STRINGSTRING
hlpA hlpA iaaA iaaA hyaD hyaD rimJ rimJ rimL rimL ydeM ydeM sppA sppA lepB lepB hypA hypA hypB hypB hypC hypC hypD hypD hypE hypE pppA pppA hybG hybG hybF hybF hybE hybE hybD hybD CAR14944.1 CAR14944.1 slyD slyD gntY gntY yhhK yhhK yidF yidF aslB aslB fdhE fdhE rimI rimI lplA lplA lipA lipA lipB lipB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hlpAPeriplasmic chaperone; Function experimentally demonstrated in the studied species; factor; Belongs to the skp family. (161 aa)
iaaAIsoaspartyl dipeptidase with L-asparaginase activity; Function experimentally demonstrated in the studied species; enzyme. (321 aa)
hyaDProtein involved in processing of HyaA and HyaB proteins; Function experimentally demonstrated in the studied species; factor. (195 aa)
rimJribosomal-protein-S5-alanine N-acetyltransferase; Function experimentally demonstrated in the studied species; enzyme. (194 aa)
rimLribosomal-protein-L7/L12-serine acetyltransferase; Function experimentally demonstrated in the studied species; enzyme. (179 aa)
ydeMConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative regulator. (385 aa)
sppAProtease IV (signal peptide peptidase); Function experimentally demonstrated in the studied species; enzyme. (618 aa)
lepBLeader peptidase (signal peptidase I); Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S26 family. (324 aa)
hypAProtein involved in nickel insertion into hydrogenases 3; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (116 aa)
hypBGTP hydrolase involved in nickel liganding into hydrogenases; Function experimentally demonstrated in the studied species; enzyme. (290 aa)
hypCProtein required for maturation of hydrogenases 1 and 3; Function experimentally demonstrated in the studied species; factor. (90 aa)
hypDProtein required for maturation of hydrogenases; Function experimentally demonstrated in the studied species; factor; Belongs to the HypD family. (373 aa)
hypECarbamoyl phosphate phosphatase, hydrogenase 3 maturation protein; Function experimentally demonstrated in the studied species; enzyme. (322 aa)
pppABifunctional prepilin leader peptidase and methylase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. (269 aa)
hybGHydrogenase 2 accessory protein; Function experimentally demonstrated in the studied species; putative factor. (82 aa)
hybFProtein involved with the maturation of hydrogenases 1 and 2; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (113 aa)
hybEHydrogenase 2-specific chaperone; Function experimentally demonstrated in the studied species; factor. (162 aa)
hybDMaturation element for hydrogenase 2; Function of strongly homologous gene; factor. (164 aa)
CAR14944.1Putative bifunctional prepilin peptidase HopD: leader peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component; Belongs to the peptidase A24 family. (155 aa)
slyDFKBP-type peptidyl prolyl cis-trans isomerase (rotamase); Function experimentally demonstrated in the studied species; enzyme. (196 aa)
gntYPutative gluconate transport associated protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (191 aa)
yhhKConserved hypothetical protein; Controls both the activation and catalytic activity of PanD in a coenzyme A (CoA)-dependent fashion; Belongs to the PanZ/PanM family. (127 aa)
yidFPutative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (165 aa)
aslBRegulator of arylsulfatase activity; Function of homologous gene experimentally demonstrated in an other organism; putative regulator. (411 aa)
fdhEFormate dehydrogenase formation protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (309 aa)
rimIAcetylase for 30S ribosomal subunit protein S18; Acetylates the N-terminal alanine of ribosomal protein S18. (148 aa)
lplALipoate-protein ligase A; Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. (338 aa)
lipALipoate synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (321 aa)
lipBLipoyl-protein ligase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (213 aa)
Your Current Organism:
Escherichia coli UMN026
NCBI taxonomy Id: 585056
Other names: E. coli UMN026
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