STRINGSTRING
sucD sucD EDC28_103252 EDC28_103252 ackA ackA EDC28_109173 EDC28_109173 EDC28_101110 EDC28_101110 GCA_001247655_02477 GCA_001247655_02477 acsA acsA EDC28_104198 EDC28_104198 EDC28_104200 EDC28_104200 prpB prpB EDC28_10599 EDC28_10599 accD accD fadI fadI EDC28_101436 EDC28_101436 EDC28_101428 EDC28_101428 EDC28_106274 EDC28_106274 EDC28_106273 EDC28_106273 EDC28_106270 EDC28_106270 EDC28_106262 EDC28_106262 EDC28_103397 EDC28_103397 EDC28_103396 EDC28_103396 EDC28_103393 EDC28_103393 EDC28_103373 EDC28_103373 accA accA EDC28_10745 EDC28_10745 EDC28_10744 EDC28_10744 EDC28_107246 EDC28_107246 sucC sucC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
EDC28_103252Unannotated protein. (324 aa)
ackAUnannotated protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (372 aa)
EDC28_109173Unannotated protein. (468 aa)
EDC28_101110Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
GCA_001247655_02477Unannotated protein. (411 aa)
acsAUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (645 aa)
EDC28_104198Unannotated protein. (391 aa)
EDC28_104200Unannotated protein; Belongs to the citrate synthase family. (375 aa)
prpBUnannotated protein; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (290 aa)
EDC28_10599Unannotated protein. (299 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (289 aa)
fadIUnannotated protein; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (437 aa)
EDC28_101436Unannotated protein. (474 aa)
EDC28_101428Unannotated protein; Belongs to the aconitase/IPM isomerase family. (865 aa)
EDC28_106274Unannotated protein; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
EDC28_106273Unannotated protein. (496 aa)
EDC28_106270Unannotated protein. (369 aa)
EDC28_106262Unannotated protein; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (679 aa)
EDC28_103397Unannotated protein. (260 aa)
EDC28_103396Unannotated protein. (275 aa)
EDC28_103393Unannotated protein. (551 aa)
EDC28_103373Unannotated protein. (327 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa)
EDC28_10745Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (152 aa)
EDC28_10744Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
EDC28_107246Unannotated protein. (498 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
Your Current Organism:
Gallaecimonas pentaromativorans
NCBI taxonomy Id: 584787
Other names: CECT 7479, DSM 21945, G. pentaromativorans, Gallaecimonas pentaromativorans Rodriguez-Blanco et al. 2010, gamma proteobacterium CEE_131, strain CEE_131
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