5 items (Escherichia coli IAI1) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ybiW	Putative glycyl radical cofactor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (810 aa)
	ybiY	Putative AdoMet-dependent glycyl radical activating enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (308 aa)
	fsaA	Fructose-6-phosphate aldolase 1; Function experimentally demonstrated in the studied species; enzyme. (220 aa)
	pflA	Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (246 aa)
	yfiD	Pyruvate formate lyase subunit; Acts as a radical domain for damaged PFL and possibly other radical proteins. (127 aa)

Your Current Organism:

Escherichia coli IAI1

NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
fsaA	ybiW	ECIAI1_0864	ECIAI1_0862	Fructose-6-phosphate aldolase 1; Function experimentally demonstrated in the studied species; enzyme.	Putative glycyl radical cofactor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.703
fsaA	ybiY	ECIAI1_0864	ECIAI1_0863	Fructose-6-phosphate aldolase 1; Function experimentally demonstrated in the studied species; enzyme.	Putative AdoMet-dependent glycyl radical activating enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.578
pflA	ybiW	ECIAI1_0942	ECIAI1_0862	Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	Putative glycyl radical cofactor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.796
pflA	yfiD	ECIAI1_0942	ECIAI1_2696	Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	Pyruvate formate lyase subunit; Acts as a radical domain for damaged PFL and possibly other radical proteins.	0.805
ybiW	fsaA	ECIAI1_0862	ECIAI1_0864	Putative glycyl radical cofactor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Fructose-6-phosphate aldolase 1; Function experimentally demonstrated in the studied species; enzyme.	0.703
ybiW	pflA	ECIAI1_0862	ECIAI1_0942	Putative glycyl radical cofactor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.796
ybiW	ybiY	ECIAI1_0862	ECIAI1_0863	Putative glycyl radical cofactor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative AdoMet-dependent glycyl radical activating enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.971
ybiY	fsaA	ECIAI1_0863	ECIAI1_0864	Putative AdoMet-dependent glycyl radical activating enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Fructose-6-phosphate aldolase 1; Function experimentally demonstrated in the studied species; enzyme.	0.578
ybiY	ybiW	ECIAI1_0863	ECIAI1_0862	Putative AdoMet-dependent glycyl radical activating enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative glycyl radical cofactor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.971
ybiY	yfiD	ECIAI1_0863	ECIAI1_2696	Putative AdoMet-dependent glycyl radical activating enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Pyruvate formate lyase subunit; Acts as a radical domain for damaged PFL and possibly other radical proteins.	0.765
yfiD	pflA	ECIAI1_2696	ECIAI1_0942	Pyruvate formate lyase subunit; Acts as a radical domain for damaged PFL and possibly other radical proteins.	Pyruvate formate lyase activating enzyme 1; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.	0.805
yfiD	ybiY	ECIAI1_2696	ECIAI1_0863	Pyruvate formate lyase subunit; Acts as a radical domain for damaged PFL and possibly other radical proteins.	Putative AdoMet-dependent glycyl radical activating enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.765