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| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Function experimentally demonstrated in the studied species; enzyme. (372 aa) |
| | ispH | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate reductase, 4Fe-4S protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. (316 aa) |
| | aceE | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding; Function experimentally demonstrated in the studied species; enzyme. (887 aa) |
| | aceF | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. (630 aa) |
| | lpd | Lipoamide dehydrogenase, E3 component is part of three enzyme complexes; Function experimentally demonstrated in the studied species; enzyme. (474 aa) |
| | panD | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine; Belongs to the PanD family. (126 aa) |
| | panC | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (283 aa) |
| | panB | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (264 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Function experimentally demonstrated in the studied species; enzyme. (398 aa) |
| | fabZ | (3R)-hydroxymyristol acyl carrier protein dehydratase; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (151 aa) |
| | accA | acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | gloB | Putative hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (251 aa) |
| | fadE | Acyl coenzyme A dehydrogenase; Function experimentally demonstrated in the studied species; enzyme. (814 aa) |
| | ykgF | Putative oxidoreductase subunit with NAD(P)-binding domain and ferridoxin-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (475 aa) |
| | ykgG | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (231 aa) |
| | yahK | Putative oxidoreductase, Zn-dependent and NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (349 aa) |
| | prpR | DNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (528 aa) |
| | prpB | 2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (296 aa) |
| | prpD | 2-methylcitrate dehydratase; Function experimentally demonstrated in the studied species; enzyme. (483 aa) |
| | prpE | propionyl-CoA synthetase; Function of homologous gene experimentally demonstrated in an other organism; putative enzyme. (628 aa) |
| | mhpA | 3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). (554 aa) |
| | mhpB | 2,3-dihydroxyphenylpropionate 1,2-dioxygenase; Function experimentally demonstrated in the studied species; enzyme. (314 aa) |
| | mhpC | 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; Function experimentally demonstrated in the studied species; enzyme. (293 aa) |
| | mhpD | 2-keto-4-pentenoate hydratase; Function experimentally demonstrated in the studied species; enzyme. (269 aa) |
| | mhpF | acetaldehyde-CoA dehydrogenase II, NAD-binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (316 aa) |
| | mhpE | 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase, class I; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (337 aa) |
| | yaiS | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (223 aa) |
| | acpH | Acyl carrier protein phosphodiesterase; Converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine prosthetic group from ACP; Belongs to the AcpH family. (193 aa) |
| | panE | 2-dehydropantoate reductase, NADPH-specific; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (303 aa) |
| | ybaW | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (132 aa) |
| | gcl | Glyoxylate carboligase; Function experimentally demonstrated in the studied species; enzyme. (593 aa) |
| | hyi | Hydroxypyruvate isomerase; Function experimentally demonstrated in the studied species; enzyme. (258 aa) |
| | glxR | Tartronate semialdehyde reductase, NADH-dependent; Function experimentally demonstrated in the studied species; enzyme. (292 aa) |
| | lipA | Lipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa) |
| | gpmA | Function experimentally demonstrated in the studied species; enzyme. (250 aa) |
| | ybhH | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (350 aa) |
| | bioA | 7,8-diaminopelargonic acid synthase, PLP-dependent; Function experimentally demonstrated in the studied species; enzyme. (429 aa) |
| | bioB | Biotin synthase; Function experimentally demonstrated in the studied species; enzyme. (346 aa) |
| | bioF | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. (384 aa) |
| | bioC | Putative methltransferase, enzyme of biotin synthesis; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. (251 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (225 aa) |
| | poxB | Pyruvate dehydrogenase (pyruvate oxidase), thiamin-dependent, FAD-binding; Function experimentally demonstrated in the studied species; enzyme; Belongs to the TPP enzyme family. (572 aa) |
| | ycbL | Putative metal-binding hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (215 aa) |
| | fabA | Beta-hydroxydecanoyl thioester dehydrase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (172 aa) |
| | plsX | Fatty acid/phospholipid synthesis protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (356 aa) |
| | hyfF | Hydrogenase 4, membrane subunit; Function experimentally demonstrated in the studied species; membrane component. (526 aa) |
| | hyfE | Hydrogenase 4, membrane subunit; Function experimentally demonstrated in the studied species; membrane component. (216 aa) |
| | hyfC | Hydrogenase 4, membrane subunit; Function experimentally demonstrated in the studied species; membrane component. (322 aa) |
| | yfeU | Putative PTS component; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. (298 aa) |
| | glk | Glucokinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the bacterial glucokinase family. (321 aa) |
| | yfcY | beta-ketoacyl-CoA thiolase, anaerobic, subunit; Function experimentally demonstrated in the studied species; enzyme. (436 aa) |
| | yfcX | Fused enoyl-CoA hydratase and epimerase and isomerase; Function experimentally demonstrated in the studied species; enzyme. (714 aa) |
| | fabB | 3-oxoacyl-[acyl-carrier-protein] synthase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (406 aa) |
| | accD | acetyl-CoA carboxylase, beta (carboxyltranferase) subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. Belongs to the AccD/PCCB family. (304 aa) |
| | dld | D-lactate dehydrogenase, FAD-binding, NADH independent; Function experimentally demonstrated in the studied species; enzyme. (571 aa) |
| | fbaB | Fructose-bisphosphate aldolase class I; Function experimentally demonstrated in the studied species; enzyme. (350 aa) |
| | gnd | Gluconate-6-phosphate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | pykA | Pyruvate kinase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pyruvate kinase family. (480 aa) |
| | edd | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa) |
| | fadD | acyl-CoA synthetase (long-chain-fatty-acid--CoA ligase); Function experimentally demonstrated in the studied species; enzyme. (561 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase A; Function experimentally demonstrated in the studied species; enzyme. (331 aa) |
| | pps | Phosphoenolpyruvate synthase; Function experimentally demonstrated in the studied species; enzyme. (792 aa) |
| | ydiD | Short chain acyl-CoA synthetase, anaerobic; Function experimentally demonstrated in the studied species; enzyme. (566 aa) |
| | ydiO | Putative acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (383 aa) |
| | aroD | 3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. (252 aa) |
| | ydiJ | Putative conserved FAD-linked oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1018 aa) |
| | pykF | Pyruvate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pyruvate kinase family. (470 aa) |
| | ydhX | Putative 4Fe-4S ferridoxin-type subunit of oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (222 aa) |
| | cfa | Cyclopropane fatty acyl phospholipid synthase (unsaturated-phospholipid methyltransferase); Function experimentally demonstrated in the studied species; enzyme. (382 aa) |
| | gloA | Glyoxalase I, Ni-dependent; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (135 aa) |
| | anmK | anhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (369 aa) |
| | hdhA | 7-alpha-hydroxysteroid dehydrogenase, NAD-dependent; Function experimentally demonstrated in the studied species; enzyme. (255 aa) |
| | ynfK | Putative synthase (similar to dethiobiotin synthetase); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (231 aa) |
| | ydfG | L-allo-threonine dehydrogenase, NAD(P)-binding; Function experimentally demonstrated in the studied species; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (248 aa) |
| | yneI | Putative aldehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (462 aa) |
| | uxaB | Altronate oxidoreductase, NAD-dependent; Function experimentally demonstrated in the studied species; enzyme. (483 aa) |
| | lsrF | Putative aldolase; Involved in the degradation of phospho-AI-2, thereby terminating induction of the lsr operon and closing the AI-2 signaling cycle. Catalyzes the transfer of an acetyl moiety from 3-hydroxy-5- phosphonooxypentane-2,4-dione to CoA to form glycerone phosphate and acetyl-CoA; Belongs to the DeoC/FbaB aldolase family. (291 aa) |
| | scoA | succinyl-CoA:3-ketoacid-coenzyme A transferase subunit A; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (235 aa) |
| | CAQ98345.1 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (307 aa) |
| | sfcA | Malate dehydrogenase, (decarboxylating, NAD-requiring) (malic enzyme); Function experimentally demonstrated in the studied species; enzyme. (565 aa) |
| | fdnH | Formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (294 aa) |
| | aldA | Aldehyde dehydrogenase A, NAD-linked; Function experimentally demonstrated in the studied species; enzyme. (479 aa) |
| | paaY | Putative hexapeptide repeat acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (196 aa) |
| | paaX | DNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive; Function experimentally demonstrated in the studied species; regulator. (316 aa) |
| | paaK | phenylacetyl-CoA ligase; Function experimentally demonstrated in the studied species; enzyme. (437 aa) |
| | paaE | Beta-ketoadipyl CoA thiolase; Catalyzes thiolytic cleavage of beta-ketoadipyl-CoA to succinyl-CoA and acetyl-CoA. (401 aa) |
| | paaI | Phenylacetate pathway hotdog-fold thioesterase; Function experimentally demonstrated in the studied species; enzyme. (140 aa) |
| | paaH | 3-hydroxybutyryl-CoA dehydrogenase; Function experimentally demonstrated in the studied species; enzyme. (475 aa) |
| | paaG | acyl-CoA hydratase; Function experimentally demonstrated in the studied species; enzyme. (262 aa) |
| | paaF | enoyl-CoA hydratase-isomerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the enoyl-CoA hydratase/isomerase family. (255 aa) |
| | paaJ | Subunit of the phenylacetly-CoA oxygenase/reductase; Function experimentally demonstrated in the studied species; enzyme. (356 aa) |
| | paaD | Putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (165 aa) |
| | paaC | Putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (248 aa) |
| | paaB | Putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (95 aa) |
| | paaA | Putative multicomponent oxygenase/reductase subunit for phenylacetic acid degradation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (309 aa) |
| | maoC | Fused aldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme. (681 aa) |
| | puuE | GABA aminotransferase, PLP-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa) |
| | fabI | Enoyl-[acyl-carrier-protein] reductase, NADH-dependent; Function experimentally demonstrated in the studied species; enzyme. (262 aa) |
| | yciA | Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (132 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methylerythritol kinase; Function experimentally demonstrated in the studied species; enzyme. (283 aa) |
| | fadR | DNA-binding transcriptional dual regulator of fatty acid metabolism; Multifunctional regulator of fatty acid metabolism. (239 aa) |
| | ycgM | Putative isomerase/hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (219 aa) |
| | icd | Isocitrate dehydrogenase, specific for NADP+; Function experimentally demonstrated in the studied species; extrachromosomal origin. (416 aa) |
| | fabF | 3-oxoacyl-[acyl-carrier-protein] synthase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (413 aa) |
| | acpP | Acyl carrier protein (ACP); Function experimentally demonstrated in the studied species; carrier. (78 aa) |
| | fabH | 3-oxoacyl-[acyl-carrier-protein] synthase III; Function experimentally demonstrated in the studied species; enzyme. (317 aa) |
| | fabG | 3-oxoacyl-[acyl-carrier-protein] reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa) |
| | fabD | malonyl-CoA-[acyl-carrier-protein] transacylase; Function experimentally demonstrated in the studied species; enzyme. (309 aa) |
| | ytjC | Phosphoglyceromutase 2, co-factor independent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
| | yjjN | Putative oxidoreductase, Zn-dependent and NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (340 aa) |
| | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Decarboxylates OPET (5-oxo-pent-3-ene-1,2,5-tricarboxylic acid) into HHDD (2-hydroxy-hept-2,4-diene-1,7-dioate) and isomerizes it to OHED (2-oxo-hept-3-ene-1,7-dioate). (431 aa) |
| | hpaE | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Transforms 5-carboxymethyl-2-hydroxy-muconic semialdehyde (CHMS) into 5-carboxymethyl-2-hydroxy-muconic acid (CHM); Belongs to the aldehyde dehydrogenase family. (488 aa) |
| | hpaI | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinate semialdehyde. Is also able to catalyze the aldol cleavage of 4-hydroxy-2- ketopentanoate and 4-hydroxy-2-ketohexanoate. Is not stereospecific since it can cleave both substrate enantiomers. Also exhibits significant oxaloacetate decarboxylase activity in vitro. In the reverse direction, is able to condense a range of aldehyde acceptors (from two to five carbons in length) with pyruvate or 2-oxobutanoate. Unlike with BphI [...] (309 aa) |
| | hpaB | 4-hydroxyphenylacetate 3-monooxygenase large component; Utilizes FADH(2) supplied by HpaC or by another flavin reductase, to catalyze the hydroxylation of 4-hydroxyphenylacetic acid, leading to the production of 3,4-DHPA. Can also oxidize phenol to catechol, and hydroxylate other phenol derivatives. Belongs to the FADH(2)-utilizing monooxygenase family. (520 aa) |
| | uxuA | Mannonate hydrolase; Catalyzes the dehydration of D-mannonate. (394 aa) |
| | gntP | Fructuronate transporter; Function experimentally demonstrated in the studied species; transporter. (447 aa) |
| | yjgB | Putative alcohol dehydrogenase, Zn-dependent and NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (339 aa) |
| | yjeK | Putative lysine aminomutase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (342 aa) |
| | fdhF | Formate dehydrogenase-H, selenopolypeptide subunit; Function experimentally demonstrated in the studied genus; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (715 aa) |
| | nrfC | Formate-dependent nitrite reductase, 4Fe4S subunit; Function experimentally demonstrated in the studied species; carrier. (223 aa) |
| | acs | acetyl-CoA synthetase; Function experimentally demonstrated in the studied species; enzyme. (652 aa) |
| | ubiC | Chorismate pyruvate lyase; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. (165 aa) |
| | pgi | Glucosephosphate isomerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the GPI family. (549 aa) |
| | aceK | Isocitrate dehydrogenase kinase/phosphatase; Function experimentally demonstrated in the studied species; enzyme. (578 aa) |
| | aceA | Isocitrate lyase; Function experimentally demonstrated in the studied species; enzyme. (434 aa) |
| | aceB | Malate synthase A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the malate synthase family. (533 aa) |
| | fabR | DNA-binding transcriptional repressor; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer. (234 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | pfkA | 6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | fdoH | Formate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa) |
| | yiiD | Putative acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (329 aa) |
| | fadB | Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (729 aa) |
| | fadA | 3-ketoacyl-CoA thiolase (thiolase I); Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa) |
| | dgoK | 2-oxo-3-deoxygalactonate kinase; Function experimentally demonstrated in the studied species; enzyme. (292 aa) |
| | dgoA | 2-oxo-3-deoxygalactonate 6-phosphate aldolase; Function experimentally demonstrated in the studied species; enzyme. (205 aa) |
| | dgoD | Galactonate dehydratase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (382 aa) |
| | yidR | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (404 aa) |
| | dfp | Fused 4'-phosphopantothenoylcysteine decarboxylase; Function experimentally demonstrated in the studied species; enzyme. (406 aa) |
| | gpmI | Phosphoglycero mutase III, cofactor-independent; Function experimentally demonstrated in the studied species; enzyme. (514 aa) |
| | lldD | L-lactate dehydrogenase, FMN-linked; Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain; Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family. (396 aa) |
| | tiaE | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Function experimentally demonstrated in the studied species; enzyme. (324 aa) |
| | yhhK | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (127 aa) |
| | gntU | Gluconate transporter, low affinity GNT 1 system; Function experimentally demonstrated in the studied species; transporter. (446 aa) |
| | bioH | Carboxylesterase of pimeloyl-CoA synthesis; Function experimentally demonstrated in the studied species; enzyme. (256 aa) |
| | gph | Phosphoglycolate phosphatase; Function experimentally demonstrated in the studied species; enzyme. (252 aa) |
| | yheT | Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (340 aa) |
| | slyX | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the SlyX family. (72 aa) |
| | aroE | Dehydroshikimate reductase, NAD(P)-binding; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; Function experimentally demonstrated in the studied species; enzyme. (449 aa) |
| | accB | Acetyl CoA carboxylase, BCCP subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa) |
| | yhbO | Putative intracellular protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (172 aa) |
| | garR | Tartronate semialdehyde reductase; Function experimentally demonstrated in the studied species; enzyme. (296 aa) |
| | tdcA | DNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (312 aa) |
| | tdcB | Catabolic threonine dehydratase, PLP-dependent; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (329 aa) |
| | tdcD | Propionate kinase/acetate kinase C, anaerobic; Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP. (406 aa) |
| | tdcF | L-PSP (mRNA) endoribonuclease; Function of strongly homologous gene; enzyme. (129 aa) |
| | yhaM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0597 family. (436 aa) |
| | uxaC | Uronate isomerase; Function experimentally demonstrated in the studied species; enzyme. (470 aa) |
| | uxaA | Altronate hydrolase; Function experimentally demonstrated in the studied species; enzyme. (495 aa) |
| | fadH | 2,4-dienoyl-CoA reductase, NADH and FMN-linked; Function experimentally demonstrated in the studied species; enzyme. (672 aa) |
| | hybB | Function of strongly homologous gene; carrier. (392 aa) |
| | CAQ99941.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (82 aa) |
| | glcD | Glycolate oxidase subunit, FAD-linked; Function experimentally demonstrated in the studied species; enzyme. (499 aa) |
| | glcE | Glycolate oxidase FAD binding subunit; Function experimentally demonstrated in the studied species; enzyme. (350 aa) |
| | glcF | Glycolate oxidase iron-sulfur subunit; Function experimentally demonstrated in the studied species; carrier. (407 aa) |
| | glcB | Malate synthase G; Function experimentally demonstrated in the studied species; enzyme. (723 aa) |
| | pgk | Phosphoglycerate kinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | ygfH | propionyl-CoA:succinate-CoA transferase; Function experimentally demonstrated in the studied species; enzyme. (492 aa) |
| | ygfG | methylmalonyl-CoA decarboxylase, biotin-independent; Function experimentally demonstrated in the studied species; enzyme. (261 aa) |
| | yliK | methylmalonyl-CoA mutase; Function experimentally demonstrated in the studied species; enzyme. (714 aa) |
| | kduD | 2-deoxy-D-gluconate 3-dehydrogenase; Function experimentally demonstrated in the studied species; enzyme. (253 aa) |
| | aas | Fused 2-acylglycerophospho-ethanolamine acyl transferase; Function experimentally demonstrated in the studied species; enzyme. (719 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa) |
| | ygcU | Putative FAD containing dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (484 aa) |
| | ispD | 4-diphosphocytidyl-2C-methyl-D-erythritol synthase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (236 aa) |
| | ispF | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (159 aa) |
| | ygbM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the hyi family. (258 aa) |
| | hycB | Hydrogenase 3, Fe-S subunit; Function experimentally demonstrated in the studied species; carrier. (203 aa) |
| | hycD | Hydrogenase 3, membrane subunit; Function experimentally demonstrated in the studied species; membrane component. (307 aa) |
| | hycF | Formate hydrogenlyase complex iron-sulfur protein; Function experimentally demonstrated in the studied species; carrier. (180 aa) |
| | gabT | 4-aminobutyrate aminotransferase, PLP-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | gabD | Succinate-semialdehyde dehydrogenase I, NADP-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aldehyde dehydrogenase family. (482 aa) |
| | acpS | Holo-[acyl-carrier-protein] synthase 1; Function experimentally demonstrated in the studied species; enzyme. (126 aa) |
| | hcaB | 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Converts 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol) into 3-(2,3- dihydroxylphenyl)propanoic acid (DHPP) and 2,3-dihydroxicinnamic acid (DHCI), respectively; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa) |
| | hcaC | 3-phenylpropionate dioxygenase, putative ferredoxin subunit; Function experimentally demonstrated in the studied species; putative carrier. (106 aa) |
| | hcaF | 3-phenylpropionate dioxygenase, small (beta) subunit; Function experimentally demonstrated in the studied species; enzyme. (172 aa) |
| | hcaE | 3-phenylpropionate dioxygenase, large (alpha) subunit; Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively; Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. (453 aa) |
