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ybbB ybbB dmsA dmsA dmsB dmsB dmsC dmsC yccM yccM torS torS torT torT torR torR torC torC torA torA torD torD fdnG fdnG fdnH fdnH fdnI fdnI ydeP ydeP ynfE ynfE ynfF ynfF ynfG ynfG ynfH ynfH dmsD dmsD selD selD torZ torZ torY torY ccmH ccmH ccmG ccmG ccmF ccmF ccmE ccmE ccmD ccmD ccmC ccmC ccmB ccmB ccmA ccmA napC napC napB napB napH napH napG napG napA napA napD napD napF napF CAR13729.1 CAR13729.1 selB selB selA selA fdhE fdhE fdoI fdoI fdoH fdoH fdoG fdoG fdhD fdhD nrfA nrfA nrfB nrfB nrfC nrfC nrfD nrfD nrfE nrfE nrfF nrfF nrfG nrfG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ybbBtRNA 2-selenouridine synthase, selenophosphate-dependent; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain. (364 aa)
dmsADimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (814 aa)
dmsBDimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme. (205 aa)
dmsCDimethyl sulfoxide reductase, anaerobic, subunit C; Function experimentally demonstrated in the studied species; enzyme. (287 aa)
yccMPutative 4Fe-4S membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (357 aa)
torSHybrid sensory histidine kinase in two-component regulatory system with TorR; Function experimentally demonstrated in the studied species; regulator. (950 aa)
torTPeriplasmic sensory protein associated with the TorRS two-component regulatory system; Function experimentally demonstrated in the studied species; regulator. (342 aa)
torRDNA-binding response regulator in two-component regulatory system with TorS; Function experimentally demonstrated in the studied species; regulator. (230 aa)
torCTrimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the TorC/TorY family. (390 aa)
torATrimethylamine N-oxide (TMAO) reductase I, catalytic subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (848 aa)
torDChaperone involved in maturation of TorA subunit of trimethylamine N-oxide reductase system I; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily. (199 aa)
fdnGFormate dehydrogenase-N, alpha subunit, nitrate-inducible; Function experimentally demonstrated in the studied genus; enzyme. (1015 aa)
fdnHFormate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (294 aa)
fdnIFormate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible; Function experimentally demonstrated in the studied species; carrier. (217 aa)
ydePPutative oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (759 aa)
ynfEOxidoreductase subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (808 aa)
ynfFOxidoreductase subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (807 aa)
ynfGOxidoreductase, Fe-S subunit; Function experimentally demonstrated in the studied species; carrier. (205 aa)
ynfHOxidoreductase, membrane subunit; Function experimentally demonstrated in the studied species; membrane component. (284 aa)
dmsDTwin-argninine leader-binding protein for DmsA and TorA; Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding- maturation pathway for the substrate protein. (204 aa)
selDSelenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. (347 aa)
torZTrimethylamine N-oxide reductase system III, catalytic subunit; Function experimentally demonstrated in the studied species; enzyme. (809 aa)
torYTMAO reductase III (TorYZ), cytochrome c-type subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the TorC/TorY family. (366 aa)
ccmHHeme lyase, CcmH subunit; Possible subunit of a heme lyase. (350 aa)
ccmGPeriplasmic thioredoxin of cytochrome c-type biogenesis; Function experimentally demonstrated in the studied species; enzyme. (185 aa)
ccmFHeme lyase, CcmF subunit; Function experimentally demonstrated in the studied species; enzyme. (647 aa)
ccmEPeriplasmic heme chaperone; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (159 aa)
ccmDCytochrome c biogenesis protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (69 aa)
ccmCHeme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (245 aa)
ccmBHeme exporter subunit; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (220 aa)
ccmAHeme exporter subunit; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (207 aa)
napCNitrate reductase, cytochrome c-type,periplasmic; Function experimentally demonstrated in the studied species; carrier. (200 aa)
napBNitrate reductase, small, cytochrome C550 subunit, periplasmic; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (149 aa)
napHFerredoxin-type protein NapH; Function experimentally demonstrated in the studied species; carrier. (287 aa)
napGFerredoxin-type protein NapG; Function experimentally demonstrated in the studied species; carrier. (231 aa)
napANitrate reductase, periplasmic, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa)
napDAssembly protein for periplasmic nitrate reductase; Chaperone for NapA, the catalytic subunit of the periplasmic nitrate reductase. It binds directly and specifically to the twin- arginine signal peptide of NapA, preventing premature interaction with the Tat translocase and premature export. (87 aa)
napFFerredoxin-type protein, putative role in electron transfer to periplasmic nitrate reductase (NapA); Could be involved in the maturation of NapA, the catalytic subunit of the periplasmic nitrate reductase, before its export into the periplasm; Belongs to the NapF family. (164 aa)
CAR13729.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (57 aa)
selBselenocysteinyl-tRNA-specific translation factor; Function experimentally demonstrated in the studied species; factor. (614 aa)
selASelenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (463 aa)
fdhEFormate dehydrogenase formation protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (309 aa)
fdoIFormate dehydrogenase-O, cytochrome b556 subunit; Function experimentally demonstrated in the studied species; carrier. (211 aa)
fdoHFormate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa)
fdoGFormate dehydrogenase-O, large subunit; Function experimentally demonstrated in the studied genus; enzyme. (1016 aa)
fdhDFormate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (277 aa)
nrfANitrite reductase, formate-dependent, cytochrome; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (478 aa)
nrfBNitrite reductase, formate-dependent, penta-heme cytochrome c; Function experimentally demonstrated in the studied species; carrier. (188 aa)
nrfCFormate-dependent nitrite reductase, 4Fe4S subunit; Function experimentally demonstrated in the studied species; carrier. (223 aa)
nrfDFormate-dependent nitrite reductase, membrane subunit; Function experimentally demonstrated in the studied species; enzyme. (318 aa)
nrfEHeme lyase (NrfEFG) for insertion of heme into c552, subunit NrfE; Function experimentally demonstrated in the studied species; factor. (552 aa)
nrfFHeme lyase (NrfEFG) for insertion of heme into c552, subunit NrfF; Possible subunit of a heme lyase. (127 aa)
nrfGHeme lyase (NrfEFG) for insertion of heme into c552, subunit NrfG; Function experimentally demonstrated in the studied species; factor. (198 aa)
Your Current Organism:
Escherichia coli UMN026
NCBI taxonomy Id: 585056
Other names: E. coli UMN026
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