STRINGSTRING
caiE caiE caiD caiD caiC caiC caiB caiB caiA caiA caiT caiT fixA fixA fixB fixB fixC fixC fixX fixX yaaU yaaU aes aes ydiO ydiO ydiQ ydiQ ydiR ydiR ydiS ydiS ydiT ydiT ydiD ydiD ygcN ygcN ygcO ygcO ygcP ygcP ygcQ ygcQ ygcR ygcR ygcS ygcS ygcU ygcU ygcW ygcW ygcE ygcE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
caiEPutative acyl transferase; Overproduction of CaiE stimulates the activity of CaiB and CaiD; Belongs to the transferase hexapeptide repeat family. (196 aa)
caiDCrotonobetainyl CoA hydratase; Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA. (274 aa)
caiCPutative crotonobetaine CoA ligase:carnitine CoA ligase; Catalyzes the transfer of CoA to carnitine, generating the initial carnitinyl-CoA needed for the CaiB reaction cycle. Also has activity toward crotonobetaine and gamma-butyrobetaine. (522 aa)
caiBCrotonobetainyl CoA:carnitine CoA transferase; Catalyzes the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA to L-carnitine to generate L-carnitinyl-CoA and gamma-butyrobetaine. Is also able to catalyze the reversible transfer of the CoA moiety from gamma-butyrobetainyl-CoA or L- carnitinyl-CoA to crotonobetaine to generate crotonobetainyl-CoA. Belongs to the CoA-transferase III family. CaiB subfamily. (405 aa)
caiACrotonobetaine reductase subunit II, FAD-binding; Catalyzes the reduction of crotonobetainyl-CoA to gamma- butyrobetainyl-CoA; Belongs to the acyl-CoA dehydrogenase family. (380 aa)
caiTL-carnitine/gamma-butyrobetaine antiporter; Catalyzes the exchange of L-carnitine for gamma-butyrobetaine and related betaines. (504 aa)
fixAPutative electron transfer flavoprotein subunit, ETFP adenine nucleotide-binding domain; Required for anaerobic carnitine reduction. May bring reductant to CaiA. (256 aa)
fixBProtein FixB; Required for anaerobic carnitine reduction. May bring reductant to CaiA. (313 aa)
fixCPutative oxidoreductase with FAD/NAD(P)-binding domain; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (428 aa)
fixXPutative 4Fe-4S ferredoxin; Could be a 3Fe-4S cluster-containing protein. (95 aa)
yaaUPutative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (443 aa)
aesAcetyl esterase; Displays esterase activity towards short chain fatty esters (acyl chain length of up to 8 carbons). Able to hydrolyze triacetylglycerol (triacetin) and tributyrylglycerol (tributyrin), but not trioleylglycerol (triolein) or cholesterol oleate. Negatively regulates MalT activity by antagonizing maltotriose binding. Inhibits MelA galactosidase activity. (319 aa)
ydiOPutative acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (383 aa)
ydiQPutative electron transfer flavoprotein subunit (etfB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (254 aa)
ydiRPutative electron transfer flavoprotein subunit, FAD-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (312 aa)
ydiSPutative oxidoreductase subunit with FAD/NAD(P)-binding domain; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (429 aa)
ydiTPutative 4Fe-4S ferredoxin-type oxidoreductase subunit; Could be a 3Fe-4S cluster-containing protein. (97 aa)
ydiDShort chain acyl-CoA synthetase, anaerobic; Function experimentally demonstrated in the studied species; enzyme. (566 aa)
ygcNPutative oxidoreductase with FAD/NAD(P)-binding domain; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (423 aa)
ygcOPutative 4Fe-4S cluster-containing protein; Could be a 3Fe-4S cluster-containing protein. (86 aa)
ygcPPutative anti-terminator regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (191 aa)
ygcQPutative flavoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (286 aa)
ygcRPutative flavoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (259 aa)
ygcSPutative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (445 aa)
ygcUPutative FAD containing dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (484 aa)
ygcWPutative deoxygluconate dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (261 aa)
ygcEPutative kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (492 aa)
Your Current Organism:
Escherichia coli UMN026
NCBI taxonomy Id: 585056
Other names: E. coli UMN026
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