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frmB frmB frmA frmA gpmA gpmA serC serC torC torC torA torA torD torD pps pps pfkB pfkB torZ torZ torY torY CAQ98963.1 CAQ98963.1 fbaB fbaB frmC frmC ackA ackA pta pta glyA glyA eno eno serA serA fbaA fbaA yggF yggF mdh mdh gpmI gpmI fdoI fdoI fdoH fdoH fdoG fdoG pfkA pfkA glpX glpX ppc ppc acs acs fbp fbp serB serB ytjC ytjC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
frmBS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (277 aa)
frmAAlcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa)
gpmAFunction experimentally demonstrated in the studied species; enzyme. (250 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa)
torCTrimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the TorC/TorY family. (390 aa)
torATrimethylamine N-oxide (TMAO) reductase I, catalytic subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (848 aa)
torDChaperone involved in maturation of TorA subunit of trimethylamine N-oxide reductase system I; Function experimentally demonstrated in the studied species; factor. (199 aa)
ppsPhosphoenolpyruvate synthase; Function experimentally demonstrated in the studied species; enzyme. (792 aa)
pfkB6-phosphofructokinase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family. (309 aa)
torZTrimethylamine N-oxide reductase system III, catalytic subunit; Function experimentally demonstrated in the studied species; enzyme. (809 aa)
torYTMAO reductase III (TorYZ), cytochrome c-type subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the TorC/TorY family. (366 aa)
CAQ98963.1Hypothetical protein, putative Coenzyme F420-reducing hydrogenase, beta subunit; No homology to any previously reported sequences. (454 aa)
fbaBFructose-bisphosphate aldolase class I; Function experimentally demonstrated in the studied species; enzyme. (350 aa)
frmCS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (278 aa)
ackAAcetate kinase A and propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa)
ptaPhosphate acetyltransferase; Function experimentally demonstrated in the studied species; enzyme. (714 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa)
serAD-3-phosphoglycerate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa)
fbaAFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
yggFPutative hexoseP phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (321 aa)
mdhMalate dehydrogenase, NAD(P)-binding; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa)
gpmIPhosphoglycero mutase III, cofactor-independent; Function experimentally demonstrated in the studied species; enzyme. (514 aa)
fdoIFormate dehydrogenase-O, cytochrome b556 subunit; Function experimentally demonstrated in the studied species; carrier. (211 aa)
fdoHFormate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa)
fdoGFormate dehydrogenase-O, large subunit; Function experimentally demonstrated in the studied genus; enzyme. (1016 aa)
pfkA6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
glpXFructose 1,6-bisphosphatase II; Function experimentally demonstrated in the studied species; enzyme. (336 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (883 aa)
acsacetyl-CoA synthetase; Function experimentally demonstrated in the studied species; enzyme. (652 aa)
fbpFunction experimentally demonstrated in the studied species; enzyme. (332 aa)
serB3-phosphoserine phosphatase; Function experimentally demonstrated in the studied species; enzyme. (322 aa)
ytjCPhosphoglyceromutase 2, co-factor independent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa)
Your Current Organism:
Escherichia coli IAI1
NCBI taxonomy Id: 585034
Other names: E. coli IAI1, Escherichia coli str. IAI1, Escherichia coli strain IAI1
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