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narI narI dmsB-3 dmsB-3 dmsB-4 dmsB-4 dmsA-2 dmsA-2 narG narG nrdB nrdB nrdA nrdA hyfG hyfG hycG hycG dmsB dmsB DR95_2566 DR95_2566 dmsB-2 dmsB-2 glpD glpD ttrA ttrA aceE aceE gltD gltD gltB gltB hybO hybO efeU efeU nrdF2 nrdF2 nuoE nuoE nuoF nuoF glpA glpA fdhF_1 fdhF_1 fdhF_2 fdhF_2 narH narH aceF aceF gcvH gcvH gcvP gcvP gpsA gpsA fdoI fdoI guaB guaB nrdE2 nrdE2 nuoC nuoC sdhC sdhC sucA sucA sucB sucB ndh ndh
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
narInarI: respiratory nitrate reductase, gamma subunit. (225 aa)
dmsB-3DMSO_dmsB: dimethylsulfoxide reductase, chain B. (209 aa)
dmsB-4DMSO_dmsB: dimethylsulfoxide reductase, chain B. (205 aa)
dmsA-2Anaerobic dimethyl sulfoxide reductase chain A; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (812 aa)
narGnarG: nitrate reductase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1253 aa)
nrdBRibonucleoside-diphosphate reductase 1 subunit beta. (376 aa)
nrdARibonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (763 aa)
hyfGHydrogenase-4 component G. (577 aa)
hycGNADH ubiquinone oxidoreductase, 20 Kd subunit. (260 aa)
dmsBDMSO_dmsB: dimethylsulfoxide reductase, chain B. (205 aa)
DR95_2566Fdh-alpha: formate dehydrogenase, alpha subunit. (722 aa)
dmsB-2DMSO_dmsB: dimethylsulfoxide reductase, chain B. (213 aa)
glpDAerobic glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (497 aa)
ttrAMolybdopterin oxidoreductase Fe4S4 domain protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1026 aa)
aceEPyruvate dehydrogenase (acetyl-transferring), homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa)
gltDGlutamate synthase [NADPH] small chain. (465 aa)
gltBGlutamine amidotransferases class-II family protein. (1486 aa)
hybOHydrogenase-2 small chain. (374 aa)
efeUIron permease FTR1 family protein. (278 aa)
nrdF2Ribonucleoside-diphosphate reductase subunit beta nrdF2; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (322 aa)
nuoENADH-quinone oxidoreductase subunit E. (181 aa)
nuoFNADH oxidoreductase (quinone), F subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (454 aa)
glpAglycerol3P_GlpA: glycerol-3-phosphate dehydrogenase, anaerobic, A subunit; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (551 aa)
fdhF_1Fdh-alpha: formate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (558 aa)
fdhF_2Molybdopterin oxidoreductase Fe4S4 domain protein. (139 aa)
narHnarH: nitrate reductase, beta subunit. (517 aa)
aceFDihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (619 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (958 aa)
gpsAKetopantoate reductase PanE/ApbA family protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa)
fdoIformate-DH-gamm: formate dehydrogenase, gamma subunit. (218 aa)
guaBInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (488 aa)
nrdE2Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (693 aa)
nuoCNADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (598 aa)
sdhCsucc_dehyd_cytB: succinate dehydrogenase, cytochrome b556 subunit. (125 aa)
sucA2oxo_dh_E1: oxoglutarate dehydrogenase (succinyl-transferring), E1 component. (934 aa)
sucBDihydrolipoyllysine-residue succinyltransferase, E2 component of oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (401 aa)
ndhNADH dehydrogenase. (435 aa)
Your Current Organism:
Proteus vulgaris
NCBI taxonomy Id: 585
Other names: ATCC 29905, CCUG 35382, CCUG 39507, CDC PR1, CIP 104989, DSM 13387, LMG 16708, LMG:16708, NCTC 13145, P. vulgaris, strain PR 1
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