(10 nodes) Ribosome network (Escherichia coli UMN026)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpsP	30S ribosomal subunit protein S16; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bS16 family. (82 aa)
	rpsO	30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. (89 aa)
	rpsI	30S ribosomal subunit protein S9; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS9 family. (130 aa)
	rplM	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (142 aa)
	yhdL	Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (72 aa)
	rplQ	50S ribosomal subunit protein L17; Function experimentally demonstrated in the studied species; structure. (127 aa)
	rpsK	30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (129 aa)
	rpsQ	30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (84 aa)
	rpmC	50S ribosomal subunit protein L29; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uL29 family. (63 aa)
	rplK	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (142 aa)

Your Current Organism:

Escherichia coli UMN026

NCBI taxonomy Id: 585056
Other names: E. coli UMN026

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rplK	rplM	ECUMN_4505	ECUMN_3705	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rplK	rplQ	ECUMN_4505	ECUMN_3768	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	50S ribosomal subunit protein L17; Function experimentally demonstrated in the studied species; structure.	0.999
rplK	rpmC	ECUMN_4505	ECUMN_3785	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	50S ribosomal subunit protein L29; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uL29 family.	0.999
rplK	rpsI	ECUMN_4505	ECUMN_3704	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	30S ribosomal subunit protein S9; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS9 family.	0.999
rplK	rpsK	ECUMN_4505	ECUMN_3771	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.999
rplK	rpsO	ECUMN_4505	ECUMN_3647	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.999
rplK	rpsP	ECUMN_4505	ECUMN_2934	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	30S ribosomal subunit protein S16; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bS16 family.	0.999
rplK	rpsQ	ECUMN_4505	ECUMN_3784	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.999
rplK	yhdL	ECUMN_4505	ECUMN_3765	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.999
rplM	rplK	ECUMN_3705	ECUMN_4505	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.999
rplM	rplQ	ECUMN_3705	ECUMN_3768	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	50S ribosomal subunit protein L17; Function experimentally demonstrated in the studied species; structure.	0.999
rplM	rpmC	ECUMN_3705	ECUMN_3785	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	50S ribosomal subunit protein L29; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uL29 family.	0.999
rplM	rpsI	ECUMN_3705	ECUMN_3704	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal subunit protein S9; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS9 family.	0.999
rplM	rpsK	ECUMN_3705	ECUMN_3771	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal subunit protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family.	0.999
rplM	rpsO	ECUMN_3705	ECUMN_3647	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal subunit protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.	0.999
rplM	rpsP	ECUMN_3705	ECUMN_2934	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal subunit protein S16; Function experimentally demonstrated in the studied species; structure; Belongs to the bacterial ribosomal protein bS16 family.	0.999
rplM	rpsQ	ECUMN_3705	ECUMN_3784	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	30S ribosomal subunit protein S17; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.	0.999
rplM	yhdL	ECUMN_3705	ECUMN_3765	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.999
rplQ	rplK	ECUMN_3768	ECUMN_4505	50S ribosomal subunit protein L17; Function experimentally demonstrated in the studied species; structure.	50S ribosomal subunit protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.999
rplQ	rplM	ECUMN_3768	ECUMN_3705	50S ribosomal subunit protein L17; Function experimentally demonstrated in the studied species; structure.	50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999