recG recG AND11522.1 AND11522.1 gntY gntY AND11408.1 AND11408.1 AND11406.1 AND11406.1 AND11405.1 AND11405.1 nagZ nagZ mltG mltG lpxT lpxT spr spr AND13494.1 AND13494.1 helD helD sulA sulA pqiB pqiB zapC zapC mukB mukB mukE mukE mukF mukF AND13604.1 AND13604.1 AND13647.1 AND13647.1 ybjG ybjG dacC dacC apbC apbC dps dps dinG dinG rhlE rhlE cpoB cpoB AND13764.1 AND13764.1 fimC_3 fimC_3 htrE_1 htrE_1 AND15134.1 AND15134.1 AND13821.1 AND13821.1 AND13833.1 AND13833.1 AND13868.1 AND13868.1 lptE lptE rsfS rsfS mrdA mrdA mrdB mrdB AND15138.1 AND15138.1 dacA dacA bamD bamD ypjD ypjD AND13963.1 AND13963.1 AND13972.1 AND13972.1 mltC mltC AND14035.1 AND14035.1 topB_2 topB_2 dnaB-2 dnaB-2 mrpD_1 mrpD_1 AND14093.1 AND14093.1 mrpD_2 mrpD_2 AND14102.1 AND14102.1 mltD mltD erpA erpA mrcB mrcB AND14206.1 AND14206.1 hupB hupB dbpA dbpA AND14335.1 AND14335.1 ureE ureE mtgA mtgA AND14383.1 AND14383.1 murA murA yrbA yrbA mlaB mlaB mlaC mlaC mlaF mlaF lptC lptC lptA lptA frdC frdC narJ narJ AND14524.1 AND14524.1 fimD_5 fimD_5 AND14559.1 AND14559.1 AND14564.1 AND14564.1 deaD deaD AND15160.1 AND15160.1 argR argR mpl mpl AND14642.1 AND14642.1 AND14643.1 AND14643.1 recQ recQ uvrD uvrD cyaY cyaY rep rep yafQ yafQ yifE yifE AND14698.1 AND14698.1 murB murB murI murI priA priA ftsN ftsN zapB zapB AND14776.1 AND14776.1 secB secB gyrB gyrB AND14891.1 AND14891.1 AND14892.1 AND14892.1 AND14893.1 AND14893.1 glmU glmU
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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co-expression
protein homology
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AND14961.1Fimbrial assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1151 aa)
AND11775.1Fimbrial chaperone protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
fimC_4Fimbrial chaperone protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
AND11779.1Fimbrial chaperone protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
AND11780.1Usher protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (847 aa)
hycHFormate hydrogenlyase maturation protein HycH; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
prfCPeptide chain release factor 3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa)
cpdA3',5'-cyclic-AMP phosphodiesterase; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. (279 aa)
parEDNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (631 aa)
parCDNA topoisomerase IV; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (985 aa)
surAPeptidylprolyl isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (436 aa)
lptDLPS-assembly protein LptD; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (788 aa)
rapARNA polymerase-binding ATPase; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (967 aa)
recCExonuclease V subunit gamma; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Hol [...] (1125 aa)
recBExodeoxyribonuclease V subunit beta; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and rep [...] (1212 aa)
recDExonuclease V subunit alpha; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Hol [...] (638 aa)
mltAMurein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (364 aa)
AND11936.1Cysteine desulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
frrRibosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa)
uppSUDP pyrophosphate synthase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (252 aa)
bamAOuter membrane protein assembly factor BamA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. (797 aa)
AND11961.1Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the skp family. (165 aa)
papC_7Fimbrial assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (832 aa)
focC_6Long polar fimbrial chaperone LpfB; Binds with fimbrial subunit LpfA; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
papD_3Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
AND12023.1Fimbrial assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (835 aa)
ftsICell division protein FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. (598 aa)
murEUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (495 aa)
murFUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (460 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
murDUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (436 aa)
ftsWCell division protein FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (397 aa)
murGUDP-diphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (360 aa)
murCUDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (487 aa)
ftsQCell division protein FtsQ; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (262 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (388 aa)
zapDCell division protein ZapD; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (250 aa)
ppdDPilus assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (147 aa)
zapAZ-ring-associated protein; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (109 aa)
AND15094.1Catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
AND12253.1Sugar transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (871 aa)
smpAMembrane biogenesis protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (120 aa)
srmBATP-dependent RNA helicase SrmB; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit at low temperature. Exhibits RNA-stimulated ATP hydrolysis and RNA unwinding activity; Belongs to the DEAD box helicase family. SrmB subfamily. (451 aa)
pmfDMolecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
AND12390.1Fimbrial assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (828 aa)
mltFLytic transglycosylase F; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (489 aa)
iscSCysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. (404 aa)
iscUFe-S cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. (128 aa)
iscAIron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system TrxA/TrxB. (107 aa)
hscBCo-chaperone HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. (173 aa)
hscAFe-S protein assembly chaperone HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. Involved in the maturation of IscU. (616 aa)
iscXFe-S assembly protein IscX; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)
AND12420.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
yfgLOuter membrane protein assembly factor BamB; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (390 aa)
zipACell division protein ZipA; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (351 aa)
mlaAABC transporter permease; Involved in maintaining OM lipid asymmetry; Derived by automated computational analysis using gene prediction method: Protein Homology. (247 aa)
mrgADNA starvation/stationary phase protection protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family. (184 aa)
AND12493.1Type I-E CRISPR-associated protein Cas5/CasD; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
AND12495.1Subtype I-E CRISPR-associated endonuclease Cas1; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (877 aa)
AND12563.1DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
AND15101.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (62 aa)
flhDFlagellar transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (116 aa)
flhCTranscriptional regulator FlhC; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (193 aa)
flhBFlagellar biosynthetic protein FlhB; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (382 aa)
flhAFlagellar biosynthesis protein FlhA; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin (By similarity); Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (696 aa)
flgNFlagellar biosynthesis protein FlgN; Required for the efficient initiation of filament assembly; Belongs to the FlgN family. (146 aa)
flgMFlagellar biosynthesis anti-sigma factor FlgM; Responsible for the coupling of flagellin expression to flagellar assembly by preventing expression of the flagellin genes when a component of the middle class of proteins is defective. It negatively regulates flagellar genes by inhibiting the activity of FliA by directly binding to FliA (By similarity). (99 aa)
flgAFlagellar biosynthesis protein FlgA; Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P- ring assembly; Belongs to the FlgA family. (218 aa)
AND12686.1Flagellar biosynthesis protein FlgD; Required for flagellar hook formation. May act as a scaffolding protein. (268 aa)
flgKWith FlgL acts as a hook filament junction protein to join the flagellar filament to the hook; Derived by automated computational analysis using gene prediction method: Protein Homology. (547 aa)
fliRFlagellar biosynthetic protein FliR; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (260 aa)
fliQFlagellar export apparatus protein FliQ; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
fliPFlagellar biosynthetic protein FliP; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (256 aa)
fliOFlagellar protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (148 aa)
AND12702.1Flagellar hook-length control protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
fliJFlagellar protein FliJ; Flagellar protein that affects chemotactic events. Belongs to the FliJ family. (148 aa)
fliHFlagellar assembly protein FliH; Derived by automated computational analysis using gene prediction method: Protein Homology. (240 aa)
fliTFlagellar assembly protein FliT; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
fliSFlagellar protein FliS; Flagellin specific chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
bamCPorin; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (348 aa)
topBDNA topoisomerase III; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA su [...] (655 aa)
AND12842.1Capsular biosynthesis protein CpsI; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
focC_5Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
AND12865.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (867 aa)
sufAFe-S cluster assembly scaffold SufA; Functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]; [4Fe-4S]) are assembled; forms a homodimer; similar to IscA protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HesB/IscA family. (122 aa)
AND12911.1Fe-S cluster assembly protein SufB; With SufCD activates cysteine desulfurase SufS; Derived by automated computational analysis using gene prediction method: Protein Homology. (498 aa)
sufCABC transporter ATP-binding protein; Part of SUF system involved in inserting iron-sulfur clusters into proteins; in Escherichia coli this protein forms a complex with SufBD; the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
sufDFeS cluster assembly protein SufD; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
sufECysteine desufuration protein SufE; Acts with SufS to catalyze the formation of L-alanine from L-cysteine; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
lppMurein lipoprotein; A highly abundant outer membrane lipoprotein that controls the distance between the inner and outer membranes. The only protein known to be covalently linked to the peptidoglycan network (PGN). Also non-covalently binds the PGN. The link between the cell outer membrane and PGN contributes to maintenance of the structural and functional integrity of the cell envelope, and maintains the correct distance between the PGN and the outer membrane. (79 aa)
grxDGlutaredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutaredoxin family. Monothiol subfamily. (112 aa)
topADNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...] (865 aa)
ddlAD-alanine--D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (366 aa)
AND13098.1Dimethyl sulfoxide reductase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (814 aa)
AND13139.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
AND13140.1Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (797 aa)
AND13146.1Fimbrial chaperone protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
AND13147.1Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (804 aa)
minCSeptum formation inhibitor; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (233 aa)
minDSeptum site-determining protein MinD; ATPase; with MinC inhibits cell division by blocking formation of the polar Z ring septums; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
AND13168.1ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (643 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (207 aa)
cutC-2Copper homeostasis protein CutC; Participates in the control of copper homeostasis. Belongs to the CutC family. (250 aa)
murJLipid II flippase MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (511 aa)
prfAPeptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (360 aa)
AND13236.1Fimbrial chaperone protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
pefCFimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (791 aa)
rplT50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa)
AND13268.1Murein transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (233 aa)
AND13286.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (772 aa)
AND13287.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (80 aa)
AND13294.1Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
AND13329.1Phage tail protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (979 aa)
AND11763.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (198 aa)
AND11760.1DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1644 aa)
AND11731.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
AND11729.1Protein bax; Derived by automated computational analysis using gene prediction method: Protein Homology. (264 aa)
atfBType 1 fimbrial chaperone protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
AND11667.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (843 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (469 aa)
hupADNA-binding protein; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (90 aa)
engBYihA family ribosome biogenesis GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (207 aa)
recGATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily. (695 aa)
AND11522.1GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: Protein Homology. (611 aa)
gntYFe-S biogenesis protein NfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (192 aa)
AND11408.1Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
AND11406.1Outer membrane usher protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (831 aa)
AND11405.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
nagZbeta-N-acetylhexosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (339 aa)
mltGAminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. (340 aa)
lpxTHypothetical protein; Involved in the modification of the lipid A domain of lipopolysaccharides (LPS). Transfers a phosphate group from undecaprenyl pyrophosphate (C55-PP) to lipid A to form lipid A 1- diphosphate. Contributes to the recycling of undecaprenyl phosphate (C55-P); Belongs to the LpxT phosphotransferase family. (240 aa)
sprLipoprotein Spr; Mutational suppressor of prc thermosensitivity; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
AND13494.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
helDDNA helicase IV; Catalyzes the ATP-dependent unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand; Derived by automated computational analysis using gene prediction method: Protein Homology. (683 aa)
sulAPhosphatidate cytidylyltransferase; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (184 aa)
pqiBParaquat-inducible protein B; Derived by automated computational analysis using gene prediction method: Protein Homology. (550 aa)
zapCCell division protein ZapC; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (183 aa)
mukBCell division protein MukB; SMC (structural maintenance of chromosomes) family of proteins; involved in chromosome condensatin and partitioning; forms a homodimer and the C-terminal is essential for DNA-binding activity while the purified N-terminal domain binds FtsZ; mutations result in cell division defects; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SMC family. MukB subfamily. (1485 aa)
mukEChromosome partitioning protein MukE; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. (243 aa)
mukFChromosome partition protein MukF; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. (440 aa)
AND13604.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
AND13647.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa)
ybjGUndecaprenyl-diphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
dacCD-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (400 aa)
apbCFe-S-binding ATPase; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (370 aa)
dpsBinds DNA in a non-sequence-specific manner and is abundant during stationary phase; forms a DNA-protein crystal that protects DNA from damage; required for normal starvation response and long-term stationary viability; forms a homododecameric complex and sequesters iron which provides protection against oxidative damage; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Dps family. (168 aa)
dinGATP-dependent DNA helicase DinG; DNA-dependent ATPase and 5'-3' DNA helicase. (702 aa)
rhlEATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (464 aa)
cpoBCell division protein CpoB; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (257 aa)
AND13764.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (691 aa)
fimC_3Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
htrE_1F17 fimbrial usher; Derived by automated computational analysis using gene prediction method: Protein Homology. (844 aa)
AND15134.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (62 aa)
AND13821.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
AND13833.1Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
AND13868.1Protein-disulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (678 aa)
lptELPS biosynthesis protein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (182 aa)
rsfSRibosome silencing factor RsfS; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (105 aa)
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (631 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa)
AND15138.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
dacAD-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (403 aa)
bamDMembrane biogenesis protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. (244 aa)
ypjDHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
AND13963.1Type IV pili twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
AND13972.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (108 aa)
mltCMurein transglycosylase C; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (356 aa)
AND14035.1Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
topB_2DNA topoisomerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (684 aa)
dnaB-2Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (450 aa)
mrpD_1Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
AND14093.1Fimbrial assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (871 aa)
mrpD_2Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
AND14102.1Fimbrial assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (875 aa)
mltDLytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
erpAIron-sulfur cluster insertion protein ErpA; Required for insertion of 4Fe-4S clusters for at least IspG. (114 aa)
mrcBPenicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (770 aa)
AND14206.1Prepilin peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
hupBDNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (96 aa)
dbpAATP-dependent RNA helicase DbpA; DEAD-box RNA helicase involved in the assembly of the 50S ribosomal subunit. Has an RNA-dependent ATPase activity, which is specific for 23S rRNA, and a 3' to 5' RNA helicase activity that uses the energy of ATP hydrolysis to destabilize and unwind short rRNA duplexes. (457 aa)
AND14335.1Murein transglycosylase; Catalyzes the cleavage of the glycosidic bonds between N-acetylmuramic acid and N-acetylglucosamine residues in peptidoglycan; Derived by automated computational analysis using gene prediction method: Protein Homology. (639 aa)
ureEUrease accessory protein UreE; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. (161 aa)
mtgAMonofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. (233 aa)
AND14383.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (420 aa)
yrbACell division protein BolA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (84 aa)
mlaBAnti-sigma B factor antagonist; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
mlaCABC transporter substrate-binding protein; Involved in maintaining outer membrane lipid asymmetry; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
mlaFABC transporter maintaining outer membrane lipid asymmetry; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
lptCLPS export ABC transporter periplasmic protein LptC; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (192 aa)
lptALipopolysaccharide transport periplasmic protein LptA; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm. (177 aa)
frdCFumarate reductase subunit C; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
narJDelta subunit of nitrate reductase 1; chaperone for the insertion of the molybdenum cofactor and assembly of nitrate reductase 1; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
AND14524.1Peptide chain release factor H; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
fimD_5Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (873 aa)
AND14559.1Molecular chaperone FimC; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
AND14564.1Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)
deaDDEAD/DEAH family ATP-dependent RNA helicase; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation. (611 aa)
AND15160.1RNA binding protein found associated to pre-50S subunit of the ribosome; putative role in ribosome assembly; necessary for optimal growth but not cell viability; Derived by automated computational analysis using gene prediction method: Protein Homology. (97 aa)
argRArginine repressor; Regulates arginine biosynthesis genes. (156 aa)
mplUDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. (459 aa)
AND14642.1Fimbrial chaperone protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
AND14643.1Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (841 aa)
recQATP-dependent DNA helicase RecQ; Functions in blocking illegitimate recombination, enhancing topoisomerase activity, initiating SOS signaling and clearing blocked replication forks; component of the RecF recombinational pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (609 aa)
uvrDDNA helicase II; Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present; involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair; Derived by automated computational analysis using gene prediction method: Protein Homology. (718 aa)
cyaYIron donor protein CyaY; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (105 aa)
repATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction. (673 aa)
yafQmRNA interferase YafQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
yifEHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (112 aa)
AND14698.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (344 aa)
murIGlutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. (288 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (733 aa)
ftsNCell division protein FtsN; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. (264 aa)
zapBSeptal ring assembly protein ZapB; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (80 aa)
AND14776.1ferredoxin--NADP(+) reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
secBProtein-export chaperone SecB; One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA. (157 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (804 aa)
AND14891.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
AND14892.1Fimbrial assembly protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (637 aa)
AND14893.1Fimbrial protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (457 aa)
Your Current Organism:
Proteus mirabilis
NCBI taxonomy Id: 584
Other names: ATCC 29906, CCUG 26767, CIP 103181, DSM 4479, LMG 3257, LMG:3257, NCTC 11938, P. mirabilis
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