node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
basR | basS | ECUMN_4645 | ECUMN_4644 | DNA-binding response regulator in two-component regulatory system with BasS; Function experimentally demonstrated in the studied species; regulator. | Sensory histidine kinase in two-component regulatory system with BasR; Function experimentally demonstrated in the studied species; regulator. | 0.999 |
basR | phoQ | ECUMN_4645 | ECUMN_1373 | DNA-binding response regulator in two-component regulatory system with BasS; Function experimentally demonstrated in the studied species; regulator. | Sensory histidine kinase in two-compoent regulatory system with PhoP; Function experimentally demonstrated in the studied species; regulator. | 0.952 |
basR | pmrD | ECUMN_4645 | ECUMN_2602 | DNA-binding response regulator in two-component regulatory system with BasS; Function experimentally demonstrated in the studied species; regulator. | Polymyxin resistance protein B; Function experimentally demonstrated in the studied species; putative transporter. | 0.994 |
basR | yobG | ECUMN_4645 | ECUMN_2119 | DNA-binding response regulator in two-component regulatory system with BasS; Function experimentally demonstrated in the studied species; regulator. | Conserved hypothetical protein; PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. | 0.816 |
basS | basR | ECUMN_4644 | ECUMN_4645 | Sensory histidine kinase in two-component regulatory system with BasR; Function experimentally demonstrated in the studied species; regulator. | DNA-binding response regulator in two-component regulatory system with BasS; Function experimentally demonstrated in the studied species; regulator. | 0.999 |
basS | phoP | ECUMN_4644 | ECUMN_1374 | Sensory histidine kinase in two-component regulatory system with BasR; Function experimentally demonstrated in the studied species; regulator. | DNA-binding response regulator in two-component regulatory system with PhoQ; Function experimentally demonstrated in the studied species; regulator. | 0.964 |
basS | pmrD | ECUMN_4644 | ECUMN_2602 | Sensory histidine kinase in two-component regulatory system with BasR; Function experimentally demonstrated in the studied species; regulator. | Polymyxin resistance protein B; Function experimentally demonstrated in the studied species; putative transporter. | 0.812 |
basS | yobG | ECUMN_4644 | ECUMN_2119 | Sensory histidine kinase in two-component regulatory system with BasR; Function experimentally demonstrated in the studied species; regulator. | Conserved hypothetical protein; PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. | 0.819 |
phoP | basS | ECUMN_1374 | ECUMN_4644 | DNA-binding response regulator in two-component regulatory system with PhoQ; Function experimentally demonstrated in the studied species; regulator. | Sensory histidine kinase in two-component regulatory system with BasR; Function experimentally demonstrated in the studied species; regulator. | 0.964 |
phoP | phoQ | ECUMN_1374 | ECUMN_1373 | DNA-binding response regulator in two-component regulatory system with PhoQ; Function experimentally demonstrated in the studied species; regulator. | Sensory histidine kinase in two-compoent regulatory system with PhoP; Function experimentally demonstrated in the studied species; regulator. | 0.999 |
phoP | pmrD | ECUMN_1374 | ECUMN_2602 | DNA-binding response regulator in two-component regulatory system with PhoQ; Function experimentally demonstrated in the studied species; regulator. | Polymyxin resistance protein B; Function experimentally demonstrated in the studied species; putative transporter. | 0.810 |
phoP | yobG | ECUMN_1374 | ECUMN_2119 | DNA-binding response regulator in two-component regulatory system with PhoQ; Function experimentally demonstrated in the studied species; regulator. | Conserved hypothetical protein; PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. | 0.815 |
phoQ | basR | ECUMN_1373 | ECUMN_4645 | Sensory histidine kinase in two-compoent regulatory system with PhoP; Function experimentally demonstrated in the studied species; regulator. | DNA-binding response regulator in two-component regulatory system with BasS; Function experimentally demonstrated in the studied species; regulator. | 0.952 |
phoQ | phoP | ECUMN_1373 | ECUMN_1374 | Sensory histidine kinase in two-compoent regulatory system with PhoP; Function experimentally demonstrated in the studied species; regulator. | DNA-binding response regulator in two-component regulatory system with PhoQ; Function experimentally demonstrated in the studied species; regulator. | 0.999 |
phoQ | pmrD | ECUMN_1373 | ECUMN_2602 | Sensory histidine kinase in two-compoent regulatory system with PhoP; Function experimentally demonstrated in the studied species; regulator. | Polymyxin resistance protein B; Function experimentally demonstrated in the studied species; putative transporter. | 0.810 |
phoQ | yobG | ECUMN_1373 | ECUMN_2119 | Sensory histidine kinase in two-compoent regulatory system with PhoP; Function experimentally demonstrated in the studied species; regulator. | Conserved hypothetical protein; PhoP-regulated transcription is redox-sensitive, being activated when the periplasm becomes more reducing. MgrB acts between DsbA/DsbB and PhoP/PhoQ in this pathway. Represses PhoP/PhoQ signaling, possibly by binding to the periplasmic domain of PhoQ, altering its activity and that of downstream effector PhoP. | 0.900 |
pmrD | basR | ECUMN_2602 | ECUMN_4645 | Polymyxin resistance protein B; Function experimentally demonstrated in the studied species; putative transporter. | DNA-binding response regulator in two-component regulatory system with BasS; Function experimentally demonstrated in the studied species; regulator. | 0.994 |
pmrD | basS | ECUMN_2602 | ECUMN_4644 | Polymyxin resistance protein B; Function experimentally demonstrated in the studied species; putative transporter. | Sensory histidine kinase in two-component regulatory system with BasR; Function experimentally demonstrated in the studied species; regulator. | 0.812 |
pmrD | phoP | ECUMN_2602 | ECUMN_1374 | Polymyxin resistance protein B; Function experimentally demonstrated in the studied species; putative transporter. | DNA-binding response regulator in two-component regulatory system with PhoQ; Function experimentally demonstrated in the studied species; regulator. | 0.810 |
pmrD | phoQ | ECUMN_2602 | ECUMN_1373 | Polymyxin resistance protein B; Function experimentally demonstrated in the studied species; putative transporter. | Sensory histidine kinase in two-compoent regulatory system with PhoP; Function experimentally demonstrated in the studied species; regulator. | 0.810 |