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| | talB | Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. (317 aa) |
| | aceE | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding; Function experimentally demonstrated in the studied species; enzyme. (887 aa) |
| | aceF | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; Function experimentally demonstrated in the studied species; enzyme. (630 aa) |
| | lpd | Lipoamide dehydrogenase, E3 component is part of three enzyme complexes; Function experimentally demonstrated in the studied species; enzyme. (474 aa) |
| | acnB | Bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase; Function experimentally demonstrated in the studied species; enzyme. (865 aa) |
| | accA | acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | yahI | Putative carbamate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the carbamate kinase family. (316 aa) |
| | frmB | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (277 aa) |
| | frmA | Alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa) |
| | ybcF | Putative carbamate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (297 aa) |
| | folD | 5,10-methylene-tetrahydrofolate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme. (288 aa) |
| | gltA | Citrate synthase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the citrate synthase family. (427 aa) |
| | sdhC | Succinate dehydrogenase, membrane subunit, binds cytochrome b556; Function experimentally demonstrated in the studied species; membrane component. (129 aa) |
| | sdhD | Succinate dehydrogenase, membrane subunit, binds cytochrome b556; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa) |
| | sdhA | Succinate dehydrogenase, flavoprotein subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa) |
| | sdhB | Succinate dehydrogenase, FeS subunit; Function experimentally demonstrated in the studied species; carrier. (238 aa) |
| | sucA | 2-oxoglutarate decarboxylase, thiamin-requiring; Function experimentally demonstrated in the studied species; enzyme. (933 aa) |
| | sucB | Dihydrolipoyltranssuccinase; Function experimentally demonstrated in the studied species; enzyme. (405 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | sucD | succinyl-CoA synthetase, NAD(P)-binding, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa) |
| | gpmA | Function experimentally demonstrated in the studied species; enzyme. (250 aa) |
| | pgl | 6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (331 aa) |
| | ybhJ | Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (753 aa) |
| | serC | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) |
| | icd | Isocitrate dehydrogenase, specific for NADP+; Function experimentally demonstrated in the studied species; extrachromosomal origin. (416 aa) |
| | prsA | Phosphoribosylpyrophosphate synthase; Function experimentally demonstrated in the studied species; enzyme. (315 aa) |
| | acnA | Aconitate hydratase 1; Function experimentally demonstrated in the studied species; enzyme. (891 aa) |
| | ydbK | Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1174 aa) |
| | paaH | 3-hydroxybutyryl-CoA dehydrogenase; Function experimentally demonstrated in the studied species; enzyme. (475 aa) |
| | gapC | Glyceraldehyde-3-phosphate dehydrogenase C; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (333 aa) |
| | sfcA | Malate dehydrogenase, (decarboxylating, NAD-requiring) (malic enzyme); Function experimentally demonstrated in the studied species; enzyme. (565 aa) |
| | CAQ98345.1 | Putative 3-hydroxyacyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (307 aa) |
| | CAQ98346.1 | Putative acetyl-CoA acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (401 aa) |
| | fumC | Fumarate hydratase (fumarase C),aerobic Class II; Function experimentally demonstrated in the studied species; enzyme. (467 aa) |
| | fumA | Fumarate hydratase (fumarase A), aerobic Class I; Function experimentally demonstrated in the studied species; enzyme. (548 aa) |
| | pykF | Pyruvate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pyruvate kinase family. (470 aa) |
| | pps | Phosphoenolpyruvate synthase; Function experimentally demonstrated in the studied species; enzyme. (792 aa) |
| | pfkB | 6-phosphofructokinase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family. (309 aa) |
| | katE | Hydroperoxidase HPII(III) (catalase); Serves to protect cells from the toxic effects of hydrogen peroxide. (753 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase A; Function experimentally demonstrated in the studied species; enzyme. (331 aa) |
| | sdaA | L-serine deaminase I; Function experimentally demonstrated in the studied species; enzyme. (454 aa) |
| | eda | 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase; Function experimentally demonstrated in the studied species; enzyme. (213 aa) |
| | edd | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | pykA | Pyruvate kinase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pyruvate kinase family. (480 aa) |
| | gnd | Gluconate-6-phosphate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | fbaB | Fructose-bisphosphate aldolase class I; Function experimentally demonstrated in the studied species; enzyme. (350 aa) |
| | frmC | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (278 aa) |
| | mqo | Malate dehydrogenase, FAD/NAD(P)-binding domain; Function experimentally demonstrated in the studied species; enzyme. (548 aa) |
| | ackA | Acetate kinase A and propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | pta | Phosphate acetyltransferase; Function experimentally demonstrated in the studied species; enzyme. (714 aa) |
| | accD | acetyl-CoA carboxylase, beta (carboxyltranferase) subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. Belongs to the AccD/PCCB family. (304 aa) |
| | yfcX | Fused enoyl-CoA hydratase and epimerase and isomerase; Function experimentally demonstrated in the studied species; enzyme. (714 aa) |
| | glk | Glucokinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the bacterial glucokinase family. (321 aa) |
| | cysK | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa) |
| | maeB | Putative fused malic enzyme oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (759 aa) |
| | talA | Transaldolase A; Function experimentally demonstrated in the studied species; enzyme. (316 aa) |
| | tktB | Transketolase 2, thiamin-binding; Function experimentally demonstrated in the studied species; enzyme; Belongs to the transketolase family. (667 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa) |
| | sdaB | L-serine deaminase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (455 aa) |
| | yqeF | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (393 aa) |
| | yqeA | Amino acid (carbamate) kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (310 aa) |
| | gcvP | Glycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (957 aa) |
| | gcvH | Glycine cleavage complex lipoylprotein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa) |
| | gcvT | Aminomethyltransferase, tetrahydrofolate-dependent, subunit (T protein) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine. (364 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) |
| | rpiA | Ribose 5-phosphate isomerase, constitutive; Function experimentally demonstrated in the studied species; enzyme. (219 aa) |
| | yliK | methylmalonyl-CoA mutase; Function experimentally demonstrated in the studied species; enzyme. (714 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | pgk | Phosphoglycerate kinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | yggF | Putative hexoseP phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (321 aa) |
| | tktA | Transketolase 1, thiamin-binding; Function experimentally demonstrated in the studied species; enzyme. (663 aa) |
| | glcB | Malate synthase G; Function experimentally demonstrated in the studied species; enzyme. (723 aa) |
| | tdcG | L-serine dehydratase 3; Function experimentally demonstrated in the studied species; enzyme; Belongs to the iron-sulfur dependent L-serine dehydratase family. (454 aa) |
| | tdcB | Catabolic threonine dehydratase, PLP-dependent; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (329 aa) |
| | mdh | Malate dehydrogenase, NAD(P)-binding; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa) |
| | accB | Acetyl CoA carboxylase, BCCP subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; Function experimentally demonstrated in the studied species; enzyme. (449 aa) |
| | prkB | Phosphoribulokinase; Function of strongly homologous gene; enzyme. (289 aa) |
| | rpe | D-ribulose-5-phosphate 3-epimerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | pck | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (540 aa) |
| | gntK | Gluconate kinase 2; Function experimentally demonstrated in the studied species; transporter. (175 aa) |
| | kdgK | Ketodeoxygluconokinase; Function experimentally demonstrated in the studied species; enzyme. (309 aa) |
| | cysE | Serine acetyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the transferase hexapeptide repeat family. (273 aa) |
| | gpmI | Phosphoglycero mutase III, cofactor-independent; Function experimentally demonstrated in the studied species; enzyme. (514 aa) |
| | ilvA | Threonine deaminase; Function experimentally demonstrated in the studied species; enzyme. (514 aa) |
| | fadB | Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (729 aa) |
| | yihU | Putative oxidoreductase with NAD(P)-binding Rossmann-fold domain; Reduces 3-sulfolactaldehyde (SLA) to 2,3-dihydroxypropane 1- sulfonate (DHPS); Belongs to the HIBADH-related family. 3-sulfolactaldehyde reductase subfamily. (298 aa) |
| | fdoI | Formate dehydrogenase-O, cytochrome b556 subunit; Function experimentally demonstrated in the studied species; carrier. (211 aa) |
| | fdoH | Formate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa) |
| | fdoG | Formate dehydrogenase-O, large subunit; Function experimentally demonstrated in the studied genus; enzyme. (1016 aa) |
| | pfkA | 6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | glpX | Fructose 1,6-bisphosphatase II; Function experimentally demonstrated in the studied species; enzyme. (336 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the methylenetetrahydrofolate reductase family. (296 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (883 aa) |
| | aceB | Malate synthase A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the malate synthase family. (533 aa) |
| | aceA | Isocitrate lyase; Function experimentally demonstrated in the studied species; enzyme. (434 aa) |
| | pgi | Glucosephosphate isomerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the GPI family. (549 aa) |
| | acs | acetyl-CoA synthetase; Function experimentally demonstrated in the studied species; enzyme. (652 aa) |
| | CAR01066.1 | Putative ribose-5-phosphate isomerase B (rpiB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (105 aa) |
| | fumB | Anaerobic class I fumarate hydratase (fumarase B); Function experimentally demonstrated in the studied species; enzyme. (548 aa) |
| | frdD | Fumarate reductase (anaerobic), membrane anchor subunit; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa) |
| | frdC | Fumarate reductase (anaerobic), membrane anchor subunit; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa) |
| | frdB | Fumarate reductase (anaerobic), Fe-S subunit; Function experimentally demonstrated in the studied species; carrier. (244 aa) |
| | frdA | Fumarate reductase (anaerobic) catalytic and NAD/flavoprotein subunit; Function experimentally demonstrated in the studied species; enzyme. (602 aa) |
| | fbp | Function experimentally demonstrated in the studied species; enzyme. (332 aa) |
| | serB | 3-phosphoserine phosphatase; Function experimentally demonstrated in the studied species; enzyme. (322 aa) |
| | ytjC | Phosphoglyceromutase 2, co-factor independent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
