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nuoL nuoL AND11438.1 AND11438.1 AND11440.1 AND11440.1 AND11658.1 AND11658.1 fixA_3 fixA_3 fixB_2 fixB_2 AND11755.1 AND11755.1 AND11756.1 AND11756.1 AND11786.1 AND11786.1 hyfB hyfB hycD hycD AND11789.1 AND11789.1 hyfE hyfE hyfF hyfF hycE hycE nuoB nuoB AND11865.1 AND11865.1 AND11947.1 AND11947.1 yceJ yceJ fldB fldB fdx fdx phsC phsC AND12453.1 AND12453.1 nuoA nuoA nuoB-2 nuoB-2 nuoC nuoC nuoE nuoE nuoF nuoF nuoG nuoG nuoJ nuoJ nuoK nuoK fdoI fdoI AND14870.1 AND14870.1 AND14869.1 AND14869.1 AND14545.1 AND14545.1 AND14481.1 AND14481.1 AND14464.1 AND14464.1 hydN hydN frdB frdB AND14453.1 AND14453.1 hybO hybO hybA hybA hybC hybC hybE hybE AND14269.1 AND14269.1 AND14266.1 AND14266.1 cyoD cyoD cyoC cyoC AND14235.1 AND14235.1 AND14234.1 AND14234.1 AND14171.1 AND14171.1 nqrB nqrB nqrE nqrE nqrF nqrF fldA fldA sdhC sdhC sdhA sdhA sdhB sdhB cydA cydA ybgT ybgT AND13681.1 AND13681.1 grxA grxA dld dld azoR azoR AND13131.1 AND13131.1 AND13129.1 AND13129.1 dmsC_2 dmsC_2 rsxA rsxA rsxB rsxB rnfC rnfC rsxD rsxD rsxG rsxG rnfE rnfE AND12893.1 AND12893.1 dsbB dsbB AND12634.1 AND12634.1 dmsC_1 dmsC_1 petF1 petF1 nuoN nuoN nuoM nuoM
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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nuoLNADH-quinone oxidoreductase subunit L; Catalyzes the transfer of electrons from NADH to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (611 aa)
AND11438.1Reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
AND11440.1Dimethyl sulfoxide reductase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology. (805 aa)
AND11658.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
fixA_3Electron transfer flavoprotein; Required for anaerobic carnitine reduction. May bring reductant to CaiA. (257 aa)
fixB_2Electron transfer flavoprotein subunit alpha; Required for anaerobic carnitine reduction. May bring reductant to CaiA. (312 aa)
AND11755.1Electron transfer flavoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
AND11756.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (313 aa)
AND11786.1Electron transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa)
hyfBHydrogenase 4 subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (671 aa)
hycDHydrogenase 3 membrane subunit; Formate hydrogenlyase subunit 4; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AND11789.1Hydrogenase 4 subunit D; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
hyfEHydrogenase 4 membrane subunit; Interacts with formate dehydrogenase to produce an active formate hydrogenlyase complex which cleaves formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (216 aa)
hyfFHydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
hycEHydrogenase 3 large subunit; Formate hydrogenlyase subunit 5; HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa)
nuoBHydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
AND11865.1Cytochrome D ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
AND11947.1Flavodoxin; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
yceJDerived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
fldBFlavodoxin FldB; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (172 aa)
fdx2Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
phsCThiosulfate reductase cytochrome B subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
AND12453.1Thiosulfate reductase PhsA; Catalyzes the production of hydrogen sulfide from thiosulfate; Derived by automated computational analysis using gene prediction method: Protein Homology. (759 aa)
nuoANADH-quinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (150 aa)
nuoB-2NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa)
nuoCNADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (598 aa)
nuoENADH-quinone oxidoreductase subunit E; Catalyzes the transfer of electrons from NADH to quinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (181 aa)
nuoFNADH-quinone oxidoreductase subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (454 aa)
nuoGNADH-quinone oxidoreductase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (910 aa)
nuoJNADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (177 aa)
nuoKNADH-quinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
fdoIFormate dehydrogenase; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
AND14870.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (803 aa)
AND14869.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AND14545.1Anaerobic ribonucleotide reductase-activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (154 aa)
AND14481.1Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
AND14464.1Spermidine/putrescine ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
hydNEffector protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
frdBPart of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
AND14453.1Fumarate reductase (quinol) flavoprotein subunit; Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (598 aa)
hybOHydrogenase 2 small subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology. (374 aa)
hybAHydrogenase 2 protein HybA; Fe-S ferrodoxin type component; participates in the periplasmic electron-transferring activity of hydrogenase 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
hybCHydrogenase 2 large subunit; Involved in hydrogen uptake; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
hybEHydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
AND14269.1Thiosulfate reductase cytochrome B subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AND14266.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (700 aa)
cyoDCytochrome o ubiquinol oxidase subunit IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
cyoCCytochrome o ubiquinol oxidase subunit III; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
AND14235.1Cytochrome o ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family. (660 aa)
AND14234.1Cytochrome ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
AND14171.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa)
nqrBNADH:ubiquinone reductase (Na(+)-transporting) subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (412 aa)
nqrENADH:ubiquinone reductase (Na(+)-transporting) subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (198 aa)
nqrFNADH:ubiquinone reductase (Na(+)-transporting) subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (408 aa)
fldAFlavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (175 aa)
sdhCSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (125 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
cydACytochrome d terminal oxidase subunit 1; Part of the aerobic respiratory chain; catalyzes the ubiquinol to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
ybgTCyd operon protein YbgT; Derived by automated computational analysis using gene prediction method: Protein Homology. (37 aa)
AND13681.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
grxAGlutaredoxin; Functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
dldD-lactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (589 aa)
azoRFMN-dependent NADH-azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (206 aa)
AND13131.1Dimethyl sulfoxide reductase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (798 aa)
AND13129.1Dimethyl sulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
dmsC_2Dimethylsulfoxide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
rsxAElectron transport complex subunit RsxA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (193 aa)
rsxBElectron transport complex subunit RsxB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (208 aa)
rnfCElectron transport complex subunit RsxC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (835 aa)
rsxDElectron transport complex subunit RsxD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (358 aa)
rsxGElectron transport complex subunit RsxG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (208 aa)
rnfEElectron transport complex subunit RsxE; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (234 aa)
AND12893.1Cytochrome D ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
dsbBDisulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (174 aa)
AND12634.1Dimethyl sulfoxide reductase subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (810 aa)
dmsC_1Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
petF1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)
nuoNNADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (489 aa)
nuoMNADH-quinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (509 aa)
Your Current Organism:
Proteus mirabilis
NCBI taxonomy Id: 584
Other names: ATCC 29906, CCUG 26767, CIP 103181, DSM 4479, LMG 3257, LMG:3257, NCTC 11938, P. mirabilis
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