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| | yeeD | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the sulfur carrier protein TusA family. (75 aa) |
| | yjtD | rRNA methyltransferase; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA. (228 aa) |
| | yjjK | Fused putative transporter subunits of ABC superfamily: ATP-binding components; Function of strongly homologous gene; putative transporter. (555 aa) |
| | lplA | Fragment of conserved hypothetical protein, putative transcriptionnal regulator (partial); Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Belongs to the LplA family. (338 aa) |
| | prfC | Peptide chain release factor RF-3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | rimI | Acetylase for 30S ribosomal subunit protein S18; Acetylates the N-terminal alanine of ribosomal protein S18. (148 aa) |
| | rsmC | 16S RNA m2G1207 methylase; Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle; Belongs to the methyltransferase superfamily. RsmC family. (343 aa) |
| | kptA | 2'-phosphotransferase; Function experimentally demonstrated in the studied species; enzyme. (184 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (951 aa) |
| | rplI | 50S ribosomal subunit protein L9; Binds to the 23S rRNA. (149 aa) |
| | rpsR | 30S ribosomal subunit protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (75 aa) |
| | rpsF | 30S ribosomal subunit protein S6; Function experimentally demonstrated in the studied species; structure. (131 aa) |
| | rlmB | 23S rRNA (Gm2251)-methyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (243 aa) |
| | hflX | Putative GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (426 aa) |
| | miaA | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (316 aa) |
| | yjeE | ATPase with strong ADP affinity; Function experimentally demonstrated in the studied species; enzyme. (153 aa) |
| | yjeS | Putative Fe-S electron transport protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (379 aa) |
| | poxA | lysyl-tRNA synthetase; With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF- P) on 'Lys-34'. Catalyzes the ATP-dependent activation of (R)-beta- lysine produced by EpmB, forming a lysyl-adenylate, from which the beta-lysyl moiety is then transferred to the epsilon-amino group of EF- P 'Lys-34'; Belongs to the class-II aminoacyl-tRNA synthetase family. EpmA subfamily. (325 aa) |
| | efp | Elongation factor EF-P; Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation; Belongs to the elongation factor P family. (188 aa) |
| | lysU | Lysine tRNA synthetase, inducible; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | yjbN | tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (345 aa) |
| | yjbC | 23S rRNA pseudouridine synthase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pseudouridine synthase RsuA family. (290 aa) |
| | rpoC | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1407 aa) |
| | rpoB | RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1342 aa) |
| | rplL | 50S ribosomal subunit protein L7/L12; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (121 aa) |
| | rplJ | 50S ribosomal subunit protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (165 aa) |
| | rplA | 50S ribosomal subunit protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (234 aa) |
| | rplK | 50S ribosomal subunit protein L11; Function experimentally demonstrated in the studied species; structure. (142 aa) |
| | nusG | Transcription termination factor; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Belongs [...] (181 aa) |
| | tufB | Protein chain elongation factor EF-Tu (duplicate of tufA); Function experimentally demonstrated in the studied species; factor. (394 aa) |
| | trmA | tRNA (uracil-5-)-methyltransferase; Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA). (366 aa) |
| | rpmE | 50S ribosomal subunit protein L31; Binds the 23S rRNA. (70 aa) |
| | fdhE | Formate dehydrogenase formation protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (309 aa) |
| | aslB | Regulator of arylsulfatase activity; Function of homologous gene experimentally demonstrated in an other organism; putative regulator. (411 aa) |
| | rho | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
| | gidA | Glucose-inhibited cell-division protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34. Belongs to the MnmG family. (629 aa) |
| | gidB | Methyltransferase, SAM-dependent methyltransferase, glucose-inhibited cell-division protein; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (207 aa) |
| | trmE | GTPase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (454 aa) |
| | rnpA | Protein C5 component of RNase P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (119 aa) |
| | rpmH | 50S ribosomal subunit protein L34; Function experimentally demonstrated in the studied species; structure. (46 aa) |
| | yidF | Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (165 aa) |
| | trmH | tRNA (Guanosine-2'-O-)-methyltransferase; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (229 aa) |
| | rpoZ | RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (91 aa) |
| | yicC | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (287 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (246 aa) |
| | rpmB | 50S ribosomal subunit protein L28; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bL28 family. (78 aa) |
| | rpmG | 50S ribosomal subunit protein L33; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bL33 family. (55 aa) |
| | yibK | Putative rRNA methylase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (157 aa) |
| | selA | Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (463 aa) |
| | selB | selenocysteinyl-tRNA-specific translation factor; Function experimentally demonstrated in the studied species; factor. (614 aa) |
| | glyQ | Glycine tRNA synthetase, alpha subunit; Function experimentally demonstrated in the studied species; enzyme. (303 aa) |
| | glyS | Glycine tRNA synthetase, beta subunit; Function experimentally demonstrated in the studied species; enzyme. (689 aa) |
| | yhiR | Putative DNA (exogenous) processing protein; Specifically methylates the adenine in position 2030 of 23S rRNA. (280 aa) |
| | yhiQ | Putative SAM-dependent methyltransferase; Specifically methylates the guanosine in position 1516 of 16S rRNA. (250 aa) |
| | yhiN | Putative oxidoreductase with FAD/NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (400 aa) |
| | tusA | Sulfurtransferase; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin. (81 aa) |
| | yhhF | Putative methyltransferase; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (198 aa) |
| | rpoH | RNA polymerase, sigma 32 (sigma H) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (284 aa) |
| | yhhK | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (127 aa) |
| | rtcB | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (408 aa) |
| | rtcA | RNA 3'-terminal phosphate cyclase; Function experimentally demonstrated in the studied species; enzyme. (338 aa) |
| | gntY | Putative gluconate transport associated protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (191 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (334 aa) |
| | slyD | FKBP-type peptidyl prolyl cis-trans isomerase (rotamase); Function experimentally demonstrated in the studied species; enzyme. (196 aa) |
| | tusD | Methylsulfur transfer protein; Function experimentally demonstrated in the studied species; enzyme. (128 aa) |
| | tusC | Methylsulfur transfer protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (119 aa) |
| | tusB | Methylsulfur transfer protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (95 aa) |
| | rpsL | 30S ribosomal subunit protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (124 aa) |
| | rpsG | 30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa) |
| | fusA | Protein chain elongation factor EF-G, GTP-binding; Function experimentally demonstrated in the studied species; factor. (704 aa) |
| | tufA | Protein chain elongation factor EF-Tu (duplicate of tufB); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | hopD | Putative bifunctional prepilin peptidase HopD: leader peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Belongs to the peptidase A24 family. (155 aa) |
| | rpsJ | 30S ribosomal subunit protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (103 aa) |
| | rplC | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (209 aa) |
| | rplD | 50S ribosomal subunit protein L4; Forms part of the polypeptide exit tunnel. (201 aa) |
| | rplW | 50S ribosomal subunit protein L23; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (100 aa) |
| | rplB | 50S ribosomal subunit protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (273 aa) |
| | rpsS | 30S ribosomal subunit protein S19; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS19 family. (92 aa) |
| | rplV | 50S ribosomal subunit protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (110 aa) |
| | rpsC | 30S ribosomal subunit protein S3; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (233 aa) |
| | rplP | 50S ribosomal subunit protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (136 aa) |
| | rpmC | 50S ribosomal subunit protein L29; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uL29 family. (63 aa) |
| | rpsQ | 30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa) |
| | rplN | 50S ribosomal subunit protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (123 aa) |
| | rplX | 50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (104 aa) |
| | rplE | 50S ribosomal subunit protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (179 aa) |
| | rpsN | 30S ribosomal subunit protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (101 aa) |
| | rpsH | 30S ribosomal subunit protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (130 aa) |
| | rplF | 50S ribosomal subunit protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (177 aa) |
| | rplR | 50S ribosomal subunit protein L18; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (117 aa) |
| | rpsE | 30S ribosomal subunit protein S5; Function experimentally demonstrated in the studied species; structure. (167 aa) |
| | rpmD | 50S ribosomal subunit protein L30; Function experimentally demonstrated in the studied species; structure. (59 aa) |
| | rplO | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (144 aa) |
| | rpsM | 30S ribosomal subunit protein S13; Function experimentally demonstrated in the studied species; structure. (118 aa) |
| | rpsK | 30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa) |
| | rpsD | 30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa) |
| | rpoA | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (329 aa) |
| | rplQ | 50S ribosomal subunit protein L17; Function experimentally demonstrated in the studied species; structure. (127 aa) |
| | zntR | DNA-binding transcriptional activator in response to Zn(II); Function experimentally demonstrated in the studied species; regulator. (141 aa) |
| | yhdL | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (72 aa) |
| | rsmB | 16S rRNA m5C967 methyltransferase, S-adenosyl-L-methionine-dependent; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. (429 aa) |
| | fmt | 10-formyltetrahydrofolate:L-methionyl-tRNA(fMet) N-formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (315 aa) |
| | def | Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (169 aa) |
| | yrdC | Putative ribosome maturation factor; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (190 aa) |
| | dusB | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (321 aa) |
| | rng | Ribonuclease G; Function experimentally demonstrated in the studied species; enzyme. (489 aa) |
| | rplM | 50S ribosomal subunit protein L13; Function experimentally demonstrated in the studied species; structure. (142 aa) |
| | rpsI | 30S ribosomal subunit protein S9; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS9 family. (130 aa) |
| | rpoN | RNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa) |
| | rplU | 50S ribosomal subunit protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (103 aa) |
| | rpmA | 50S ribosomal subunit protein L27; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bL27 family. (85 aa) |
| | yhbY | Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (97 aa) |
| | rrmJ | 23S rRNA methyltransferase; Function experimentally demonstrated in the studied species; enzyme. (209 aa) |
| | nusA | Transcription termination/antitermination L factor; Participates in both transcription termination and antitermination. (495 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (890 aa) |
| | rbfA | 30s ribosome binding factor; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (133 aa) |
| | truB | tRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (314 aa) |
| | rpsO | 30S ribosomal subunit protein S15; Function experimentally demonstrated in the studied species; structure. (89 aa) |
| | pnp | Polynucleotide phosphorylase/polyadenylase; Function experimentally demonstrated in the studied species; enzyme. (734 aa) |
| | yraL | Putative methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (286 aa) |
| | ygjO | Putative methyltransferase small domain; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. (378 aa) |
| | ygjH | tRNA-binding protein; Function of strongly homologous gene. (110 aa) |
| | rpoD | RNA polymerase, sigma 70 (sigma D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (613 aa) |
| | rpsU | 30S ribosomal subunit protein S21; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bS21 family. (71 aa) |
| | gcp | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (337 aa) |
| | cca | Fused tRNA nucleotidyl transferase; Function experimentally demonstrated in the studied species; enzyme. (412 aa) |
| | hybD | Maturation element for hydrogenase 2; Function of strongly homologous gene; factor. (164 aa) |
| | hybE | Hydrogenase 2-specific chaperone; Function experimentally demonstrated in the studied species; factor. (162 aa) |
| | hybF | Protein involved with the maturation of hydrogenases 1 and 2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa) |
| | hybG | Hydrogenase 2 accessory protein; Function experimentally demonstrated in the studied species; putative factor. (82 aa) |
| | pppA | Bifunctional prepilin leader peptidase and methylase; Function experimentally demonstrated in the studied species; enzyme. (269 aa) |
| | yggH | tRNA (m7G46) methyltransferase, SAM-dependent; Function experimentally demonstrated in the studied species; enzyme. (239 aa) |
| | yqgF | Holliday junction resolvase; Function of strongly homologous gene; cell process. (138 aa) |
| | yggJ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (243 aa) |
| | selA_2 | Putative transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (369 aa) |
| | ygfZ | Enzyme component involved in 2-methylthio-6-iodeadenosine formation; Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication; Belongs to the tRNA-modifying YgfZ family. (326 aa) |
| | prfB | Peptide chain release factor RF-2; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (365 aa) |
| | lysS | Lysine tRNA synthetase, constitutive; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | nudH | Nucleotide hydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (176 aa) |
| | ygdL | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (268 aa) |
| | ygdK | Putative Fe-S metabolism protein (sufE-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (147 aa) |
| | ygdE | Putative methyltransferase; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. (366 aa) |
| | truC | tRNA pseudouridine synthase; Function experimentally demonstrated in the studied species; enzyme. (260 aa) |
| | rumA | 23S rRNA (uracil-5)-methyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (433 aa) |
| | truD | Pseudoruidine synthase; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. (349 aa) |
| | hypE | Carbamoyl phosphate phosphatase, hydrogenase 3 maturation protein; Function experimentally demonstrated in the studied species; enzyme. (322 aa) |
| | hypD | Protein required for maturation of hydrogenases; Function experimentally demonstrated in the studied species; factor. (373 aa) |
| | hypC | Protein required for maturation of hydrogenases 1 and 3; Function experimentally demonstrated in the studied species; factor. (90 aa) |
| | hypB | GTP hydrolase involved in nickel liganding into hydrogenases; Function experimentally demonstrated in the studied species; enzyme. (290 aa) |
| | hypA | Protein involved in nickel insertion into hydrogenases 3; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (116 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. (876 aa) |
| | smpB | Trans-translation protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switch [...] (160 aa) |
| | rpsP | 30S ribosomal subunit protein S16; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bS16 family. (82 aa) |
| | rimM | 16S rRNA processing protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (182 aa) |
| | trmD | tRNA (guanine-1-)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (255 aa) |
| | rplS | 50S ribosomal subunit protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (115 aa) |
| | rluD | 23S rRNA pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (326 aa) |
| | yfiP | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (232 aa) |
| | yfiF | Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (345 aa) |
| | yfiC | Putative S-adenosyl-L-methionine-dependent methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (245 aa) |
| | rpoE | RNA polymerase, sigma 24 (sigma E) factor; Function experimentally demonstrated in the studied species; factor; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa) |
| | lepA | GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | lepB | Leader peptidase (signal peptidase I); Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S26 family. (324 aa) |
| | rnc | RNase III; Function experimentally demonstrated in the studied species; enzyme. (226 aa) |
| | yfhL | Ferredoxin (4Fe-4S cluster-containing protein) (fdx-like); Function of strongly homologous gene; carrier. (86 aa) |
| | CAQ99465.1 | Conserved hypothetical protein from phage origin; Homologs of previously reported genes of unknown function; extrachromosomal origin. (250 aa) |
| | tadA | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (178 aa) |
| | yfhQ | Putative methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (245 aa) |
| | yfgB | Putative Fe-S containing enzyme; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (384 aa) |
| | hisS | Histidyl tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme. (424 aa) |
| | ypfI | Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (671 aa) |
| | gltX | glutamyl-tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (471 aa) |
| | trmC | Fused 5-methylaminomethyl-2-thiouridine-forming enzyme methyltransferase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. (668 aa) |
| | truA | Pseudouridylate synthase I; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (270 aa) |
| | elaC | Binuclear zinc phosphodiesterase; Zinc phosphodiesterase, which has both exoribonuclease and endoribonuclease activities. (305 aa) |
| | rplY | 50S ribosomal subunit protein L25; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. (94 aa) |
| | yejH | Putative nucleic acid ATP-dependent helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (586 aa) |
| | rsuA | 16S rRNA pseudouridylate 516 synthase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pseudouridine synthase RsuA family. (231 aa) |
| | yeiP | Putative elongation factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the elongation factor P family. (275 aa) |
| | dusC | tRNA-dihydrouridine synthase C; Function experimentally demonstrated in the studied species; enzyme. (315 aa) |
| | metG | methionyl-tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme. (677 aa) |
| | yegP | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (110 aa) |
| | fliA | RNA polymerase, sigma 28 (sigma F) factor; Function experimentally demonstrated in the studied species; factor. (239 aa) |
| | argS | arginyl-tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme. (577 aa) |
| | yecP | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (323 aa) |
| | yecO | AdoMet-dependent methyltransferase; Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM). (247 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (590 aa) |
| | yebU | Putative RNA AdoMet-dependent methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (479 aa) |
| | yeaZ | Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (231 aa) |
| | rnd | Function experimentally demonstrated in the studied species; enzyme. (375 aa) |
| | sppA | Protease IV (signal peptide peptidase); Function experimentally demonstrated in the studied species; enzyme. (618 aa) |
| | thrS | Fragment of protein chain initiation factor IF-3 (partial); Gene remnant; factor; Belongs to the class-II aminoacyl-tRNA synthetase family. (642 aa) |
| | rpmI | 50S ribosomal subunit protein L35; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bL35 family. (65 aa) |
| | rplT | 50S ribosomal subunit protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit. (118 aa) |
| | pheS | Phenylalanine tRNA synthetase, alpha subunit; Function experimentally demonstrated in the studied species; enzyme. (327 aa) |
| | pheT | Phenylalanine tRNA synthetase, beta subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (795 aa) |
| | rnt | Ribonuclease T (RNase T); Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis. (215 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (424 aa) |
| | uidR | DNA-binding transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (196 aa) |
| | dgsA | DNA-binding transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (406 aa) |
| | dicA | Putative transcriptional regulator for DicB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (135 aa) |
| | relB | Bifunctional antitoxin of the RelE-RelB toxin-antitoxin system and transcriptional repressor; Function experimentally demonstrated in the studied species; extrachromosomal origin. (79 aa) |
| | lsrR | DNA-binding transcriptional regulator; Function experimentally demonstrated in the studied species; regulator. (317 aa) |
| | hipB | DNA-binding transcriptional regulator; Function experimentally demonstrated in the studied species; regulator. (88 aa) |
| | ydeM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative regulator. (385 aa) |
| | rimL | ribosomal-protein-L7/L12-serine acetyltransferase; Function experimentally demonstrated in the studied species; enzyme. (183 aa) |
| | hrpA | ATP-dependent helicase; Function experimentally demonstrated in the studied species; enzyme. (1281 aa) |
| | paaX | DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive; Function experimentally demonstrated in the studied species; regulator. (316 aa) |
| | ydaO | Putative C32 tRNA thiolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (311 aa) |
| | puuR | DNA-binding transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (185 aa) |
| | yciH | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (108 aa) |
| | rluB | 23S rRNA pseudouridylate synthase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pseudouridine synthase RsuA family. (299 aa) |
| | yciO | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the SUA5 family. (206 aa) |
| | yciV | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (293 aa) |
| | ychN | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (117 aa) |
| | prfA | Peptide chain release factor RF-1; Function experimentally demonstrated in the studied species; factor. (360 aa) |
| | pth | peptidyl-tRNA hydrolase; Function experimentally demonstrated in the studied species; enzyme. (194 aa) |
| | ymfC | 23S rRNA pseudouridine synthase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pseudouridine synthase RsuA family. (217 aa) |
| | trmU | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln), leading to the formation of s(2)U34, the first step of tRNA-mnm(5)s(2)U34 synthesis. Sulfur is provided by IscS, via a sulfur-relay system. Binds ATP and its substrate tRNAs; Belongs to the MnmA/TRMU family. (368 aa) |
| | rpmF | 50S ribosomal subunit protein L32; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bL32 family. (57 aa) |
| | rluC | 23S rRNA pseudouridylate synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (319 aa) |
| | rne | Fused ribonucleaseE: endoribonuclease; Function experimentally demonstrated in the studied species; enzyme. (1061 aa) |
| | rimJ | ribosomal-protein-S5-alanine N-acetyltransferase; Function experimentally demonstrated in the studied species; enzyme. (194 aa) |
| | yceA | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; ; Belongs to the UPF0176 family. (350 aa) |
| | hyaD | Protein involved in processing of HyaA and HyaB proteins; Function experimentally demonstrated in the studied species; factor. (195 aa) |
| | tusE | Subunit of enzyme for 2-thio modification of mnm5s2U of tRNA anticodon U; Function experimentally demonstrated in the studied species; factor. (109 aa) |
| | yccW | Putative AdoMet-dependent methyltransferase, UPF0064 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. (367 aa) |
| | ycbY | Putative conserved AdoMet-dependent methyltransferase with RNA interaction domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. (702 aa) |
| | asnS | Asparaginyl tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme. (466 aa) |
| | smtA | Putative AdoMet-dependent methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (261 aa) |
| | rpsA | 30S ribosomal subunit protein S1; Required for translation of most natural mRNAs except for leaderless mRNA. Binds mRNA upstream of the Shine-Dalgarno (SD) sequence and helps it bind to the 30S ribosomal subunit; acts as an RNA chaperone to unfold structured mRNA on the ribosome but is not essential for mRNAs with strong SDs and little 5'-UTR structure, thus it may help fine-tune which mRNAs that are translated. Unwinds dsRNA by binding to transiently formed ssRNA regions; binds about 10 nucleotides. Has a preference for polypyrimidine tracts. Negatively autoregulates its own translation. (557 aa) |
| | ycaN | Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (302 aa) |
| | serS | seryl-tRNA synthetase, also charges selenocysteinyl-tRNA with serine; Function experimentally demonstrated in the studied species; enzyme. (430 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | rumB | 23S rRNA m(5)U747 methyltransferase; Function experimentally demonstrated in the studied species; enzyme. (375 aa) |
| | rimK | Ribosomal protein S6 modification protein; Function experimentally demonstrated in the studied species; structure. (300 aa) |
| | ybjK | Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (178 aa) |
| | yliG | Putative AdoMet-dependent methyltransferase, UPF0004 family; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (441 aa) |
| | iaaA | Isoaspartyl dipeptidase with L-asparaginase activity; Function experimentally demonstrated in the studied species; enzyme. (321 aa) |
| | ybiN | Putative AdoMet-dependent methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. (308 aa) |
| | glnS | glutamyl-tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme. (554 aa) |
| | miaB | Isopentenyl-adenosine A37 tRNA methylthiolase; Function experimentally demonstrated in the studied species; enzyme. (474 aa) |
| | ybeY | Putative metal-dependent hydrolase; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (155 aa) |
| | leuS | leucyl-tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme. (860 aa) |
| | ybeA | Conserved hypothetical protein; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (155 aa) |
| | lipB | Lipoyl-protein ligase; Function experimentally demonstrated in the studied species; enzyme. (213 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa) |
| | ybcJ | Putative RNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (70 aa) |
| | cysS | cysteinyl-tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | ybbB | tRNA 2-selenouridine synthase, selenophosphate-dependent; Function experimentally demonstrated in the studied species; enzyme. (364 aa) |
| | ybaK | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (159 aa) |
| | bolA | Regulator of penicillin binding proteins and beta lactamase transcription (morphogene); Function experimentally demonstrated in the studied species; regulator; Belongs to the BolA/IbaG family. (105 aa) |
| | thiI | Sulfurtransferase required for thiamine and 4-thiouridine biosynthesis; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS. (482 aa) |
| | nusB | Transcription antitermination protein; Function experimentally demonstrated in the studied species; factor. (139 aa) |
| | tgt | tRNA-guanine transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the [...] (375 aa) |
| | ykgM | Putative ribosomal protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. (87 aa) |
| | prfH | Putative peptide chain release factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (166 aa) |
| | prfH-2 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (388 aa) |
| | yafQ | Toxin of the YafQ-DinJ toxin-antitoxin system; Function experimentally demonstrated in the studied species; factor. (92 aa) |
| | proS | Fragment of putative lipoprotein (part 1); Gene remnant; lipoprotein. (572 aa) |
| | yaeJ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (140 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (432 aa) |
| | hlpA | Periplasmic chaperone; Function experimentally demonstrated in the studied species; factor; Belongs to the skp family. (161 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (185 aa) |
| | tsf | Protein chain elongation factor EF-Ts; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (283 aa) |
| | rpsB | 30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family. (241 aa) |
| | hrpB | ATP-dependent (RNA) helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (809 aa) |
| | yadB | glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (308 aa) |
| | pcnB | poly(A) polymerase I; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (472 aa) |
| | mraW | S-adenosyl-dependent methyltransferase activity on membrane-located substrates; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (313 aa) |
| | rluA | Pseudouridine synthase for 23S rRNA (position 746) and tRNAphe(position 32); Function experimentally demonstrated in the studied species; enzyme. (219 aa) |
| | ksgA | S-adenosylmethionine-6-N',N'-adenosyl (rRNA) dimethyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (273 aa) |
| | caiF | Transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (131 aa) |
| | ileS | isoleucyl-tRNA synthetase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family. (938 aa) |
| | rpsT | 30S ribosomal subunit protein S20; Binds directly to 16S ribosomal RNA. (87 aa) |
