STRINGSTRING
yfiE yfiE csiR csiR ygaV ygaV mprA mprA recX recX srlR srlR hosA hosA fucR fucR gcvA gcvA etrA etrA ygfI ygfI ygiP ygiP rpoD rpoD yqjI yqjI exuR exuR yhaJ yhaJ tdcA tdcA nanR nanR argR argR aaeR aaeR smf smf crp crp frlR frlR ompR ompR yhgG yhgG arsR arsR ygaV_1 ygaV_1 yhiF yhiF gadE gadE yhjC yhjC yiaU yiaU selB selB lldR lldR yidP yidP dgoR dgoR yieP yieP hdfR hdfR ilvY ilvY recQ recQ metR metR yihL yihL yihW yihW frvR frvR cpxR cpxR oxyR oxyR iclR iclR lexA lexA basR basR cadC cadC nsrR nsrR ulaR ulaR ytfH ytfH uxuR uxuR yjiE yjiE hpaR hpaR creB creB arcA arcA nhaR nhaR caiF caiF leuO leuO yafC yafC ykgK ykgK yahA yahA cynR cynR mhpR mhpR phoB phoB ybaO ybaO ybaZ ybaZ allR allR ybdO ybdO ybeF ybeF nagC nagC fur fur kdpE kdpE mngR mngR modE modE ybhD ybhD nohB nohB mntR mntR ycaN ycaN mukF mukF yceH yceH phoP phoP fadR fadR deoT deoT ycjZ ycjZ fnr fnr abgR abgR paaX paaX ydcR ydcR yncC yncC lsrR lsrR marR marR ydfH ydfH dgsA dgsA ynfL ynfL rstA rstA slyA slyA ydhB ydhB yeaT yeaT kdgR kdgR yebK yebK ruvB ruvB rcsA rcsA yedW yedW cbl cbl yeeY yeeY yegW yegW yeiE yeiE yeiI yeiI ada ada rcsB rcsB lrhA lrhA yfeR yfeR yfeT yfeT yffI yffI iscR iscR yphH yphH yfhH yfhH rpoE rpoE
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
yfiEPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (293 aa)
csiRDNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator. (220 aa)
ygaVPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (99 aa)
mprADNA-binding transcriptional repressor of microcin B17 synthesis and multidrug efflux; Function experimentally demonstrated in the studied species; regulator. (176 aa)
recXRegulatory protein for RecA; Modulates RecA activity; Belongs to the RecX family. (166 aa)
srlRDNA-bindng transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (257 aa)
hosATranscriptional regulator hosA; Involved in the temperature-dependent positive control of flagellum-driven swimming motility and cellular aggregation. Regulates fliC expression by directly interacting with fliC promoter (By similarity). (135 aa)
fucRDNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (243 aa)
gcvADNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (305 aa)
etrALuxR family transcriptional regulator; Homologs of previously reported genes of unknown function. (166 aa)
ygfIPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (298 aa)
ygiPPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (310 aa)
rpoDRNA polymerase, sigma 70 (sigma D) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (613 aa)
yqjIPutative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (207 aa)
exuRDNA-binding transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (258 aa)
yhaJPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (298 aa)
tdcADNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (312 aa)
nanRDNA-binding transcriptional dual regulator; Transcriptional repressor that controls expression of the genes required for the catabolism of sialic acids. (263 aa)
argRDNA-binding transcriptional dual regulator, L-arginine-binding; Regulates arginine biosynthesis genes. (156 aa)
aaeRDNA-binding transcriptional regulator, efflux system; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (309 aa)
smfConserved hypothetical protein; Homologs of previously reported genes of unknown function; 8432722. (374 aa)
crpDNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator. (210 aa)
frlRPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (243 aa)
ompRDNA-binding response regulator in two-component regulatory system with EnvZ; Function experimentally demonstrated in the studied species; regulator. (239 aa)
yhgGPutative DNA-binding transcriptional regulator; May function as a transcriptional regulator that controls feoABC expression. (78 aa)
arsRDNA-binding transcriptional repressor; Transcriptional repressor for the ars operon. ArsR is a trans-acting regulatory protein which controls its own expression. The repressive effect of ArsR is alleviated by oxyions of +III oxidation state of arsenic, antimony, and bismuth, as well as arsenate (As(V)). (117 aa)
ygaV_1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (119 aa)
yhiFPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (176 aa)
gadEDNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (175 aa)
yhjCPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (323 aa)
yiaUPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (324 aa)
selBselenocysteinyl-tRNA-specific translation factor; Function experimentally demonstrated in the studied species; factor. (614 aa)
lldRDNA-binding transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (258 aa)
yidPPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (238 aa)
dgoRPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (229 aa)
yiePPutative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (230 aa)
hdfRDNA-binding transcriptional regulator; Negatively regulates the transcription of the flagellar master operon flhDC by binding to the upstream region of the operon. (279 aa)
ilvYDNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (324 aa)
recQATP-dependent DNA helicase; Function experimentally demonstrated in the studied species; enzyme. (609 aa)
metRDNA-binding transcriptional activator, homocysteine-binding; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (317 aa)
yihLPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (236 aa)
yihWPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (261 aa)
frvRPutative regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (582 aa)
cpxRDNA-binding response regulator in two-component regulatory system with CpxA; Function experimentally demonstrated in the studied species; regulator. (232 aa)
oxyRDNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (305 aa)
iclRFragment of regulator of acetyl CoA synthetase (part 1); Gene remnant; regulator. (274 aa)
lexADNA-binding transcriptional repressor of SOS regulon; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (202 aa)
basRDNA-binding response regulator in two-component regulatory system with BasS; Function experimentally demonstrated in the studied species; regulator. (222 aa)
cadCDNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (512 aa)
nsrRDNA-binding transcriptional regulator; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity. (141 aa)
ulaRDNA-binding transcriptional dual regulator; Represses ulaG and the ulaABCDEF operon. (251 aa)
ytfHPutative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (126 aa)
uxuRDNA-binding transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (257 aa)
yjiEPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (303 aa)
hpaR4-hydroxyphenylacetate degradative operon repressor; Repressor for the homoprotocatechuate catabolic pathway hpc operon. (175 aa)
creBDNA-binding response regulator in two-component regulatory system with CreC; Function experimentally demonstrated in the studied species; regulator. (229 aa)
arcADNA-binding response regulator in two-component regulatory system with ArcB or CpxA; Function experimentally demonstrated in the studied species; regulator. (238 aa)
nhaRDNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (301 aa)
caiFTranscriptional activator; Function experimentally demonstrated in the studied species; regulator. (131 aa)
leuODNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (314 aa)
yafCPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (304 aa)
ykgKPutative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (196 aa)
yahACyclic di-GMP phosphodiesterase; Function experimentally demonstrated in the studied species; enzyme. (362 aa)
cynRDNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (299 aa)
mhpRDNA-binding transcriptional activator, 3HPP-binding; Function experimentally demonstrated in the studied species; regulator. (315 aa)
phoBDNA-binding response regulator in two-component regulatory system with PhoR (or CreC); Function experimentally demonstrated in the studied species; regulator. (229 aa)
ybaOPutative DNA-binding transcriptional regulator (Lrp-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (203 aa)
ybaZPutative methylated DNA-protein cysteine alkyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (129 aa)
allRDNA-binding transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (271 aa)
ybdOPutative DNA-binding transcriptional regulator, LysR-type; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (300 aa)
ybeFPutative DNA-binding transcriptional regulator, LysR-type; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (317 aa)
nagCDNA-binding transcriptional dual regulator, repressor of N-acetylglucosamine; Function experimentally demonstrated in the studied species; regulator. (406 aa)
furDNA-binding transcriptional dual regulator of siderophore biosynthesis and transport; Function experimentally demonstrated in the studied species; regulator; Belongs to the Fur family. (148 aa)
kdpEDNA-binding response regulator in two-component regulatory system with KdpD; Function experimentally demonstrated in the studied species; regulator. (225 aa)
mngRDNA-binding transcriptional dual regulator, fatty-acyl-binding; Function experimentally demonstrated in the studied species; regulator. (240 aa)
modEDNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator. (262 aa)
ybhDPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (338 aa)
nohBFragment of conserved hypothetical protein; Gene remnant; extrachromosomal origin. (181 aa)
mntRDNA-binding transcriptional regulator of mntH; Function experimentally demonstrated in the studied species; regulator. (155 aa)
ycaNPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (302 aa)
mukFInvolved in chromosome partioning, Ca2+ binding protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. (440 aa)
yceHConserved hypothetical protein; Homologs of previously reported genes of unknown function; 2828880; Belongs to the UPF0502 family. (215 aa)
phoPDNA-binding response regulator in two-component regulatory system with PhoQ; Function experimentally demonstrated in the studied species; regulator. (223 aa)
fadRDNA-binding transcriptional dual regulator of fatty acid metabolism; Multifunctional regulator of fatty acid metabolism. (239 aa)
deoTDNA-binding transcriptional repressor, DeoR family; Function experimentally demonstrated in the studied species; regulator. (249 aa)
ycjZFragment of putative hydrolase (part 1); Gene remnant; putative enzyme; Belongs to the LysR transcriptional regulatory family. (299 aa)
fnrDNA-binding transcriptional dual regulator, global regulator of anaerobic growth; Function experimentally demonstrated in the studied species; regulator. (250 aa)
abgRDNA-binding transcriptional regulator; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (302 aa)
paaXDNA-binding transcriptional repressor of phenylacetic acid degradation, aryl-CoA responsive; Function experimentally demonstrated in the studied species; regulator. (316 aa)
ydcRPutative DNA-binding transcriptional regulator fused with a domain with PLP-binding motif; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (468 aa)
yncCPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (221 aa)
lsrRDNA-binding transcriptional regulator; Function experimentally demonstrated in the studied species; regulator. (317 aa)
marRDNA-binding transcriptional repressor of multiple antibiotic resistance; Function experimentally demonstrated in the studied species; regulator. (144 aa)
ydfHPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (228 aa)
dgsADNA-binding transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (406 aa)
ynfLPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (297 aa)
rstADNA-binding response regulator in two-component regulatory system with RstB; Function experimentally demonstrated in the studied species; regulator. (242 aa)
slyADNA-binding transcriptional activator; Transcription regulator that can specifically activate or repress expression of target genes; Belongs to the SlyA family. (144 aa)
ydhBPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (310 aa)
yeaTPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (307 aa)
kdgRDNA-binding transcriptional repressor KdgR; Function experimentally demonstrated in the studied species; regulator. (263 aa)
yebKPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (289 aa)
ruvBATP-dependent DNA helicase, component of RuvABC resolvasome; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (336 aa)
rcsADNA-binding transcriptional activator, co-regulator with RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes (By similarity). Involved in regulation of K30 capsular polysaccharide synthesis. (207 aa)
yedWDNA-binding response regulator in two-component system with YedV; Function experimentally demonstrated in the studied species; regulator. (223 aa)
cblDNA-binding transcriptional activator of cysteine biosynthesis; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (316 aa)
yeeYPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (309 aa)
yegWPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (248 aa)
yeiEPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (293 aa)
yeiIPutative kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (362 aa)
adaFused DNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator. (354 aa)
rcsBDNA-binding response regulator in two-component regulatory system with RcsC and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner (By similarity). Involved in regulation of K30 capsular polysaccharide synthesis. (216 aa)
lrhADNA-binding transcriptional repressor of flagellar, motility and chemotaxis genes; Function experimentally demonstrated in the studied species; regulator; Belongs to the LysR transcriptional regulatory family. (312 aa)
yfeRPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the LysR transcriptional regulatory family. (308 aa)
yfeTPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (285 aa)
yffIPutative ethanolaminosome structural protein with putative role in ethanolamine utilization; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. (166 aa)
iscRDNA-binding transcriptional repressor; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins. (162 aa)
yphHPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (397 aa)
yfhHFused putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (282 aa)
rpoERNA polymerase, sigma 24 (sigma E) factor; Function experimentally demonstrated in the studied species; factor; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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