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| | thrA | Fused aspartokinase I; Function experimentally demonstrated in the studied species; enzyme; In the C-terminal section; belongs to the homoserine dehydrogenase family. (820 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (310 aa) |
| | thrC | Threonine synthase; Function experimentally demonstrated in the studied species; enzyme. (428 aa) |
| | talB | Transaldolase B; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (317 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | araD | L-ribulose-5-phosphate 4-epimerase; Involved in the degradation of L-arabinose. Catalyzes the interconversion of L-ribulose 5-phosphate (LRu5P) and D-xylulose 5- phosphate (D-Xu5P) via a retroaldol/aldol mechanism (carbon-carbon bond cleavage analogous to a class II aldolase reaction). (231 aa) |
| | aceE | Pyruvate dehydrogenase, decarboxylase component E1, thiamin-binding; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (887 aa) |
| | aceF | Pyruvate dehydrogenase, dihydrolipoyltransacetylase component E2; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (630 aa) |
| | lpd | Lipoamide dehydrogenase, E3 component is part of three enzyme complexes; Function experimentally demonstrated in the studied species; enzyme. (474 aa) |
| | acnB | Bifunctional aconitate hydratase 2 and 2-methylisocitrate dehydratase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aconitase/IPM isomerase family. (865 aa) |
| | hemL | Glutamate-1-semialdehyde aminotransferase (aminomutase); Function experimentally demonstrated in the studied species; enzyme. (426 aa) |
| | dapD | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Function experimentally demonstrated in the studied species; enzyme. (274 aa) |
| | accA | acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (319 aa) |
| | ldcC | Lysine decarboxylase 2, constitutive; Function experimentally demonstrated in the studied species; enzyme. (713 aa) |
| | yagR | Putative oxidoreductase with molybdenum-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (732 aa) |
| | yagS | Putative oxidoreductase with FAD-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (318 aa) |
| | yahI | Putative carbamate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the carbamate kinase family. (316 aa) |
| | yahK | Putative oxidoreductase, Zn-dependent and NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (349 aa) |
| | mhpA | 3-(3-hydroxyphenyl)propionate hydroxylase; Catalyzes the insertion of one atom of molecular oxygen into position 2 of the phenyl ring of 3-(3-hydroxyphenyl)propionate (3-HPP) and hydroxycinnamic acid (3HCI). (554 aa) |
| | mhpB | 2,3-dihydroxyphenylpropionate 1,2-dioxygenase; Catalyzes the non-heme iron(II)-dependent oxidative cleavage of 2,3-dihydroxyphenylpropionic acid and 2,3-dihydroxicinnamic acid into 2-hydroxy-6-ketononadienedioate and 2-hydroxy-6- ketononatrienedioate, respectively; Belongs to the LigB/MhpB extradiol dioxygenase family. (314 aa) |
| | mhpC | 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; Catalyzes the cleavage of the C5-C6 bond of 2-hydroxy-6- oxononadienedioate and 2-hydroxy-6-oxononatrienedioate, a dienol ring fission product of the bacterial meta-cleavage pathway for degradation of phenylpropionic acid. (293 aa) |
| | mhpD | 2-keto-4-pentenoate hydratase; Catalyzes the conversion of 2-hydroxypentadienoic acid (enolic form of 2-oxopent-4-enoate) to 4-hydroxy-2-ketopentanoic acid. Belongs to the hydratase/decarboxylase family. MhpD subfamily. (269 aa) |
| | mhpF | acetaldehyde-CoA dehydrogenase II, NAD-binding; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (316 aa) |
| | mhpE | 4-hyroxy-2-oxovalerate/4-hydroxy-2-oxopentanoic acid aldolase, class I; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (337 aa) |
| | frmB | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (277 aa) |
| | frmA | Alcohol dehydrogenase class III/glutathione-dependent formaldehyde dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (369 aa) |
| | hemB | Porphobilinogen synthase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the ALAD family. (324 aa) |
| | allB | Allantoinase; Catalyzes the conversion of allantoin (5-ureidohydantoin) to allantoic acid by hydrolytic cleavage of the five-member hydantoin ring; Belongs to the metallo-dependent hydrolases superfamily. Allantoinase family. (453 aa) |
| | glxK | Glycerate kinase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycerate kinase type-1 family. (381 aa) |
| | ylbA | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (261 aa) |
| | allC | Allantoate amidohydrolase; Function experimentally demonstrated in the studied species; enzyme. (411 aa) |
| | allD | Ureidoglycolate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the LDH2/MDH2 oxidoreductase family. (349 aa) |
| | ybcF | Putative carbamate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the carbamate kinase family. (297 aa) |
| | folD | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa) |
| | nfnB | Dihydropteridine reductase, NAD(P)H-dependent, oxygen-insensitive; Function experimentally demonstrated in the studied species; enzyme. (217 aa) |
| | pgm | Phosphoglucomutase; Function experimentally demonstrated in the studied species; enzyme. (546 aa) |
| | gltA | Citrate synthase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the citrate synthase family. (427 aa) |
| | sdhC | Succinate dehydrogenase, membrane subunit, binds cytochrome b556; Function experimentally demonstrated in the studied species; membrane component. (129 aa) |
| | sdhD | Succinate dehydrogenase, membrane subunit, binds cytochrome b556; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (115 aa) |
| | sdhA | Succinate dehydrogenase, flavoprotein subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa) |
| | sdhB | Succinate dehydrogenase, FeS subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa) |
| | sucA | 2-oxoglutarate decarboxylase, thiamin-requiring; Function experimentally demonstrated in the studied species; enzyme. (933 aa) |
| | sucB | Dihydrolipoyltranssuccinase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (405 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa) |
| | sucD | succinyl-CoA synthetase, NAD(P)-binding, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (289 aa) |
| | CAR12022.1 | Fumarate hydratase class I, beta subunit, aerobic (Fumarase); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (550 aa) |
| | CAR12026.1 | Methylaspartate ammonia-lyase (Beta-methylaspartase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (413 aa) |
| | glmE | Methylaspartate mutase E chain (Glutamate mutase epsilon subunit); Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (481 aa) |
| | glmS-2 | Methylaspartate mutase S chain (Glutamate mutase sigma subunit); Catalyzes the carbon skeleton rearrangement of L-glutamate to L-threo-3-methylaspartate ((2S,3S)-3-methylaspartate). (170 aa) |
| | gpmA | Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (250 aa) |
| | galM | Galactose-1-epimerase (mutarotase); Converts alpha-aldose to the beta-anomer. (346 aa) |
| | pgl | 6-phosphogluconolactonase; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate. (331 aa) |
| | ybhJ | Putative enzyme; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (753 aa) |
| | ybiW | Putative glycyl radical cofactor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (810 aa) |
| | nfsA | Nitroreductase A, NADPH-dependent, FMN-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the flavin oxidoreductase frp family. (240 aa) |
| | CAR12259.1 | Putative transport protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (447 aa) |
| | CAR12260.1 | Putative phosphotransferase enzyme II, B component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (106 aa) |
| | ltaE | L-allo-threonine aldolase, PLP-dependent; Function experimentally demonstrated in the studied species; enzyme. (333 aa) |
| | pflB | Pyruvate formate lyase I; Function experimentally demonstrated in the studied species; enzyme. (760 aa) |
| | serC | 3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (362 aa) |
| | mgsA | Methylglyoxal synthase; Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate. (152 aa) |
| | yccX | Acylphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (163 aa) |
| | hyaA | Hydrogenase 1, small subunit; Function experimentally demonstrated in the studied species; enzyme. (372 aa) |
| | hyaB | Hydrogenase 1, large subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (597 aa) |
| | torC | Trimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the TorC/TorY family. (390 aa) |
| | torA | Trimethylamine N-oxide (TMAO) reductase I, catalytic subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (848 aa) |
| | torD | Chaperone involved in maturation of TorA subunit of trimethylamine N-oxide reductase system I; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily. (199 aa) |
| | agp | Glucose-1-phosphatase/inositol phosphatase; Function experimentally demonstrated in the studied species; enzyme. (413 aa) |
| | ycdW | 2-ketoacid reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. (312 aa) |
| | icd | Isocitrate dehydrogenase, specific for NADP+; Function experimentally demonstrated in the studied species; extrachromosomal origin. (416 aa) |
| | prsA | Phosphoribosylpyrophosphate synthase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (315 aa) |
| | hemA | Glutamyl tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (418 aa) |
| | narG | Nitrate reductase 1, alpha subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa) |
| | narH | Nitrate reductase 1, beta (Fe-S) subunit; Function experimentally demonstrated in the studied species; carrier. (512 aa) |
| | narI | Nitrate reductase 1, gamma (cytochrome b(NR)) subunit; Function experimentally demonstrated in the studied species; carrier. (225 aa) |
| | adhE | Fused acetaldehyde-CoA dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. (891 aa) |
| | acnA | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (891 aa) |
| | puuE | GABA aminotransferase, PLP-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (421 aa) |
| | ydbK | Putative 2-oxoacid-flavodoxin fused oxidoreductase:conserved protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1174 aa) |
| | ldhA | Fermentative D-lactate dehydrogenase, NAD-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (329 aa) |
| | ydbC | Putative aldo/keto reductase, NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (286 aa) |
| | aldA | Aldehyde dehydrogenase A, NAD-linked; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aldehyde dehydrogenase family. (479 aa) |
| | gapC | Glyceraldehyde-3-phosphate dehydrogenase C; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | ydcW | Medium chain aldehyde dehydrogenase; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (474 aa) |
| | narV | Nitrate reductase 2 (NRZ), gamma subunit; Function experimentally demonstrated in the studied species; enzyme. (226 aa) |
| | narY | Nitrate reductase 2 (NRZ), beta subunit; Function experimentally demonstrated in the studied species; carrier. (514 aa) |
| | narZ | Nitrate reductase 2 (NRZ), alpha subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1246 aa) |
| | adhP | Alcohol dehydrogenase, 1-propanol preferring; Function experimentally demonstrated in the studied species; carrier. (336 aa) |
| | gadB | Glutamate decarboxylase B, PLP-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the group II decarboxylase family. (466 aa) |
| | CAR12965.1 | Putative carboxymuconolactone decarboxylase precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (267 aa) |
| | CAR12972.1 | Putative Tas protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (315 aa) |
| | yneI | Putative aldehyde dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (462 aa) |
| | fumC | Fumarate hydratase (fumarase C),aerobic Class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa) |
| | fumA | Fumarate hydratase (fumarase A), aerobic Class I; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa) |
| | pdxH | Pyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (218 aa) |
| | nemA | N-ethylmaleimide reductase, FMN-linked; Function experimentally demonstrated in the studied species; enzyme. (365 aa) |
| | ydhU | Putative cytochrome b subunit of a reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (261 aa) |
| | ydhZ | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (69 aa) |
| | pykF | Pyruvate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pyruvate kinase family. (470 aa) |
| | ydiF | Short chain acyl-CoA transferase: fused alpha subunit; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family. (531 aa) |
| | pps | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa) |
| | pfkB | 6-phosphofructokinase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family. (309 aa) |
| | gdhA | Glutamate dehydrogenase, NADP-specific; Function experimentally demonstrated in the studied species; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (447 aa) |
| | gapA | Glyceraldehyde-3-phosphate dehydrogenase A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa) |
| | yeaD | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the glucose-6-phosphate 1-epimerase family. (294 aa) |
| | eda | 2-dehydro-3-deoxyphosphogluconate aldolase / (4S)-4-hydroxy-2-oxoglutarate aldolase; Function experimentally demonstrated in the studied species; enzyme. (213 aa) |
| | edd | 6-phosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa) |
| | zwf | Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | pykA | Pyruvate kinase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the pyruvate kinase family. (480 aa) |
| | torZ | Trimethylamine N-oxide reductase system III, catalytic subunit; Function experimentally demonstrated in the studied species; enzyme. (809 aa) |
| | torY | TMAO reductase III (TorYZ), cytochrome c-type subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the TorC/TorY family. (366 aa) |
| | hchA | Hsp31 molecular chaperone; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminocarbinols), [...] (283 aa) |
| | yedX | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (137 aa) |
| | gnd | Gluconate-6-phosphate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | fbaB | Fructose-bisphosphate aldolase class I; Function experimentally demonstrated in the studied species; enzyme. (350 aa) |
| | dld | D-lactate dehydrogenase, FAD-binding, NADH independent; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (571 aa) |
| | frmC | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (278 aa) |
| | fruA | Fused fructose-specific PTS enzymes: IIBcomponent; Function experimentally demonstrated in the studied species; transporter. (563 aa) |
| | napB | Nitrate reductase, small, cytochrome C550 subunit, periplasmic; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. (149 aa) |
| | napA | Nitrate reductase, periplasmic, large subunit; Catalytic subunit of the periplasmic nitrate reductase complex NapAB. Receives electrons from NapB and catalyzes the reduction of nitrate to nitrite. (828 aa) |
| | mqo | Malate dehydrogenase, FAD/NAD(P)-binding domain; Function experimentally demonstrated in the studied species; enzyme. (548 aa) |
| | atoD | acetyl-CoA:acetoacetyl-CoA transferase, alpha subunit; Function experimentally demonstrated in the studied species; carrier. (220 aa) |
| | atoA | acetyl-CoA:acetoacetyl-CoA transferase, beta subunit; Function experimentally demonstrated in the studied species; carrier. (216 aa) |
| | atoB | acetyl-CoA acetyltransferase; Function experimentally demonstrated in the studied species; carrier; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa) |
| | yfaU | Putative 2,4-dihydroxyhept-2-ene-1,7-dioic acid-like aldolase; Catalyzes the reversible retro-aldol cleavage of 2-keto-3- deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde. Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily. (267 aa) |
| | ackA | Acetate kinase A and propionate kinase 2; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (400 aa) |
| | pta | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (714 aa) |
| | ubiX | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (189 aa) |
| | accD | acetyl-CoA carboxylase, beta (carboxyltranferase) subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (304 aa) |
| | yfcX | Fused enoyl-CoA hydratase and epimerase and isomerase; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3- hydroxyacyl-CoA dehydrogenase activities; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (714 aa) |
| | yfcY | beta-ketoacyl-CoA thiolase, anaerobic, subunit; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (436 aa) |
| | glk | Glucokinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the bacterial glucokinase family. (321 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (471 aa) |
| | cysK | Cysteine synthase A, O-acetylserine sulfhydrolase A subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the cysteine synthase/cystathionine beta- synthase family. (323 aa) |
| | eutG | Putative alcohol dehydrogenase in ethanolamine utilization; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (395 aa) |
| | eutE | Putative aldehyde dehydrogenase, ethanolamine utilization protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (467 aa) |
| | maeB | Putative fused malic enzyme oxidoreductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (759 aa) |
| | talA | Transaldolase A; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (316 aa) |
| | tktB | Transketolase 2, thiamin-binding; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (667 aa) |
| | dapE | N-succinyl-diaminopimelate deacylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (375 aa) |
| | dapA | Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (292 aa) |
| | sseA | 3-mercaptopyruvate sulfurtransferase; Function experimentally demonstrated in the studied species; enzyme. (281 aa) |
| | hcaE | 3-phenylpropionate dioxygenase, large (alpha) subunit; Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively; Belongs to the bacterial ring-hydroxylating dioxygenase alpha subunit family. (453 aa) |
| | hcaF | 3-phenylpropionate dioxygenase, small (beta) subunit; Part of the multicomponent 3-phenylpropionate dioxygenase. Converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3- phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. (172 aa) |
| | hcaC | 3-phenylpropionate dioxygenase, putative ferredoxin subunit; Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. This protein seems to be a 2Fe-2S ferredoxin. (106 aa) |
| | hcaB | 2,3-dihydroxy-2,3-dihydrophenylpropionate dehydrogenase; Converts 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid-dihydrodiol (CI-dihydrodiol) into 3-(2,3- dihydroxylphenyl)propanoic acid (DHPP) and 2,3-dihydroxicinnamic acid (DHCI), respectively; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (270 aa) |
| | hcaD | Phenylpropionate dioxygenase, ferredoxin reductase subunit; Part of the multicomponent 3-phenylpropionate dioxygenase, that converts 3-phenylpropionic acid (PP) and cinnamic acid (CI) into 3-phenylpropionate-dihydrodiol (PP-dihydrodiol) and cinnamic acid- dihydrodiol (CI-dihydrodiol), respectively. (400 aa) |
| | glyA | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa) |
| | CAR14134.1 | Putative 3-hexulose-6-phosphate synthase from bacteriophage origin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (211 aa) |
| | CAR14135.1 | Putative 3-hexulose-6-phosphate isomerase (PHI) from bacteriophage origin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (188 aa) |
| | CAR14136.1 | Putative Glucose-6-phosphate isomerase from bacteriophage origin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (280 aa) |
| | ygaT | Conserved hypothetical protein; Acts as an alpha-ketoglutarate-dependent dioxygenase catalyzing hydroxylation of glutarate (GA) to L-2-hydroxyglutarate (L2HG). Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (325 aa) |
| | ygaF | Putative enzyme; Catalyzes the dehydrogenation of L-2-hydroxyglutarate (L2HG) to alpha-ketoglutarate and couples to the respiratory chain by feeding electrons from the reaction into the membrane quinone pool. Functions in a L-lysine degradation pathway that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. Reaction=(S)-2-hydroxyglutarate + a quinone = 2-oxoglutarate + a quinol; Xref=Rhea:RHEA:58664, ChEBI:CHEBI:16782, ChEBI:CHEBI:16810, ChEBI:CHEBI:24646, ChEBI:CHEBI:132124; PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:58665; Belongs to the L2HGDH family. (422 aa) |
| | gabD | Succinate-semialdehyde dehydrogenase I, NADP-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aldehyde dehydrogenase family. (482 aa) |
| | gabT | 4-aminobutyrate aminotransferase, PLP-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (426 aa) |
| | CAR14228.1 | Conserved putative non-oxidative reversible hydroxyarylic acid decarboxylase; Function experimentally demonstrated in the studied species; enzyme. (78 aa) |
| | CAR14229.1 | Conserved putative non-oxidative hydroxyarylic acid decarboxylase activity; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. (475 aa) |
| | CAR14230.1 | Conserved putative non-oxidative reversible hydroxyarylic acid decarboxylase; Involved in the non-oxidative decarboxylation and detoxification of phenolic derivatives. Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for phenolic acid decarboxylase. (197 aa) |
| | cysC | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (201 aa) |
| | cysN | Sulfate adenylyltransferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (475 aa) |
| | cysD | Sulfate adenylyltransferase, subunit 2; Function experimentally demonstrated in the studied species; enzyme. (302 aa) |
| | cysH | 3'-phosphoadenosine 5'-phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (244 aa) |
| | cysI | Sulfite reductase, beta subunit, NAD(P)-binding, heme-binding; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (570 aa) |
| | cysJ | Sulfite reductase, alpha subunit, flavoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. (599 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa) |
| | fucO | L-1,2-propanediol oxidoreductase; Function experimentally demonstrated in the studied species; enzyme. (383 aa) |
| | fucA | L-fuculose-1-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. (215 aa) |
| | fucI | L-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (591 aa) |
| | fucK | L-fuculokinase; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. (482 aa) |
| | lysA | Diaminopimelate decarboxylase, PLP-binding; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (420 aa) |
| | yqeF | Acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa) |
| | xdhA | Xanthine dehydrogenase, molybdenum binding subunit; Function experimentally demonstrated in the studied species; enzyme. (752 aa) |
| | xdhB | Xanthine dehydrogenase, FAD-binding subunit; Function experimentally demonstrated in the studied species; enzyme. (292 aa) |
| | xdhC | Xanthine dehydrogenase, Fe-S binding subunit; Function experimentally demonstrated in the studied species; carrier. (159 aa) |
| | yqeA | Amino acid (carbamate) kinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the carbamate kinase family. (310 aa) |
| | serA | D-3-phosphoglycerate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) |
| | rpiA | Ribose 5-phosphate isomerase, constitutive; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (219 aa) |
| | yliK | methylmalonyl-CoA mutase; Function experimentally demonstrated in the studied species; enzyme. (714 aa) |
| | fbaA | Fructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa) |
| | pgk | Phosphoglycerate kinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the phosphoglycerate kinase family. (387 aa) |
| | yggD | Putative DNA-binding transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (169 aa) |
| | yggF | Putative hexoseP phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (321 aa) |
| | tktA | Transketolase 1, thiamin-binding; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (663 aa) |
| | iucD | L-lysine 6-monooxygenase (Lysine N(6)-hydroxylase); Function experimentally demonstrated in the studied species; enzyme. (445 aa) |
| | iucC | Aerobactin siderophore biosynthesis protein; Function experimentally demonstrated in the studied species; enzyme. (580 aa) |
| | iucB | Aerobactin siderophore biosynthesis protein, N(6)-hydroxylysine acetylase; Function experimentally demonstrated in the studied species; enzyme. (315 aa) |
| | iucA | Aerobactin siderophore biosynthesis protein; Function experimentally demonstrated in the studied species; enzyme. (595 aa) |
| | glcB | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (723 aa) |
| | glcF | Glycolate oxidase iron-sulfur subunit; Function experimentally demonstrated in the studied species; carrier. (407 aa) |
| | glcE | Glycolate oxidase FAD binding subunit; Function experimentally demonstrated in the studied species; enzyme. (350 aa) |
| | glcD | Glycolate oxidase subunit, FAD-linked; Function experimentally demonstrated in the studied species; enzyme. (499 aa) |
| | hybC | Hydrogenase 2, large subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa) |
| | hybO | Hydrogenase 2, small subunit; Function experimentally demonstrated in the studied species; enzyme. (372 aa) |
| | CAR14641.1 | Putative enzyme; Homologs of previously reported genes of unknown function. (308 aa) |
| | ygjG | Putrescine:2-oxoglutaric acid aminotransferase, PLP-dependent; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (468 aa) |
| | tdcE | Pyruvate formate-lyase 4/2-ketobutyrate formate-lyase; Function experimentally demonstrated in the studied species; enzyme. (764 aa) |
| | garK | Glycerate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycerate kinase type-1 family. (408 aa) |
| | gltB | Glutamate synthase, large subunit; Function experimentally demonstrated in the studied species; enzyme. (1517 aa) |
| | gltD | Glutamate synthase, 4Fe-4S protein, small subunit; Function experimentally demonstrated in the studied species; carrier. (472 aa) |
| | mdh | Malate dehydrogenase, NAD(P)-binding; Catalyzes the reversible oxidation of malate to oxaloacetate. (312 aa) |
| | accB | Acetyl CoA carboxylase, BCCP subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (156 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (449 aa) |
| | prkB | Phosphoribulokinase; Function of strongly homologous gene; enzyme. (289 aa) |
| | argD | Bifunctional acetylornithine aminotransferase and succinyldiaminopimelate aminotransferase; Involved in both the arginine and lysine biosynthetic pathways; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (406 aa) |
| | nirB | Nitrite reductase, large subunit, NAD(P) H-binding; Function experimentally demonstrated in the studied species; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (847 aa) |
| | nirD | Nitrite reductase, NAD(P)H-binding, small subunit; Function experimentally demonstrated in the studied species; enzyme. (108 aa) |
| | cysG | Fused siroheme synthase 1, 3-dimethyluroporphyriongen III dehydrogenase and siroheme ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (457 aa) |
| | rpe | D-ribulose-5-phosphate 3-epimerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the ribulose-phosphate 3-epimerase family. (225 aa) |
| | pck | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (540 aa) |
| | glpE | Thiosulfate:cyanide sulfurtransferase (rhodanese); Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide. (108 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase, NAD(P)-binding; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (367 aa) |
| | gntK | Gluconate kinase 2; Function experimentally demonstrated in the studied species; transporter. (175 aa) |
| | gadA | Glutamate decarboxylase A, PLP-dependent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the group II decarboxylase family. (466 aa) |
| | kdgK | Ketodeoxygluconokinase; Function experimentally demonstrated in the studied species; enzyme. (309 aa) |
| | tiaE | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. (324 aa) |
| | sgbH | 3-keto-L-gulonate 6-phosphate decarboxylase; Function experimentally demonstrated in the studied species; enzyme. (220 aa) |
| | sgbU | Putative L-xylulose 5-phosphate 3-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (286 aa) |
| | sgbE | L-ribulose-5-phosphate 4-epimerase; Function experimentally demonstrated in the studied species; enzyme. (231 aa) |
| | aldB | Aldehyde dehydrogenase B; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aldehyde dehydrogenase family. (512 aa) |
| | yiaY | Fe-containing alcohol dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (383 aa) |
| | cysE | Serine acetyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the transferase hexapeptide repeat family. (273 aa) |
| | gpmI | Phosphoglycero mutase III, cofactor-independent; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (514 aa) |
| | dgoD | Galactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. (382 aa) |
| | hemX | Putative uroporphyrinogen III methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (403 aa) |
| | hemD | Uroporphyrinogen III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa) |
| | hemC | Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (313 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (274 aa) |
| | ysgA | Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (271 aa) |
| | fadA | 3-ketoacyl-CoA thiolase (thiolase I); Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (387 aa) |
| | fadB | Enoyl-CoA hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA isomerase/3-hydroxybutyryl-CoA epimerase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (729 aa) |
| | glnA | Glutamine synthetase; Function experimentally demonstrated in the studied species; enzyme. (469 aa) |
| | yihR | Putative aldose-1-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (303 aa) |
| | yihX | Putative hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (199 aa) |
| | fdoI | Formate dehydrogenase-O, cytochrome b556 subunit; Function experimentally demonstrated in the studied species; carrier. (211 aa) |
| | fdoH | Formate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa) |
| | fdoG | Formate dehydrogenase-O, large subunit; Function experimentally demonstrated in the studied genus; enzyme. (1016 aa) |
| | rhaD | Rhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily. (274 aa) |
| | rhaA | L-rhamnose isomerase; Function experimentally demonstrated in the studied species; enzyme. (419 aa) |
| | rhaB | Rhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. (489 aa) |
| | pfkA | 6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa) |
| | glpX | Fructose 1,6-bisphosphatase II; Function experimentally demonstrated in the studied species; enzyme. (336 aa) |
| | metL | Fused aspartokinase II; Function experimentally demonstrated in the studied species; enzyme; In the C-terminal section; belongs to the homoserine dehydrogenase family. (810 aa) |
| | metF | 5,10-methylenetetrahydrofolate reductase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the methylenetetrahydrofolate reductase family. (296 aa) |
| | pflD | Putative formate acetyltransferase 2 (pyruvate formate lyase II); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (765 aa) |
| | ppc | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (883 aa) |
| | aceB | Malate synthase A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the malate synthase family. (533 aa) |
| | aceA | Isocitrate lyase; Function experimentally demonstrated in the studied species; enzyme. (434 aa) |
| | lysC | Aspartokinase III; Function experimentally demonstrated in the studied species; enzyme; Belongs to the aspartokinase family. (449 aa) |
| | pgi | Glucosephosphate isomerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the GPI family. (549 aa) |
| | acs | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (652 aa) |
| | nrfA | Nitrite reductase, formate-dependent, cytochrome; Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process; Belongs to the cytochrome c-552 family. (478 aa) |
| | CAR15736.1 | Putative ribose-5-phosphate isomerase B (rpiB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (105 aa) |
| | fumB | Anaerobic class I fumarate hydratase (fumarase B); Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (548 aa) |
| | cadA | Lysine decarboxylase 1; Function experimentally demonstrated in the studied species; enzyme. (715 aa) |
| | frdD | Fumarate reductase (anaerobic), membrane anchor subunit; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa) |
| | frdC | Fumarate reductase (anaerobic), membrane anchor subunit; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa) |
| | frdB | Fumarate reductase (anaerobic), Fe-S subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa) |
| | frdA | Fumarate reductase (anaerobic) catalytic and NAD/flavoprotein subunit; Function experimentally demonstrated in the studied species; enzyme. (602 aa) |
| | ulaG | Putative L-ascorbate 6-phosphate lactonase; Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3- keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions; Belongs to the UlaG family. (354 aa) |
| | ulaA | L-ascorbate-specific enzyme IIC component of PTS; Function experimentally demonstrated in the studied species; transporter. (465 aa) |
| | ulaB | L-ascorbate-specific enzyme IIB component of PTS; Function experimentally demonstrated in the studied species; transporter. (101 aa) |
| | ulaC | L-ascorbate-specific enzyme IIA component of PTS; Function experimentally demonstrated in the studied species; transporter. (154 aa) |
| | ulaD | 3-keto-L-gulonate 6-phosphate decarboxylase; Catalyzes the decarboxylation of 3-keto-L-gulonate-6-P into L-xylulose-5-P. Is involved in the anaerobic L-ascorbate utilization. Belongs to the HPS/KGPDC family. KGPDC subfamily. (216 aa) |
| | ulaE | L-xylulose 5-phosphate 3-epimerase; Catalyzes the isomerization of L-xylulose-5-phosphate to L- ribulose-5-phosphate. Is involved in the anaerobic L-ascorbate utilization; Belongs to the L-ribulose-5-phosphate 3-epimerase family. (284 aa) |
| | ulaF | L-ribulose 5-phosphate 4-epimerase; Catalyzes the isomerization of L-ribulose 5-phosphate to D- xylulose 5-phosphate. Is involved in the anaerobic L-ascorbate utilization. (228 aa) |
| | cysQ | PAPS (adenosine 3'-phosphate 5'-phosphosulfate) 3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (246 aa) |
| | fbp | Function experimentally demonstrated in the studied species; enzyme. (332 aa) |
| | idnK | D-gluconate kinase, thermosensitive; Function experimentally demonstrated in the studied species; enzyme. (187 aa) |
| | yjgB | Putative alcohol dehydrogenase, Zn-dependent and NAD(P)-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (339 aa) |
| | mtnB | Methyl-thioribulose-1-phosphate dehydratase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. (213 aa) |
| | hpaC | 4-hydroxyphenylacetate 3-monooxygenase small component, Flavin:NADH reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (170 aa) |
| | hpaB | 4-hydroxyphenylacetate 3-monooxygenase large component; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (520 aa) |
| | hpaI | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Catalyzes the reversible retro-aldol cleavage of 4-hydroxy-2- ketoheptane-1,7-dioate (HKHD) to pyruvate and succinic semialdehyde. (268 aa) |
| | hpaH | 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (278 aa) |
| | hpaF | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (126 aa) |
| | hpaD | 3,4-dihydroxyphenylacetate 2,3-dioxygenase (Homoprotocatechuate 2,3-dioxygenase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (283 aa) |
| | hpaE | 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family. (488 aa) |
| | hpaG | 4-hydroxyphenylacetate degradation bifunctional isomerase/decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (431 aa) |
| | serB | 3-phosphoserine phosphatase; Function experimentally demonstrated in the studied species; enzyme. (322 aa) |
| | CAR16129.1 | Putative Aldo/keto reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (336 aa) |
| | ytjC | Phosphoglyceromutase 2, co-factor independent; Function experimentally demonstrated in the studied species; enzyme; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa) |
