(5 nodes) Lipoprotein transport network (Escherichia coli IAI1)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ybbA	Putative transporter subunit: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (228 aa)
	lolE	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter. (414 aa)
	lolD	Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. (233 aa)
	lolC	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter. (399 aa)
	lolA	Chaperone for lipoproteins; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (204 aa)

Your Current Organism:

Escherichia coli IAI1

NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
lolA	lolC	ECIAI1_0931	ECIAI1_1153	Chaperone for lipoproteins; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	0.997
lolA	lolD	ECIAI1_0931	ECIAI1_1154	Chaperone for lipoproteins; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.978
lolA	lolE	ECIAI1_0931	ECIAI1_1155	Chaperone for lipoproteins; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	0.994
lolC	lolA	ECIAI1_1153	ECIAI1_0931	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	Chaperone for lipoproteins; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.997
lolC	lolD	ECIAI1_1153	ECIAI1_1154	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.999
lolC	lolE	ECIAI1_1153	ECIAI1_1155	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	0.999
lolD	lolA	ECIAI1_1154	ECIAI1_0931	Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	Chaperone for lipoproteins; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.978
lolD	lolC	ECIAI1_1154	ECIAI1_1153	Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	0.999
lolD	lolE	ECIAI1_1154	ECIAI1_1155	Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	0.999
lolE	lolA	ECIAI1_1155	ECIAI1_0931	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	Chaperone for lipoproteins; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).	0.994
lolE	lolC	ECIAI1_1155	ECIAI1_1153	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	0.999
lolE	lolD	ECIAI1_1155	ECIAI1_1154	Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter.	Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner.	0.999