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| | sgrR | DNA-binding transcriptional regulator; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain. (559 aa) |
| | secM | Regulator of secA translation; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family. (170 aa) |
| | yacF | Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. (247 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (206 aa) |
| | yacL | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 7567469; Belongs to the UPF0231 family. (120 aa) |
| | yacC | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (172 aa) |
| | yaeH | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0325 family. (128 aa) |
| | yafD | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (266 aa) |
| | frsA | Hydrolase, binds to enzyme IIA(Glc); Displays esterase activity toward pNP-butyrate. (414 aa) |
| | crl | DNA-binding transcriptional regulator; Binds to the sigma-S subunit of RNA polymerase, activating expression of sigma-S-regulated genes. Stimulates RNA polymerase holoenzyme formation and may bind to several other sigma factors, such as sigma-70 and sigma-32; Belongs to the Crl family. (133 aa) |
| | phoE | Outer membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (351 aa) |
| | aroM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 3001025. (225 aa) |
| | yajG | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (192 aa) |
| | ybaE | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (566 aa) |
| | ybaY | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (190 aa) |
| | hha | Modulator of gene expression, with H-NS; Function experimentally demonstrated in the studied species; factor. (72 aa) |
| | ybaJ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 7984428, 14645275. (124 aa) |
| | nmpC | Putative outer membrane porin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin; Belongs to the Gram-negative porin family. (360 aa) |
| | uspG | Universal stress protein UP12; Function experimentally demonstrated in the studied species; factor. (142 aa) |
| | ybeL | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 12105207, 3320963, 7567469. (160 aa) |
| | ybfA | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (68 aa) |
| | ybgE | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (97 aa) |
| | ybiP | Putative enzyme, UPF0141 family, inner membrane; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (527 aa) |
| | bssR | Biofilm regulator; Function experimentally demonstrated in the studied species; regulator. (127 aa) |
| | ycbJ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (297 aa) |
| | mukF | Involved in chromosome partioning, Ca2+ binding protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. (440 aa) |
| | mukE | Protein involved in chromosome partitioning; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. (225 aa) |
| | mukB | Fused chromosome partitioning protein: putative nucleotide hydrolase; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1486 aa) |
| | ycbW | Conserved hypothetical protein; Contributes to the efficiency of the cell division process by stabilizing the polymeric form of the cell division protein FtsZ. Acts by promoting interactions between FtsZ protofilaments and suppressing the GTPase activity of FtsZ. (180 aa) |
| | ycbG | Conserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. (150 aa) |
| | yccR | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (209 aa) |
| | yccV | DNA-binding protein, hemimethylated; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. (105 aa) |
| | mdoC | Membrane protein required for modification of periplasmic glucan; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. (385 aa) |
| | solA | N-methyltryptophan oxidase, FAD-binding; Catalyzes the oxidative demethylation of N-methyl-L- tryptophan; Belongs to the MSOX/MTOX family. MTOX subfamily. (372 aa) |
| | bssS | Biofilm regulator; Function experimentally demonstrated in the studied species; regulator. (84 aa) |
| | yceB | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (186 aa) |
| | hinT | Purine nucleoside phosphoramidase; Function experimentally demonstrated in the studied species; enzyme. (119 aa) |
| | ycfL | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (125 aa) |
| | ycfP | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0227 family. (180 aa) |
| | ycfJ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 7984428. (179 aa) |
| | ycfQ | Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (210 aa) |
| | ycfR | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (85 aa) |
| | CAR12572.1 | Putative Lom-like outer membrane protein of phage origin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (199 aa) |
| | hns | Global nucleic acid-binding transcriptional dual regulator H-NS; Function experimentally demonstrated in the studied species; regulator; Belongs to the histone-like protein H-NS family. (137 aa) |
| | yciU | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0263 family. (109 aa) |
| | yciB | Putative intracellular septation protein involved in cell division; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (179 aa) |
| | yciC | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (247 aa) |
| | yciN | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 7567469, 9868784. (83 aa) |
| | yciS | Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa) |
| | yciM | Conserved hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family. (389 aa) |
| | uspE | Stress-induced protein; Function of strongly homologous gene; cell process. (316 aa) |
| | uspF | Stress-induced protein, ATP-binding protein; Function experimentally demonstrated in the studied species; factor. (144 aa) |
| | ompN | Outer membrane pore protein N, non-specific; Function experimentally demonstrated in the studied species; transporter. (377 aa) |
| | ydbH | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (879 aa) |
| | CAR12927.1 | Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family. (366 aa) |
| | ydeI | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (130 aa) |
| | CAR13016.1 | Putative Lom-like outer membrane protein of phage origin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (199 aa) |
| | ydgD | Putative exported metallopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S1B family. (273 aa) |
| | ydgH | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (314 aa) |
| | tus | Inhibitor of replication at Ter, DNA-binding protein; Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence; Belongs to the Tus family. (309 aa) |
| | ydgA | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (502 aa) |
| | ydgT | Post-transcriptional regulator; Function experimentally demonstrated in the studied species; regulator. (71 aa) |
| | ydgK | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (146 aa) |
| | ydhA | Putative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (109 aa) |
| | lpp | Murein lipoprotein; Function experimentally demonstrated in the studied species; lipoprotein. (78 aa) |
| | yniB | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (178 aa) |
| | osmE | DNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (112 aa) |
| | yoaH | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0181 family. (59 aa) |
| | yobD | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (152 aa) |
| | cutC | Copper homeostasis protein; Participates in the control of copper homeostasis. (248 aa) |
| | yecM | Putative metal-binding enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (188 aa) |
| | flhE | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 1482109, 89181349. (130 aa) |
| | yecG | Universal stress protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. (142 aa) |
| | yecF | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 7567469. (74 aa) |
| | CAR13447.1 | Porin OmpN; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family. (402 aa) |
| | CAR13472.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (42 aa) |
| | yeeX | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0265 family. (131 aa) |
| | yeeA | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (352 aa) |
| | cld | Regulator of length of O-antigen component of lipopolysaccharide chains; Function experimentally demonstrated in the studied species; regulator. (326 aa) |
| | asmA | Putative inner membrane protein involved in outer membrane protein assembly; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (617 aa) |
| | yejG | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (114 aa) |
| | yfbU | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0304 family. (164 aa) |
| | dedD | Conserved hypothetical protein; Non-essential cell division protein that could be required for efficient cell constriction. (220 aa) |
| | yfcZ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (94 aa) |
| | yfeY | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; 7764507. (191 aa) |
| | ypfG | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (347 aa) |
| | ypfN | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (66 aa) |
| | CAR14007.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (71 aa) |
| | sseB | Rhodanase-like enzyme, sulfur transfer from thiosulfate; Function experimentally demonstrated in the studied species; enzyme. (258 aa) |
| | stpA | DNA binding protein, nucleoid-associated; Function experimentally demonstrated in the studied species; regulator; Belongs to the histone-like protein H-NS family. (134 aa) |
| | ygaC | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (114 aa) |
| | iap | Aminopeptidase in alkaline phosphatase isozyme conversion; Function experimentally demonstrated in the studied species; enzyme. (345 aa) |
| | yqcE | Putative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (425 aa) |
| | ygdI | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (75 aa) |
| | zapA | Protein that localizes to the cytokinetic ring; Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division. (109 aa) |
| | yggN | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (239 aa) |
| | yggL | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (108 aa) |
| | yhcB | Putative cytochrome d ubiquinol oxidase subunit III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (132 aa) |
| | yhcN | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (87 aa) |
| | yhcO | Putative barnase inhibitor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (90 aa) |
| | aaeB | P-hydroxybenzoic acid efflux system component; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell. (655 aa) |
| | aaeA | P-hydroxybenzoic acid efflux system component; Forms an efflux pump with AaeB. (310 aa) |
| | aaeX | Membrane protein of efflux system; Function experimentally demonstrated in the studied species; transporter; Belongs to the AaeX family. (67 aa) |
| | yheO | Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (240 aa) |
| | yhfK | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (700 aa) |
| | tsgA | Putative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (393 aa) |
| | yhfL | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (55 aa) |
| | damX | Conserved hypothetical protein; Non-essential cell division protein. (428 aa) |
| | CAR15074.1 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (130 aa) |
| | yhhM | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (119 aa) |
| | yhhN | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (208 aa) |
| | yhiO | Putative universal stress (ethanol tolerance) protein B; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (111 aa) |
| | uspA | Universal stress global response regulator; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family. (144 aa) |
| | yhjG | Putative outer membrane biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (691 aa) |
| | yhjJ | Putative zinc-dependent peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (498 aa) |
| | yiaF | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (236 aa) |
| | yiaH | Conserved hypothetical protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units. (331 aa) |
| | mtlR | DNA-binding repressor; Function experimentally demonstrated in the studied species; regulator. (195 aa) |
| | yibL | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (120 aa) |
| | ttk | Division inhibitor; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions. (198 aa) |
| | yicH | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (569 aa) |
| | yidQ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (110 aa) |
| | yidR | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (404 aa) |
| | atpI | ATP synthase, membrane-bound accesory subunit; Function experimentally demonstrated in the studied species; enzyme. (126 aa) |
| | yieM | Putative von Willibrand factor containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (483 aa) |
| | ravA | Fused regulatory ATPase variant A; Functions as an ATPase. May play a role in metal insertion (metal-chelatase) or as a chaperone; Belongs to the RavA family. (498 aa) |
| | yihD | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (89 aa) |
| | yiiQ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (199 aa) |
| | yiiR | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (146 aa) |
| | yiiU | Conserved hypothetical protein; Non-essential, abundant cell division factor that is required for proper Z-ring formation. It is recruited early to the divisome by direct interaction with FtsZ, stimulating Z-ring assembly and thereby promoting cell division earlier in the cell cycle. Its recruitment to the Z-ring requires functional FtsA or ZipA. (81 aa) |
| | yijD | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (119 aa) |
| | cadA | Lysine decarboxylase 1; Function experimentally demonstrated in the studied species; enzyme. (715 aa) |
| | yjeI | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (117 aa) |
| | yjeP | Putative mechanosensitive channel; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (1107 aa) |
| | yjeT | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (65 aa) |
| | ytfB | Putative cell envelope opacity-associated protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. (212 aa) |
| | ytfJ | Putative transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (185 aa) |
| | ytfK | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (68 aa) |
| | mdoB | Phosphoglycerol transferase I; Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (763 aa) |
| | ytjB | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (214 aa) |
| | trpR | DNA-binding transcriptional repressor, tryptophan-binding; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (108 aa) |
