(8 nodes) Small ribosomal subunit network (Escherichia coli UMN026)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	rpsE	30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (167 aa)
	rpsL	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy. (124 aa)
	rpsG	30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (156 aa)
	rpsS	30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (92 aa)
	rpsB	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family. (241 aa)
	yhbH	Ribosome-associated, sigma 54 modulation protein; Function of strongly homologous gene; factor. (95 aa)
	rpsD	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (206 aa)
	yfiA	Cold shock protein associated with 30S ribosomal subunit; Function experimentally demonstrated in the studied species; factor. (113 aa)

Your Current Organism:

Escherichia coli UMN026

NCBI taxonomy Id: 585056
Other names: E. coli UMN026

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
rpsB	rpsD	ECUMN_0166	ECUMN_3770	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.996
rpsB	rpsE	ECUMN_0166	ECUMN_3776	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.999
rpsB	rpsG	ECUMN_0166	ECUMN_3801	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.997
rpsB	rpsL	ECUMN_0166	ECUMN_3802	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.	0.995
rpsB	rpsS	ECUMN_0166	ECUMN_3789	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family.	30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.996
rpsB	yfiA	ECUMN_0166	ECUMN_2923	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family.	Cold shock protein associated with 30S ribosomal subunit; Function experimentally demonstrated in the studied species; factor.	0.607
rpsB	yhbH	ECUMN_0166	ECUMN_3683	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family.	Ribosome-associated, sigma 54 modulation protein; Function of strongly homologous gene; factor.	0.865
rpsD	rpsB	ECUMN_3770	ECUMN_0166	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family.	0.996
rpsD	rpsE	ECUMN_3770	ECUMN_3776	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	0.999
rpsD	rpsG	ECUMN_3770	ECUMN_3801	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.999
rpsD	rpsL	ECUMN_3770	ECUMN_3802	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.	0.996
rpsD	rpsS	ECUMN_3770	ECUMN_3789	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.996
rpsD	yfiA	ECUMN_3770	ECUMN_2923	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	Cold shock protein associated with 30S ribosomal subunit; Function experimentally demonstrated in the studied species; factor.	0.629
rpsD	yhbH	ECUMN_3770	ECUMN_3683	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	Ribosome-associated, sigma 54 modulation protein; Function of strongly homologous gene; factor.	0.877
rpsE	rpsB	ECUMN_3776	ECUMN_0166	30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S2; Function experimentally demonstrated in the studied species; structure; Belongs to the universal ribosomal protein uS2 family.	0.999
rpsE	rpsD	ECUMN_3776	ECUMN_3770	30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.	0.999
rpsE	rpsG	ECUMN_3776	ECUMN_3801	30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.	0.998
rpsE	rpsL	ECUMN_3776	ECUMN_3802	30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S12; With S4 and S5 plays an important role in translational accuracy.	0.996
rpsE	rpsS	ECUMN_3776	ECUMN_3789	30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	30S ribosomal subunit protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.	0.999
rpsE	yfiA	ECUMN_3776	ECUMN_2923	30S ribosomal subunit protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.	Cold shock protein associated with 30S ribosomal subunit; Function experimentally demonstrated in the studied species; factor.	0.635