(6 nodes) Mixed, incl. Protein trimerization, and Protein domain specific binding network (Escherichia coli IAI1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ybgC	acyl-CoA thioesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (134 aa)
	tolQ	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component. (230 aa)
	tolR	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component. (142 aa)
	tolB	Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (430 aa)
	pal	Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (173 aa)
	ybgF	Putative RNA binding protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (263 aa)

Your Current Organism:

Escherichia coli IAI1

NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
pal	tolB	ECIAI1_0716	ECIAI1_0715	Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.	0.999
pal	tolQ	ECIAI1_0716	ECIAI1_0712	Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	0.976
pal	tolR	ECIAI1_0716	ECIAI1_0713	Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	0.974
pal	ybgC	ECIAI1_0716	ECIAI1_0711	Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	acyl-CoA thioesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.766
pal	ybgF	ECIAI1_0716	ECIAI1_0717	Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	Putative RNA binding protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.	0.987
tolB	pal	ECIAI1_0715	ECIAI1_0716	Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.	Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	0.999
tolB	tolQ	ECIAI1_0715	ECIAI1_0712	Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	0.997
tolB	tolR	ECIAI1_0715	ECIAI1_0713	Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	0.998
tolB	ybgC	ECIAI1_0715	ECIAI1_0711	Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.	acyl-CoA thioesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.797
tolB	ybgF	ECIAI1_0715	ECIAI1_0717	Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.	Putative RNA binding protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.	0.994
tolQ	pal	ECIAI1_0712	ECIAI1_0716	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	0.976
tolQ	tolB	ECIAI1_0712	ECIAI1_0715	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.	0.997
tolQ	tolR	ECIAI1_0712	ECIAI1_0713	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	0.999
tolQ	ybgC	ECIAI1_0712	ECIAI1_0711	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	acyl-CoA thioesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.978
tolQ	ybgF	ECIAI1_0712	ECIAI1_0717	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	Putative RNA binding protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.	0.934
tolR	pal	ECIAI1_0713	ECIAI1_0716	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.	0.974
tolR	tolB	ECIAI1_0713	ECIAI1_0715	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.	0.998
tolR	tolQ	ECIAI1_0713	ECIAI1_0712	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	0.999
tolR	ybgC	ECIAI1_0713	ECIAI1_0711	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	acyl-CoA thioesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.970
tolR	ybgF	ECIAI1_0713	ECIAI1_0717	Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component.	Putative RNA binding protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.	0.937