STRINGSTRING
hyaA hyaA hyaB hyaB hyaC hyaC hyaD hyaD hyaE hyaE hyaF hyaF hypF hypF hypA hypA hypB hypB hypC hypC hypD hypD hypE hypE hybG hybG hybF hybF hybE hybE hybD hybD hybC hybC hybB hybB hybA hybA hybO hybO CAR14639.1 CAR14639.1 yghW yghW
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hyaAHydrogenase 1, small subunit; Function experimentally demonstrated in the studied species; enzyme. (372 aa)
hyaBHydrogenase 1, large subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (597 aa)
hyaCHydrogenase 1, b-type cytochrome subunit; Function experimentally demonstrated in the studied species; carrier. (235 aa)
hyaDProtein involved in processing of HyaA and HyaB proteins; Function experimentally demonstrated in the studied species; factor. (195 aa)
hyaEProtein involved in processing of HyaA and HyaB proteins; Function experimentally demonstrated in the studied species; factor. (132 aa)
hyaFProtein involved in nickel incorporation into hydrogenase-1 proteins; Function experimentally demonstrated in the studied species; factor. (285 aa)
hypFCarbamoyl phosphate phosphatase and maturation protein for [NiFe] hydrogenases; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (770 aa)
hypAProtein involved in nickel insertion into hydrogenases 3; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (116 aa)
hypBGTP hydrolase involved in nickel liganding into hydrogenases; Function experimentally demonstrated in the studied species; enzyme. (290 aa)
hypCProtein required for maturation of hydrogenases 1 and 3; Function experimentally demonstrated in the studied species; factor. (90 aa)
hypDProtein required for maturation of hydrogenases; Function experimentally demonstrated in the studied species; factor; Belongs to the HypD family. (373 aa)
hypECarbamoyl phosphate phosphatase, hydrogenase 3 maturation protein; Function experimentally demonstrated in the studied species; enzyme. (322 aa)
hybGHydrogenase 2 accessory protein; Function experimentally demonstrated in the studied species; putative factor. (82 aa)
hybFProtein involved with the maturation of hydrogenases 1 and 2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)
hybEHydrogenase 2-specific chaperone; Function experimentally demonstrated in the studied species; factor. (162 aa)
hybDMaturation element for hydrogenase 2; Function of strongly homologous gene; factor. (164 aa)
hybCHydrogenase 2, large subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
hybBFunction of strongly homologous gene; carrier. (392 aa)
hybAHydrogenase 2 4Fe-4S ferredoxin-type component; Function experimentally demonstrated in the studied species; putative carrier. (328 aa)
hybOHydrogenase 2, small subunit; Function experimentally demonstrated in the studied species; enzyme. (372 aa)
CAR14639.1Conserved hypothetical protein; Doubtful CDS. (61 aa)
yghWConserved hypothetical protein; Homologs of previously reported genes of unknown function. (95 aa)
Your Current Organism:
Escherichia coli UMN026
NCBI taxonomy Id: 585056
Other names: E. coli UMN026
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