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| | yjhT | Conserved hypothetical protein; Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta- anomer, accelerating the equilibrium between the alpha- and beta- anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses; Belongs to the NanM family. (368 aa) |
| | htrE_2 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (103 aa) |
| | CAQ96912.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (83 aa) |
| | surA | Peptidyl-prolyl cis-trans isomerase (PPIase); Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation. (428 aa) |
| | imp | Exported protein required for envelope biosynthesis and integrity; Function experimentally demonstrated in the studied species; factor. (784 aa) |
| | tbpA | Thiamin transporter subunit; Function experimentally demonstrated in the studied species; transporter. (327 aa) |
| | sgrR | DNA-binding transcriptional regulator; Function experimentally demonstrated in the studied species; regulator. (551 aa) |
| | cueO | Multicopper oxidase (laccase); Function experimentally demonstrated in the studied species; enzyme. (516 aa) |
| | htrE | Outer membrane usher protein; Function of strongly homologous gene; factor. (866 aa) |
| | ecpD | Periplasmic pilin chaperone; Function of strongly homologous gene; factor. (246 aa) |
| | mrcB | Fused glycosyl transferase; Function experimentally demonstrated in the studied species; enzyme. (844 aa) |
| | fhuA | Ferrichrome outer membrane transporter; Function experimentally demonstrated in the studied species; transporter. (747 aa) |
| | fhuD | Iron-hydroxamate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (296 aa) |
| | btuF | Vitamin B12 transporter subunit: periplasmic-binding component of ABC superfamily; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (266 aa) |
| | degP | Serine endoprotease (protease Do), membrane-associated; Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S1C family. (474 aa) |
| | yaeT | Outer membrane protein assembly factor; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. (810 aa) |
| | nlpE | Lipoprotein involved with copper homeostasis and adhesion; Function experimentally demonstrated in the studied species; lipoprotein. (236 aa) |
| | rcsF | Conserved hypothetical protein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. (134 aa) |
| | ivy | Inhibitor of vertebrate C-lysozyme; Function experimentally demonstrated in the studied species; regulator. (157 aa) |
| | yagV | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (236 aa) |
| | yagX | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (841 aa) |
| | yagY | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (222 aa) |
| | yaiO | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (257 aa) |
| | yaiW | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (364 aa) |
| | phoA | Bacterial alkaline phosphatase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the alkaline phosphatase family. (471 aa) |
| | ybaV | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (123 aa) |
| | ybaE | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (566 aa) |
| | acrB | Multidrug efflux system protein; Function experimentally demonstrated in the studied species; transporter. (1049 aa) |
| | acrA | Multidrug efflux system; Function experimentally demonstrated in the studied species; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (397 aa) |
| | ushA | Bifunctional UDP-sugar hydrolase and 5'-nucleotidase; Function experimentally demonstrated in the studied species; enzyme. (550 aa) |
| | ybaP | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (264 aa) |
| | tesA | Multifunctional acyl-CoA thioesterase I and protease I and lysophospholipase L1; Function experimentally demonstrated in the studied species; enzyme. (208 aa) |
| | sfmC | Pilin chaperone, periplasmic; Function experimentally demonstrated in the studied species; factor. (230 aa) |
| | sfmD | Putative outer membrane export usher protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (869 aa) |
| | nfrA | Bacteriophage N4 receptor, outer membrane subunit; Function experimentally demonstrated in the studied species; membrane component. (990 aa) |
| | cusC | Copper/silver efflux system, outer membrane component; Function experimentally demonstrated in the studied species; transporter. (460 aa) |
| | cusB | Copper/silver efflux system, membrane fusion protein; Function experimentally demonstrated in the studied species; transporter. (407 aa) |
| | fepA | Iron-enterobactin outer membrane transporter; Function experimentally demonstrated in the studied species; transporter. (746 aa) |
| | fepB | Iron-enterobactin transporter subunit; Function experimentally demonstrated in the studied species; transporter. (318 aa) |
| | dsbG | Periplasmic disulfide isomerase/thiol-disulphide oxidase; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (248 aa) |
| | rna | Function experimentally demonstrated in the studied species; enzyme; Belongs to the RNase T2 family. (268 aa) |
| | crcA | Palmitoyl transferase for Lipid A; Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors. (186 aa) |
| | dacA | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S11 family. (403 aa) |
| | rlpA | Minor lipoprotein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (362 aa) |
| | rlpB | Minor lipoprotein; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane. (193 aa) |
| | gltI | Glutamate and aspartate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (302 aa) |
| | lnt | Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (512 aa) |
| | kdpD | Fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein; Function experimentally demonstrated in the studied species; regulator. (894 aa) |
| | ybgP | Putative exported chaperone, PapD family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (251 aa) |
| | ybgQ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (833 aa) |
| | tolQ | Membrane spanning protein in TolA-TolQ-TolR complex; Function experimentally demonstrated in the studied species; membrane component. (230 aa) |
| | tolB | Periplasmic protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. (430 aa) |
| | pal | Peptidoglycan-associated outer membrane lipoprotein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. (173 aa) |
| | ybgF | Putative RNA binding protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family. (263 aa) |
| | ybhT | Conserved hypothetical protein; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. (49 aa) |
| | modA | Molybdate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (257 aa) |
| | ybhC | Pectin methylesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (427 aa) |
| | fiu | Putative TonB-dependent iron outer membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (760 aa) |
| | glnH | Glutamine transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the bacterial solute-binding protein 3 family. (248 aa) |
| | ompX | Outer membrane protein; Function experimentally demonstrated in the studied species; membrane component. (171 aa) |
| | ybiS | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 9298646. (306 aa) |
| | yliB | Putative peptide transporter subunit: periplasmic-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (512 aa) |
| | yliI | PQQ-dependent aldose sugar dehydrogenase precursor (asd); Function experimentally demonstrated in the studied species; enzyme. (371 aa) |
| | dacC | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 6a); Function experimentally demonstrated in the studied species; enzyme. (400 aa) |
| | potF | Putrescine transporter subunit: periplasmic-binding component of ABC superfamily; Function experimentally demonstrated in the studied species; transporter. (370 aa) |
| | artJ | Arginine transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the bacterial solute-binding protein 3 family. (243 aa) |
| | artI | Arginine transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the bacterial solute-binding protein 3 family. (243 aa) |
| | ybjP | Conserved hypothetical protein, putative exported protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (171 aa) |
| | lolA | Chaperone for lipoproteins; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). (204 aa) |
| | ycaL | Putative lipoprotein with metallohydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (254 aa) |
| | ycbK | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (182 aa) |
| | ompF | Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter. (362 aa) |
| | ycbR | Putative periplasmic pilin chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (233 aa) |
| | ycbS | Putative outer membrane export usher protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (866 aa) |
| | ycbF | Putative periplasmic pilin chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (236 aa) |
| | pqiB | Paraquat-inducible protein B; Function experimentally demonstrated in the studied species; cell process. (546 aa) |
| | ymbA | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (182 aa) |
| | hyaB | Hydrogenase 1, large subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (597 aa) |
| | appA | Phosphoanhydride phosphorylase; Function experimentally demonstrated in the studied species; enzyme. (432 aa) |
| | ymcA | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (698 aa) |
| | torC | Trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the TorC/TorY family. (390 aa) |
| | agp | Fragment of conserved hypothetical protein (part 2); Gene remnant. (413 aa) |
| | efeB | Heme-binding periplasmic protein involved in iron transport; Function experimentally demonstrated in the studied species; transporter. (423 aa) |
| | csgG | Putative outer membrane lipoprotein involved in curli production assembly/transport; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (277 aa) |
| | csgF | Putative transport/assembly protein for curli synthesis; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (138 aa) |
| | csgE | Putative transport/assembly protein for curli synthesis; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (129 aa) |
| | yceK | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (75 aa) |
| | flgG | Flagellar component of cell-distal portion of basal-body rod; Function experimentally demonstrated in the studied species; structure; Belongs to the flagella basal body rod proteins family. (260 aa) |
| | fhuE | Ferric-rhodotorulic acid outer membrane transporter; Function experimentally demonstrated in the studied species; transporter. (729 aa) |
| | ycfM | Putative outer membrane lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (213 aa) |
| | ycfJ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 7984428. (179 aa) |
| | ycfR | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (85 aa) |
| | lolC | Outer membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter. (399 aa) |
| | potD | Polyamine transporter subunit; Required for the activity of the bacterial periplasmic transport system of putrescine; Belongs to the bacterial solute-binding protein PotD/PotF family. (348 aa) |
| | ymgD | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (109 aa) |
| | emtA | Lytic murein endotransglycosylase E; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. Preferentially cleaves at a distance of more than two disaccharide units from the ends of the glycan chain. (203 aa) |
| | treA | Periplasmic trehalase; Function experimentally demonstrated in the studied species; enzyme. (565 aa) |
| | lolB | Chaperone for lipoproteins; Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein. (207 aa) |
| | oppA | Oligopeptide transporter subunit; Function experimentally demonstrated in the studied species; transporter. (543 aa) |
| | tonB | Membrane spanning protein in TonB-ExbB-ExbD complex; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (239 aa) |
| | ompW | Outer membrane protein W; Function experimentally demonstrated in the studied species; membrane component. (212 aa) |
| | pgpB | Function experimentally demonstrated in the studied species; enzyme. (254 aa) |
| | osmB | Lipoprotein; Function experimentally demonstrated in the studied species; lipoprotein. (72 aa) |
| | pspE | Thiosulfate:cyanide sulfurtransferase (rhodanese); Function experimentally demonstrated in the studied species; enzyme. (104 aa) |
| | ompG | Outer membrane porin; Function experimentally demonstrated in the studied species; transporter. (301 aa) |
| | mppA | Murein tripeptide (L-ala-gamma-D-glutamyl-meso-DAP) transporter subunit; Function experimentally demonstrated in the studied species; transporter. (537 aa) |
| | ompN | Outer membrane pore protein N, non-specific; Function experimentally demonstrated in the studied species; transporter. (377 aa) |
| | hslJ | Heat-inducible protein; Function experimentally demonstrated in the studied species; factor. (140 aa) |
| | mdoD | Glucan biosynthesis protein, periplasmic; Function experimentally demonstrated in the studied species; enzyme. (541 aa) |
| | ydcS | Putative spermidine/putrescine transporter subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (381 aa) |
| | yncD | Putative iron outer membrane receptor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative receptor. (700 aa) |
| | fdnG | Formate dehydrogenase-N, alpha subunit, nitrate-inducible; Function experimentally demonstrated in the studied genus; enzyme. (1015 aa) |
| | ddpA | D-ala-D-a la transporter subunit; Function experimentally demonstrated in the studied species; transporter. (516 aa) |
| | yddW | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (439 aa) |
| | pqqL | Putative membrane-associated peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (931 aa) |
| | yddB | Putative porin protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (790 aa) |
| | ydeN | Putative sulfatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (560 aa) |
| | fimD_3 | Putative fimbrial outer membrane usher protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (883 aa) |
| | focC_1 | Periplasmic chaperone precursor; Function of strongly homologous gene; factor. (239 aa) |
| | marB | Conserved hypothetical protein associated with multiple antibiotic resistance operon; Homologs of previously reported genes of unknown function. (72 aa) |
| | dcp | Dipeptidyl carboxypeptidase II; Function experimentally demonstrated in the studied species; enzyme. (681 aa) |
| | ynfB | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0482 family. (113 aa) |
| | asr | Acid shock-inducible periplasmic protein; Required for growth and/or survival at acidic conditions. (102 aa) |
| | uidC | Outer membrane porin protein for glucuronides transport; Function experimentally demonstrated in the studied species; transporter. (421 aa) |
| | rsxG | Putative oxidoreductase; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Required to maintain the reduced state of SoxR; Belongs to the RnfG family. (206 aa) |
| | ydhA | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (109 aa) |
| | slyB | Putative outer membrane lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (155 aa) |
| | sodC | Superoxide dismutase, Cu, Zn; Function experimentally demonstrated in the studied species; enzyme. (173 aa) |
| | ydhX | Putative 4Fe-4S ferridoxin-type subunit of oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (222 aa) |
| | osmE | DNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (112 aa) |
| | spy | Envelope stress induced periplasmic protein; Function experimentally demonstrated in the studied species; cell process. (161 aa) |
| | mipA | Scaffolding protein for murein synthesizing machinery; Function experimentally demonstrated in the studied species; factor. (248 aa) |
| | prc | Carboxy-terminal protease for penicillin-binding protein 3; Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S41A family. (682 aa) |
| | yebT | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (877 aa) |
| | yobA | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (124 aa) |
| | CAQ98787.1 | Arabinogalactan oligomer / maltooligosaccharide transport system substrate-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (440 aa) |
| | lpxM | Myristoyl-acyl carrier protein (ACP)-dependent acyltransferase; Function experimentally demonstrated in the studied species; enzyme. (323 aa) |
| | torZ | Trimethylamine N-oxide reductase system III, catalytic subunit; Function experimentally demonstrated in the studied species; enzyme. (809 aa) |
| | araF | L-arabinose transporter subunit; Function experimentally demonstrated in the studied species; transporter. (329 aa) |
| | fliY | Cystine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (266 aa) |
| | yedV | Sensory kinase in two-component regulatory system with YedW; Function experimentally demonstrated in the studied species; receptor. (452 aa) |
| | yedY | Exported heme-molybdoenzyme molybdopterin-containing subunit YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation, including the primary periplasmic chaperone [...] (334 aa) |
| | yodA | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 12480884, 12909634, 9579078. (216 aa) |
| | dacD | D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 6b); Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S11 family. (388 aa) |
| | cpsB | Mannose-1-phosphate guanylyltransferase (GDP); Involved in GDP-mannose biosynthesis which serves as the activated sugar nucleotide precursor for mannose residues in cell surface polysaccharides. This enzyme participates in synthesis of the LPS O9 antigen. (471 aa) |
| | yohN | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (172 aa) |
| | yehB | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (826 aa) |
| | yehC | Putative membrane-associated pilin chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (224 aa) |
| | yehZ | Putative transporter subunit: periplasmic-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (305 aa) |
| | bglX | beta-D-glucoside glucohydrolase, periplasmic; Function experimentally demonstrated in the studied species; enzyme. (765 aa) |
| | yohG | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (362 aa) |
| | mglB | Methyl-galactoside transporter subunit; Function experimentally demonstrated in the studied species; transporter. (332 aa) |
| | cirA | Ferric iron-catecholate outer membrane transporter; Function experimentally demonstrated in the studied species; membrane component. (663 aa) |
| | yejA | Putative oligopeptide transporter subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (604 aa) |
| | eco | Ecotin, a serine protease inhibitor; General inhibitor of pancreatic serine proteases: inhibits chymotrypsin, trypsin, elastases, factor X, kallikrein as well as a variety of other proteases. (162 aa) |
| | ompC | Outer membrane porin protein C; Function experimentally demonstrated in the studied species; transporter. (367 aa) |
| | rcsC | Hybrid sensory kinase in two-component regulatory system with RcsB and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB (By similarity). Involved in regulation of K30 capsular polysaccharide synthesis. (933 aa) |
| | yfaZ | Putative outer membrane porin protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (180 aa) |
| | hisJ | Histidine/lysine/arginine/ornithine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (260 aa) |
| | mepA | Murein DD-endopeptidase; Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus. Belongs to the peptidase M74 family. (274 aa) |
| | yfcS | Putative periplasmic pilus exported chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (250 aa) |
| | papC | Putative outer membrane usher protein yfcU precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (880 aa) |
| | fadL | Long-chain fatty acid outer membrane transporter; Function experimentally demonstrated in the studied species; transporter. (448 aa) |
| | emrK | EmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component; Function experimentally demonstrated in the studied species; transporter. (387 aa) |
| | cysP | Thiosulfate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (338 aa) |
| | amiA | N-acetylmuramoyl-l-alanine amidase I; Function experimentally demonstrated in the studied species; enzyme. (289 aa) |
| | nlpB | Lipoprotein; Function experimentally demonstrated in the studied species; lipoprotein. (344 aa) |
| | yfgC | Putative peptidase; Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state. (487 aa) |
| | yfgH | Putative outer membrane lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (172 aa) |
| | yfgL | Protein assembly complex, lipoprotein component; Function of strongly homologous gene; lipoprotein. (392 aa) |
| | yfhG | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (237 aa) |
| | yfhD | Putative transglycosylase; Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella. (472 aa) |
| | CAQ99471.1 | Conserved hypothetical protein from bacteriophage origin; Homologs of previously reported genes of unknown function; extrachromosomal origin. (668 aa) |
| | rseB | Anti-sigma factor; Function experimentally demonstrated in the studied species; factor. (318 aa) |
| | yfiO | Putative lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamA, the core component of the assembly machinery. (245 aa) |
| | yfiB | Putative outer membrane lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (160 aa) |
| | smpA | Small membrane lipoprotein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. (113 aa) |
| | proX | Glycine betaine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (330 aa) |
| | emrA | Multidrug efflux system; Function experimentally demonstrated in the studied species; transporter. (390 aa) |
| | mltB | Membrane-bound lytic murein transglycosylase B; Function experimentally demonstrated in the studied species; enzyme. (361 aa) |
| | nlpD | Fragment of RNA polymerase, sigma S (sigma 38) factor (part 1); Gene remnant; factor. (379 aa) |
| | iap | Aminopeptidase in alkaline phosphatase isozyme conversion; Function experimentally demonstrated in the studied species; enzyme. (345 aa) |
| | mltA | Membrane-bound lytic murein transglycosylase A; Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division. (365 aa) |
| | amiC | N-acetylmuramoyl-L-alanine amidase; Function experimentally demonstrated in the studied species; enzyme. (417 aa) |
| | ppdB | Prepilin peptidase-dependent protein B; Function of strongly homologous gene; enzyme. (187 aa) |
| | dsbC | Protein disulfide isomerase II; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (236 aa) |
| | yggG | Putative peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (252 aa) |
| | ansB | Periplasmic L-asparaginase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the asparaginase 1 family. (348 aa) |
| | mltC | Membrane-bound lytic murein transglycosylase C; Function experimentally demonstrated in the studied species; enzyme. (359 aa) |
| | yghE | Putative secretion pathway protein, L-type protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (392 aa) |
| | yghG | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (136 aa) |
| | sufI | Repressor protein for FtsI; Function experimentally demonstrated in the studied species; regulator. (470 aa) |
| | tolC | Transport channel; Function experimentally demonstrated in the studied species; transporter. (493 aa) |
| | ygiB | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component; Belongs to the UPF0441 family. (191 aa) |
| | yqiG | Outer membrane usher protein; Function of strongly homologous gene; factor. (837 aa) |
| | yqiH | Periplasmic pilin chaperone; Function of strongly homologous gene; factor. (249 aa) |
| | eafC | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (900 aa) |
| | CAR00057.1 | Putative fimbrial protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. (238 aa) |
| | yraI | Periplasmic pilin chaperone (lpfB-like); Function of strongly homologous gene; factor. (231 aa) |
| | yraJ | Putative outer membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (838 aa) |
| | yraM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (678 aa) |
| | ecfH | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (191 aa) |
| | yrbC | Toluene transporter subunit: membrane component of ABC superfamily; Function of strongly homologous gene; transporter. (211 aa) |
| | yrbK | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (191 aa) |
| | lptA | Putative lipopolysaccharide transport protein A: periplasmic-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (185 aa) |
| | aapJ | Amino-acid transporter subunit; Function of strongly homologous gene; transporter; Belongs to the bacterial solute-binding protein 3 family. (305 aa) |
| | fkpA | FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase); Function experimentally demonstrated in the studied species; enzyme. (270 aa) |
| | ppiA | Peptidyl-prolyl cis-trans isomerase A (rotamase A); PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (190 aa) |
| | hofQ | Fimbrial transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter. (412 aa) |
| | yrfC | Putative fimbrial assembly protein (pilN-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. (179 aa) |
| | yrfD | Putative pilus assembly protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (259 aa) |
| | envZ | Sensory histidine kinase in two-component regulatory system with OmpR; Function experimentally demonstrated in the studied species; regulator. (450 aa) |
| | ggt | Gamma-glutamyltranspeptidase; Function experimentally demonstrated in the studied species; enzyme. (580 aa) |
| | ugpB | Glycerol-3-phosphate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (438 aa) |
| | livK | Leucine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (369 aa) |
| | livJ | Leucine/isoleucine/valine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (367 aa) |
| | ftsX | Transporter subunit: membrane component of ABC superfamily; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (352 aa) |
| | yhhM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (119 aa) |
| | nikA | Nickel transporter subunit; Function experimentally demonstrated in the studied species; transporter. (524 aa) |
| | hdeB | Acid-resistance protein; Required for optimal acid stress protection, which is important for survival of enteric bacteria in the acidic environment of the host stomach. Exhibits a chaperone-like activity at acidic pH by preventing the aggregation of many different periplasmic proteins. Belongs to the HdeB family. (108 aa) |
| | treF | Cytoplasmic trehalase; Function experimentally demonstrated in the studied species; enzyme. (549 aa) |
| | yhjJ | Putative zinc-dependent peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (498 aa) |
| | dppA | Dipeptide transporter; Function experimentally demonstrated in the studied species; transporter. (535 aa) |
| | lpfC | Outer membrane usher protein lpfC precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component. (843 aa) |
| | lpfB | Chaperone protein lpfB precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component. (228 aa) |
| | bisC | Biotin sulfoxide reductase; Function experimentally demonstrated in the studied species; enzyme. (759 aa) |
| | yiaD | Putative outer membrane lipoprotien; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (219 aa) |
| | xylF | D-xylose transporter subunit; Function experimentally demonstrated in the studied species; transporter. (330 aa) |
| | malS | Alpha-amylase; Function experimentally demonstrated in the studied species; enzyme. (676 aa) |
| | yiaT | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (246 aa) |
| | envC | Protease with a role in cell division; Function experimentally demonstrated in the studied species; cell process. (419 aa) |
| | yidQ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (110 aa) |
| | pstS | Phosphate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (346 aa) |
| | lpfC-2 | Putative fimbrial usher; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (840 aa) |
| | lfpB | Putative fimbrial chaperone protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (243 aa) |
| | rbsB | D-ribose transporter subunit; Function experimentally demonstrated in the studied species; transporter. (296 aa) |
| | rfe | UDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (367 aa) |
| | pldA | Outer membrane phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. (289 aa) |
| | dsbA | Periplasmic protein disulfide isomerase I; Function experimentally demonstrated in the studied species; enzyme. (208 aa) |
| | cpxA | Sensory histidine kinase in two-component regulatory system with CpxR; Function experimentally demonstrated in the studied species; regulator. (457 aa) |
| | cpxP | Periplasmic protein combats stress; Function experimentally demonstrated in the studied species; regulator. (166 aa) |
| | sbp | Sulfate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (329 aa) |
| | zraP | Zn-binding periplasmic protein; Function experimentally demonstrated in the studied species; putative factor. (141 aa) |
| | yjbH | Putative porin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (698 aa) |
| | malE | Maltose transporter subunit; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. (396 aa) |
| | malM | Maltose regulon periplasmic protein; Function experimentally demonstrated in the studied species; putative transporter. (306 aa) |
| | aphA | Acid phosphatase/phosphotransferase, class B, non-specific; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class B bacterial acid phosphatase family. (237 aa) |
| | nrfA | Nitrite reductase, formate-dependent, cytochrome; Function experimentally demonstrated in the studied species; carrier; Belongs to the cytochrome c-552 family. (478 aa) |
| | nrfB | Nitrite reductase, formate-dependent, penta-heme cytochrome c; Function experimentally demonstrated in the studied species; carrier. (188 aa) |
| | nrfC | Formate-dependent nitrite reductase, 4Fe4S subunit; Function experimentally demonstrated in the studied species; carrier. (223 aa) |
| | yjcP | Outer membrane factor of efflux pump; Function of strongly homologous gene; putative transporter. (488 aa) |
| | yjcS | Putative alkyl sulfatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (661 aa) |
| | dcuS | Two-component system sensor histidine kinase DcuS; Function experimentally demonstrated in the studied species; regulator. (543 aa) |
| | blc | Outer membrane lipoprotein (lipocalin); Involved in the storage or transport of lipids necessary for membrane maintenance under stressful conditions. Displays a binding preference for lysophospholipids. (177 aa) |
| | yjfM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (212 aa) |
| | cpdB | 2':3'-cyclic-nucleotide 2'-phosphodiesterase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the 5'-nucleotidase family. (647 aa) |
| | ytfM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (577 aa) |
| | ytfN | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (1259 aa) |
| | ytfQ | Putative sugar transporter subunit: periplasmic-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (318 aa) |
| | fimC | Chaperone, periplasmic; Function experimentally demonstrated in the studied species; factor. (241 aa) |
| | fimD | Outer membrane usher protein, type 1 fimbrial synthesis; Function experimentally demonstrated in the studied species; factor. (878 aa) |
| | mdoB | Phosphoglycerol transferase I; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (763 aa) |
| | osmY | Periplasmic protein; Function experimentally demonstrated in the studied species; cell process. (201 aa) |
| | slt | Lytic murein transglycosylase, soluble; Function experimentally demonstrated in the studied species; enzyme. (645 aa) |
