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| | ybiT | Putative transporter fused subunits of ABC superfamily: ATP-binding components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (530 aa) |
| | atpD | F1 sector of membrane-bound ATP synthase, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (460 aa) |
| | pstB | Phosphate transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the ABC transporter superfamily. (257 aa) |
| | trmE | GTPase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (454 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; factor. (467 aa) |
| | recF | Gap repair protein; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (357 aa) |
| | gmk | Guanylate kinase; Function experimentally demonstrated in the studied species; enzyme. (207 aa) |
| | selB | selenocysteinyl-tRNA-specific translation factor; Function experimentally demonstrated in the studied species; factor. (614 aa) |
| | xylG | Fused D-xylose transporter subunits of ABC superfamily: ATP-binding components; Function experimentally demonstrated in the studied species; transporter. (513 aa) |
| | dppD | Dipeptide transporter; Function experimentally demonstrated in the studied species; transporter; Belongs to the ABC transporter superfamily. (327 aa) |
| | dppF | Dipeptide transporter; Function experimentally demonstrated in the studied species; transporter. (334 aa) |
| | CAR00483.1 | Conserved hypothetical protein. (250 aa) |
| | rbbA | Fused ribosome-associated ATPase: ATP-binding protein; Function experimentally demonstrated in the studied species; enzyme. (911 aa) |
| | nikE | Nickel transporter subunit; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (268 aa) |
| | nikD | Nickel transporter subunit; Part of the ABC transporter complex NikABCDE involved in nickel import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Nickel importer (TC 3.A.1.5.3) family. (254 aa) |
| | ftsY | Fused Signal Recognition Particle (SRP) receptor: membrane binding protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components. (497 aa) |
| | ftsE | Transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter FtsEX involved in cellular division. (222 aa) |
| | livG | Leucine/isoleucine/valine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (255 aa) |
| | livF | Leucine/isoleucine/valine transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the ABC transporter superfamily. (237 aa) |
| | ugpC | Glycerol-3-phosphate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (356 aa) |
| | gntK | Gluconate kinase 2; Function experimentally demonstrated in the studied species; transporter. (175 aa) |
| | rtcR | Sigma 54-dependent transcriptional regulator of rtcBA expression; Function experimentally demonstrated in the studied species; regulator. (532 aa) |
| | aroK | Shikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | prkB | Phosphoribulokinase; Function of strongly homologous gene; enzyme. (289 aa) |
| | yheS | Fused putative transporter subunits of ABC superfamily: ATP-binding components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (637 aa) |
| | tufA | Protein chain elongation factor EF-Tu (duplicate of tufB); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (394 aa) |
| | aapP | Amino-acid transporter subunit; Function of strongly homologous gene; transporter. (252 aa) |
| | yhcM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (375 aa) |
| | lptB | Putative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (241 aa) |
| | yrbF | Toluene transporter subunit: ATP-binding component of ABC superfamily; Function of strongly homologous gene; transporter. (269 aa) |
| | obgE | GTPase involved in cell partioning and DNA repair; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (390 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (890 aa) |
| | deaD | ATP-dependent RNA helicase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the DEAD box helicase family. (629 aa) |
| | yghT | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (230 aa) |
| | yghS | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (237 aa) |
| | yghR | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (252 aa) |
| | yggR | Transporter; Function of homologous gene experimentally demonstrated in an other organism; transporter. (326 aa) |
| | yggC | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (237 aa) |
| | ecfA1_1 | Putative ATP-binding protein of ABC transport system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (236 aa) |
| | ecfA1_2 | Putative ATP-binding protein of ABC transport system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (227 aa) |
| | ruvB | ATP-dependent DNA helicase, component of RuvABC resolvasome; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa) |
| | araG | Fused L-arabinose transporter subunits of ABC superfamily: ATP-binding components; Function experimentally demonstrated in the studied species; transporter. (504 aa) |
| | yecC | Putative transporter subunit: ATP-binding component of ABC superfamily transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (250 aa) |
| | fliI | Flagellum-specific ATP synthase; Function experimentally demonstrated in the studied species; enzyme. (457 aa) |
| | cobU | Bifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase; Function experimentally demonstrated in the studied species; enzyme. (181 aa) |
| | wzc | Protein-tyrosine kinase; Function experimentally demonstrated in the studied species; enzyme. (720 aa) |
| | udk | Uridine/cytidine kinase; Function experimentally demonstrated in the studied species; enzyme. (213 aa) |
| | mrp | Antiporter inner membrane protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (369 aa) |
| | yehL | Putative ABC superfamily protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (362 aa) |
| | yehX | Putative transporter subunit: ATP-binding component of ABC superfamily transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (308 aa) |
| | mglA | Fused methyl-galactoside transporter subunits of ABC superfamily: ATP-binding components; Function experimentally demonstrated in the studied species; transporter. (506 aa) |
| | yeiR | Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (328 aa) |
| | yejF | Putative fused oligopeptide transporter subunits of ABC superfamily: ATP-binding components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily. (529 aa) |
| | yejH | Putative nucleic acid ATP-dependent helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (586 aa) |
| | ccmA | Heme exporter subunit; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. (207 aa) |
| | yojI | Multidrug transporter membrane component/ATP-binding component; Function experimentally demonstrated in the studied species; transporter. (547 aa) |
| | hisP | Histidine/lysine/arginine/ornithine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (257 aa) |
| | cysA | Sulfate/thiosulfate transporter subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa) |
| | eutP | Putative nucleoside triphosphate hydrolase domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the EutP/PduV family. (159 aa) |
| | hyfR | DNA-binding transcriptional activator, formate sensing; Function experimentally demonstrated in the studied species; regulator. (670 aa) |
| | hda | ATPase regulatory factor involved in DnaA inactivation; Mediates the interaction of DNA replication inititator protein DnaA with DNA polymerase subunit beta sliding clamp (dnaN). Stimulates hydrolysis of ATP-DnaA to ADP-DnaA, rendering DnaA inactive for reinititation, a process called regulatory inhibition of DnaA or RIDA; Belongs to the DnaA family. HdA subfamily. (248 aa) |
| | der | GTPase involved in ribosome synthesis and maintenance; Function experimentally demonstrated in the studied species; enzyme. (490 aa) |
| | yphE | Fused putative sugar transporter subunits of ABC superfamily: ATP-binding components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (503 aa) |
| | yfhA | Putative DNA-binding response regulator in two-component system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (444 aa) |
| | lepA | GTP-binding membrane protein; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (599 aa) |
| | srmB | ATP-dependent RNA helicase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the DEAD box helicase family. (444 aa) |
| | clpB | Protein disaggregation chaperone; Function experimentally demonstrated in the studied species; factor. (857 aa) |
| | ffh | Signal Recognition Particle (SRP) component with 4.5S RNA (ffs); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex [...] (453 aa) |
| | recN | Recombination and repair protein; May be involved in recombinational repair of damaged DNA. (553 aa) |
| | proV | Glycine betaine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (400 aa) |
| | recA | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (353 aa) |
| | norR | DNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (504 aa) |
| | hypB | GTP hydrolase involved in nickel liganding into hydrogenases; Function experimentally demonstrated in the studied species; enzyme. (290 aa) |
| | mutS | Methyl-directed mismatch repair protein; This protein is involved in the repair of mismatches in DNA. (853 aa) |
| | cysC | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (201 aa) |
| | cas3_2 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (899 aa) |
| | pyrG | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (545 aa) |
| | recD | Exonuclease V (RecBCD complex), alpha chain; Function experimentally demonstrated in the studied species; enzyme. (608 aa) |
| | recB | Exonuclease V (RecBCD complex), beta subunit; Function experimentally demonstrated in the studied species; enzyme. (1180 aa) |
| | recC | Exonuclease V (RecBCD complex), gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination [...] (1122 aa) |
| | ygeV | Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (592 aa) |
| | argK | Membrane ATPase/protein kinase; Function experimentally demonstrated in the studied species; transporter. (331 aa) |
| | hepA | RNA polymerase-associated helicase protein (ATPase and RNA polymerase recycling factor); Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair. Belongs to the SNF2/RAD54 helicase family. RapA subfamily. (968 aa) |
| | thiQ | Thiamin transporter subunit; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (232 aa) |
| | secA | Preprotein translocase subunit, ATPase; Function experimentally demonstrated in the studied species; transporter. (901 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa) |
| | hofB | Putative protein transport with triphosphate hydrolase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (461 aa) |
| | yadG | Putative transporter subunit: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (308 aa) |
| | hrpB | ATP-dependent (RNA) helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (809 aa) |
| | fhuC | Iron-hydroxamate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (265 aa) |
| | metN | DL-methionine transporter subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa) |
| | clpV1_4 | Putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the ClpA/ClpB family. (979 aa) |
| | rbsA_1 | Putative ATP-binding component of ABC sugar transport system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (499 aa) |
| | prpR | DNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (528 aa) |
| | tauB | Taurine transporter subunit; Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Taurine importer (TC 3.A.1.17.1) family. (255 aa) |
| | aroL | Shikimate kinase II; Function experimentally demonstrated in the studied species; enzyme. (174 aa) |
| | clpX | ATPase and specificity subunit of ClpX-ClpP ATP-dependent serine protease; Function experimentally demonstrated in the studied species; enzyme. (424 aa) |
| | mdlB | Putative fused ATPase and permease component of metabolite ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (593 aa) |
| | adk | Adenylate kinase; Function experimentally demonstrated in the studied species; enzyme. (214 aa) |
| | ybbL | Putative transporter subunit: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (225 aa) |
| | ybbA | Putative transporter subunit: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (228 aa) |
| | fepC | Iron-enterobactin transporter subunit; Function experimentally demonstrated in the studied species; transporter. (271 aa) |
| | holA | DNA polymerase III, delta subunit; Function experimentally demonstrated in the studied species; enzyme. (343 aa) |
| | gltL | Glutamate and aspartate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (241 aa) |
| | kdpD | Fused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein; Function experimentally demonstrated in the studied species; regulator. (894 aa) |
| | modF | Fused molybdate transporter subunits of ABC superfamily: ATP-binding components; Function experimentally demonstrated in the studied species; transporter. (490 aa) |
| | modC | Molybdate transporter subunit; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (352 aa) |
| | bioD | Dethiobiotin synthetase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (225 aa) |
| | uvrB | Excinulease of nucleotide excision repair, DNA damage recognition component; Function experimentally demonstrated in the studied species; cell process. (673 aa) |
| | ybhF | Putative transporter fused subunits of ABC superfamily: ATP-binding components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (578 aa) |
| | rhlE | RNA helicase; Function experimentally demonstrated in the studied species; enzyme. (454 aa) |
| | dinG | ATP-dependent DNA helicase; Function experimentally demonstrated in the studied species; enzyme. (716 aa) |
| | glnQ | Glutamine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (240 aa) |
| | yliA | Putative peptide transport fused subunits of ABC superfamily: ATP-binding components; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily. (612 aa) |
| | potG | Putrescine transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa) |
| | artP | Arginine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (242 aa) |
| | clpA | ATPase and specificity subunit of ClpA-ClpP ATP-dependent serine protease, chaperone activity; Function experimentally demonstrated in the studied species; enzyme; Belongs to the ClpA/ClpB family. (758 aa) |
| | cydC | Fused cysteine transporter subunits of ABC superfamily: membrane component; Function experimentally demonstrated in the studied species; transporter. (573 aa) |
| | rsgA | Ribosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (350 aa) |
| | yjdA | Conserved hypothetical protein; Important for the colocalization of sister nascent DNA strands after replication fork passage during DNA replication, and for positioning and subsequent partitioning of sister chromosomes. Does not have GTPase activity on its own (By similarity). (742 aa) |
| | phnC | Phosphonate/organophosphate ester transporter subunit; Function experimentally demonstrated in the studied species; transporter. (262 aa) |
| | phnK | Carbon-phosphorus lyase complex subunit; Function experimentally demonstrated in the studied species; enzyme. (252 aa) |
| | phnL | Carbon-phosphorus lyase complex subunit; Function experimentally demonstrated in the studied species; enzyme. (226 aa) |
| | phnN | Ribose 1,5-bisphosphokinase; Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP). (185 aa) |
| | uvrA | ATPase and DNA damage recognition protein of nucleotide excision repair excinuclease UvrABC; Function experimentally demonstrated in the studied species; enzyme. (940 aa) |
| | dnaB | Replicative DNA helicase; Function experimentally demonstrated in the studied species; enzyme. (471 aa) |
| | malK | Fused maltose transport subunit, ATP-binding component of ABC superfamily; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (371 aa) |
| | zraR | Two-component system response regulator; Function experimentally demonstrated in the studied species; regulator. (441 aa) |
| | coaA | Pantothenate kinase; Function experimentally demonstrated in the studied species; enzyme. (316 aa) |
| | priA | Primosome factor n' (replication factor Y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (732 aa) |
| | hslU | Molecular chaperone and ATPase component of HslUV protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (443 aa) |
| | bipA | GTP-binding protein; Function experimentally demonstrated in the studied species; factor. (607 aa) |
| | glnG | DNA-binding transcriptional regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa) |
| | yihA | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (198 aa) |
| | mobB | Molybdopterin-guanine dinucleotide biosynthesis protein B; Function experimentally demonstrated in the studied species; putative factor. (170 aa) |
| | uvrD | DNA-dependent ATPase I and helicase II; Function experimentally demonstrated in the studied species; enzyme. (720 aa) |
| | rho | Transcription termination factor; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (419 aa) |
| | rhlB | ATP-dependent RNA helicase; Function experimentally demonstrated in the studied species; enzyme. (421 aa) |
| | rep | DNA helicase and single-stranded DNA-dependent ATPase; Function experimentally demonstrated in the studied species; enzyme. (673 aa) |
| | yifB | Putative bifunctional enzyme and transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (516 aa) |
| | rbsA | Fused D-ribose transporter subunits of ABC superfamily: ATP-binding components; Function experimentally demonstrated in the studied species; transporter. (501 aa) |
| | ravA | Fused regulatory ATPase variant A; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family. (498 aa) |
| | atpA | F1 sector of membrane-bound ATP synthase, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (513 aa) |
| | cmk | Cytidylate kinase; Function experimentally demonstrated in the studied species; enzyme. (227 aa) |
| | msbA | Fused lipid transporter subunits of ABC superfamily: membrane component; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa) |
| | lpxK | Lipid A 4'kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (328 aa) |
| | ssuB | Alkanesulfonate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (255 aa) |
| | uup | Fused ATP-binding subunits of ABC superfamily protein involved in precise excision of transposons; Function experimentally demonstrated in the studied species; enzyme. (635 aa) |
| | sulA | SOS cell division inhibitor; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (169 aa) |
| | helD | DNA helicase IV; Function experimentally demonstrated in the studied species; enzyme. (684 aa) |
| | yjeE | ATPase with strong ADP affinity; Function experimentally demonstrated in the studied species; enzyme. (153 aa) |
| | miaA | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (316 aa) |
| | hflX | Putative GTPase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (426 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (432 aa) |
| | ytfR | Putative sugar transporter subunit: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (500 aa) |
| | yjgR | Putative ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (500 aa) |
| | yjiA | Putative GTPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (318 aa) |
| | dnaC | DNA biosynthesis protein; Function experimentally demonstrated in the studied species; cell process. (245 aa) |
| | prfC | Peptide chain release factor RF-3; Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily. (529 aa) |
| | radA | Repair protein radA homolog; Function of strongly homologous gene; cell process. (460 aa) |
| | nadR | Bifunctional DNA-binding transcriptional repressor and NMN adenylyltransferase; Function experimentally demonstrated in the studied species; regulator. (410 aa) |
| | yjjK | Fused putative transporter subunits of ABC superfamily: ATP-binding components; Function of strongly homologous gene; putative transporter. (555 aa) |
| | phoH | Putative phosphate starvation-inducible protein with ATPase activity; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (354 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (213 aa) |
| | holB | DNA polymerase III, delta prime subunit; Function experimentally demonstrated in the studied species; enzyme. (334 aa) |
| | mfd | Transcription-repair coupling factor; Function experimentally demonstrated in the studied species; factor. (1148 aa) |
| | lolD | Outer membrane-specific lipoprotein transporter subunit; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. (233 aa) |
| | potA | Polyamine transporter subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa) |
| | minD | Membrane ATPase of the MinC-MinD-MinE system; Function experimentally demonstrated in the studied species; factor. (270 aa) |
| | dhaR | DNA-binding transcriptional regulator, dihydroxyacetone metabolism; Function experimentally demonstrated in the studied species; regulator. (639 aa) |
| | ychF | Fragment of putative adhesin; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (363 aa) |
| | tdk | Thymidine kinase/deoxyuridine kinase; Function experimentally demonstrated in the studied species; enzyme. (205 aa) |
| | oppD | Oligopeptide transporter subunit; Function experimentally demonstrated in the studied species; transporter. (337 aa) |
| | oppF | Oligopeptide transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the ABC transporter superfamily. (334 aa) |
| | btuR | cob(I)alamin adenolsyltransferase/cobinamide ATP-dependent adenolsyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (196 aa) |
| | sapF | Antimicrobial peptide transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter. (268 aa) |
| | sapD | Antimicrobial peptide transporter subunit; Function of homologous gene experimentally demonstrated in an other organism; transporter; Belongs to the ABC transporter superfamily. (330 aa) |
| | pspF | DNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (325 aa) |
| | ycjV | Putative sugar transporter subunit: ATP-binding component of ABC superfamily transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (360 aa) |
| | tyrR | DNA-binding transcriptional dual regulator, tyrosine-binding; Function experimentally demonstrated in the studied species; regulator. (513 aa) |
| | dbpA | ATP-dependent RNA helicase, specific for 23S rRNA; Function experimentally demonstrated in the studied species; enzyme; Belongs to the DEAD box helicase family. (457 aa) |
| | hrpA | ATP-dependent helicase; Function experimentally demonstrated in the studied species; enzyme. (1281 aa) |
| | ydcT | Putative spermidine/putrescine transporter subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily. (337 aa) |
| | ddpF | D-ala-D-ala transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the ABC transporter superfamily. (308 aa) |
| | ddpD | D-ala-D-ala transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the ABC transporter superfamily. (328 aa) |
| | yddA | Putative multidrug transporter fused subunits of ABC superfamily transporter: permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (561 aa) |
| | ego | Fused AI2 transporter subunits of ABC superfamily: ATP-binding components; Function experimentally demonstrated in the studied species; transporter. (511 aa) |
| | A-2 | Terminase large subunit from bacteriophage origin; Function of homologous gene experimentally demonstrated in an other organism; extrachromosomal origin. (641 aa) |
| | ynfK | Putative synthase (similar to dethiobiotin synthetase); Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. (231 aa) |
| | lhr | Putative ATP-dependent helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1538 aa) |
| | sufC | Component of SufBCD complex, ATP-binding component of ABC superfamily; Function experimentally demonstrated in the studied species; transporter. (248 aa) |
| | btuD | Vitamin B12 transporter subunit : ATP-binding component of ABC superfamily; Function experimentally demonstrated in the studied species; transporter. (249 aa) |
| | ynjD | ATP-binding cassette domain-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (217 aa) |
| | yeaG | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (644 aa) |
| | yoaA | Putative ATP-dependent helicase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (636 aa) |
| | znuC | Zinc transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (251 aa) |
