STRINGSTRING
degP degP glnD glnD rcsF rcsF lafK lafK lfgM lfgM lafA lafA CAR11506.1 CAR11506.1 lafT lafT phoA phoA phoB phoB phoR phoR ybaS ybaS fimZ fimZ appY appY cusS cusS cusR cusR cusC cusC cusF cusF cusB cusB cusA cusA fepA fepA citT citT citG citG citX citX citF citF citE citE citD citD citC citC citA citA citB citB gltL gltL gltK gltK gltJ gltJ gltI gltI kdpE kdpE kdpD kdpD kdpC kdpC kdpB kdpB kdpA kdpA cydA cydA cydB cydB ybhC ybhC ompF ompF hyaA hyaA hyaB hyaB hyaC hyaC appC appC appB appB torS torS torR torR torC torC torA torA torD torD flgM flgM phoQ phoQ phoP phoP narL narL narX narX narG narG narH narH narJ narJ narI narI trg trg narV narV narW narW narY narY narZ narZ fdnG fdnG fdnH fdnH fdnI fdnI sfcA sfcA ddpX ddpX CAR12956.1 CAR12956.1 yneH yneH CAR13016.1 CAR13016.1 rstA rstA rstB rstB cheY cheY cheB cheB cheR cheR tap tap tar tar cheW cheW cheA cheA motA motA flhC flhC flhD flhD uvrY uvrY sdiA sdiA fliA fliA CAR13408.1 CAR13408.1 rcsA rcsA wzc wzc wzb wzb wza wza mdtA mdtA mdtB mdtB mdtC mdtC mdtD mdtD baeS baeS baeR baeR narP narP ompC ompC rcsD rcsD rcsB rcsB rcsC rcsC atoS atoS atoC atoC atoD atoD atoA atoA atoE atoE atoB atoB yfbE yfbE emrY emrY emrK emrK evgA evgA evgS evgS narQ narQ acrD acrD glnB glnB yfhA yfhA yfhK yfhK csrA csrA barA barA yqeF yqeF hybC hybC hybO hybO qseB qseB qseC qseC tolC tolC aer aer rpoN rpoN arcB arcB crp crp envZ envZ ompR ompR dctA dctA uhpT uhpT uhpC uhpC uhpB uhpB uhpA uhpA dnaA dnaA pstS pstS rffE rffE rffD rffD glnG glnG glnL glnL glnA glnA cpxA cpxA cpxR cpxR zraP zraP zraS zraS zraR zraR basS basS basR basR dcuB dcuB dcuR dcuR dcuS dcuS ampC ampC frdD frdD frdC frdC frdB frdB frdA frdA fecR fecR fecI fecI tsr tsr creB creB creC creC arcA arcA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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degPSerine endoprotease (protease Do), membrane-associated; Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S1C family. (474 aa)
glnDUridylyltransferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. (890 aa)
rcsFConserved hypothetical protein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. (134 aa)
lafKLateral flagellar RpoN-interacting regulatory protein; Function of strongly homologous gene; regulator. (326 aa)
lfgMLateral flagellar anti-sigma factor 28 protein (FlgM-like); Function of strongly homologous gene; regulator. (92 aa)
lafALateral flagellin (FliC-like); Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (326 aa)
CAR11506.1Putative RNA polymerase sigma factor for flagellar operon (FliA/lafS-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the sigma-70 factor family. (238 aa)
lafTChemotaxis protein lafT, Lateral flagellar motor protein A (MotA-like); Function of strongly homologous gene; structure. (287 aa)
phoABacterial alkaline phosphatase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the alkaline phosphatase family. (471 aa)
phoBDNA-binding response regulator in two-component regulatory system with PhoR (or CreC); Function experimentally demonstrated in the studied species; regulator. (229 aa)
phoRSensory histidine kinase in two-component regulatory system with PhoB; Function experimentally demonstrated in the studied species; regulator. (431 aa)
ybaSAmidase, possibly glutaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glutaminase family. (310 aa)
fimZDNA-binding transcriptional regulator, isolated component of a two-component regulator system; Function experimentally demonstrated in the studied species; regulator. (210 aa)
appYDNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (249 aa)
cusSSensory histidine kinase in two-component regulatory system with CusR, senses copper ions; Member of a two-component regulatory system. (486 aa)
cusRDNA-binding response regulator in two-component regulatory system with CusS; Function experimentally demonstrated in the studied species; regulator. (227 aa)
cusCCopper/silver efflux system, outer membrane component; Function experimentally demonstrated in the studied species; transporter. (462 aa)
cusFPeriplasmic copper-binding protein; Function of strongly homologous gene; factor. (110 aa)
cusBCopper/silver efflux system, membrane fusion protein; Function experimentally demonstrated in the studied species; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (407 aa)
cusACopper/silver efflux system, membrane component; Function experimentally demonstrated in the studied species; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1047 aa)
fepAIron-enterobactin outer membrane transporter; Function experimentally demonstrated in the studied species; transporter. (746 aa)
citTCitrate:succinate antiporter; Function experimentally demonstrated in the studied species; transporter. (487 aa)
citGtriphosphoribosyl-dephospho-CoA transferase; Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo- acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA; Belongs to the CitG/MdcB family. (292 aa)
citXApo-citrate lyase phosphoribosyl-dephospho-CoA transferase; Transfers 2-(5''-triphosphoribosyl)-3'-dephosphocoenzyme-A on a serine residue to the apo-acyl carrier protein (gamma chain) of the citrate lyase to yield holo-acyl carrier protein; Belongs to the CitX family. (183 aa)
citFCitrate lyase, citrate-ACP transferase (alpha) subunit; Function experimentally demonstrated in the studied species; enzyme. (510 aa)
citECitrate lyase, citryl-ACP lyase (beta) subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the HpcH/HpaI aldolase family. (302 aa)
citDCitrate lyase, acyl carrier (gamma) subunit; Covalent carrier of the coenzyme of citrate lyase. (98 aa)
citCCitrate lyase synthetase; Acetylation of prosthetic group (2-(5''-phosphoribosyl)-3'- dephosphocoenzyme-A) of the gamma subunit of citrate lyase. (352 aa)
citASensory histidine kinase in two-component regulatory system with citB; Function experimentally demonstrated in the studied species; regulator. (552 aa)
citBDNA-binding response regulator in two-component regulatory system with citA; Function experimentally demonstrated in the studied species; regulator. (226 aa)
gltLGlutamate and aspartate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (241 aa)
gltKGlutamate and aspartate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (224 aa)
gltJGlutamate and aspartate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (246 aa)
gltIGlutamate and aspartate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (302 aa)
kdpEDNA-binding response regulator in two-component regulatory system with KdpD; Function experimentally demonstrated in the studied species; regulator. (225 aa)
kdpDFused sensory histidine kinase in two-component regulatory system with KdpE: signal sensing protein; Function experimentally demonstrated in the studied species; regulator. (894 aa)
kdpCPotassium translocating ATPase, subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (190 aa)
kdpBPotassium translocating ATPase, subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa)
kdpAPotassium translocating ATPase, subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (557 aa)
cydACytochrome d terminal oxidase, subunit I; Function experimentally demonstrated in the studied species; carrier. (522 aa)
cydBCytochrome d terminal oxidase, subunit II; Function experimentally demonstrated in the studied species; carrier. (379 aa)
ybhCPectin methylesterase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (427 aa)
ompFOuter membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (362 aa)
hyaAHydrogenase 1, small subunit; Function experimentally demonstrated in the studied species; enzyme. (372 aa)
hyaBHydrogenase 1, large subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (597 aa)
hyaCHydrogenase 1, b-type cytochrome subunit; Function experimentally demonstrated in the studied species; carrier. (235 aa)
appCCytochrome bd-II oxidase, subunit I; Function experimentally demonstrated in the studied species; carrier. (514 aa)
appBCytochrome bd-II oxidase, subunit II; Function experimentally demonstrated in the studied species; carrier. (378 aa)
torSHybrid sensory histidine kinase in two-component regulatory system with TorR; Function experimentally demonstrated in the studied species; regulator. (950 aa)
torRDNA-binding response regulator in two-component regulatory system with TorS; Function experimentally demonstrated in the studied species; regulator. (230 aa)
torCTrimethylamine N-oxide (TMAO) reductase I, cytochrome c-type subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the TorC/TorY family. (390 aa)
torATrimethylamine N-oxide (TMAO) reductase I, catalytic subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (848 aa)
torDChaperone involved in maturation of TorA subunit of trimethylamine N-oxide reductase system I; Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor; Belongs to the TorD/DmsD family. TorD subfamily. (199 aa)
flgMAnti-sigma factor for FliA (sigma 28); Function experimentally demonstrated in the studied species; factor. (97 aa)
phoQSensory histidine kinase in two-compoent regulatory system with PhoP; Function experimentally demonstrated in the studied species; regulator. (486 aa)
phoPDNA-binding response regulator in two-component regulatory system with PhoQ; Function experimentally demonstrated in the studied species; regulator. (223 aa)
narLDNA-binding response regulator in two-component regulatory system with NarX (or NarQ); Function experimentally demonstrated in the studied species; regulator. (216 aa)
narXSensory histidine kinase in two-component regulatory system with NarL; Function experimentally demonstrated in the studied species; regulator. (598 aa)
narGNitrate reductase 1, alpha subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa)
narHNitrate reductase 1, beta (Fe-S) subunit; Function experimentally demonstrated in the studied species; carrier. (512 aa)
narJMolybdenum-cofactor-assembly chaperone subunit (delta subunit) of nitrate reductase 1; Function experimentally demonstrated in the studied species; factor. (236 aa)
narINitrate reductase 1, gamma (cytochrome b(NR)) subunit; Function experimentally demonstrated in the studied species; carrier. (225 aa)
trgMethyl-accepting chemotaxis protein III, ribose and galactose sensor receptor; Function experimentally demonstrated in the studied species; regulator. (546 aa)
narVNitrate reductase 2 (NRZ), gamma subunit; Function experimentally demonstrated in the studied species; enzyme. (226 aa)
narWNitrate reductase 2 (NRZ), delta subunit (assembly subunit); Function experimentally demonstrated in the studied species; factor. (231 aa)
narYNitrate reductase 2 (NRZ), beta subunit; Function experimentally demonstrated in the studied species; carrier. (514 aa)
narZNitrate reductase 2 (NRZ), alpha subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1246 aa)
fdnGFormate dehydrogenase-N, alpha subunit, nitrate-inducible; Function experimentally demonstrated in the studied genus; enzyme. (1015 aa)
fdnHFormate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (294 aa)
fdnIFormate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible; Function experimentally demonstrated in the studied species; carrier. (217 aa)
sfcAMalate dehydrogenase, (decarboxylating, NAD-requiring) (malic enzyme); Function experimentally demonstrated in the studied species; enzyme; Belongs to the malic enzymes family. (565 aa)
ddpXD-ala-D-ala dipeptidase, Zn-dependent; Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide. (193 aa)
CAR12956.1Conserved hypothetical protein; Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions; Belongs to the SafA family. (77 aa)
yneHPutative glutaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the glutaminase family. (308 aa)
CAR13016.1Putative Lom-like outer membrane protein of phage origin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (199 aa)
rstADNA-binding response regulator in two-component regulatory system with RstB; Function experimentally demonstrated in the studied species; regulator. (242 aa)
rstBSensory histidine kinase in two-component regulatory system with RstA; Function experimentally demonstrated in the studied species; regulator. (433 aa)
cheYChemotaxis regulator transmitting signal to flagellar motor component; Function experimentally demonstrated in the studied species; regulator. (129 aa)
cheBFused chemotaxis regulator; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (349 aa)
cheRChemotaxis regulator, protein-glutamate methyltransferase; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP. (286 aa)
tapMethyl-accepting protein IV; Function experimentally demonstrated in the studied species; regulator. (533 aa)
tarMethyl-accepting chemotaxis protein II; Function experimentally demonstrated in the studied species; regulator. (553 aa)
cheWPurine-binding chemotaxis protein; Function experimentally demonstrated in the studied species; regulator. (167 aa)
cheATwo-component system, chemotaxis family, sensor kinase CheA; Function experimentally demonstrated in the studied species; regulator. (654 aa)
motAProton conductor component of flagella motor; Function experimentally demonstrated in the studied species; cell process. (295 aa)
flhCDNA-binding transcriptional dual regulator with FlhD; Functions in complex with FlhD as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhC family. (192 aa)
flhDDNA-binding transcriptional dual regulator with FlhC; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family. (119 aa)
uvrYDNA-binding response regulator in two-component regulatory system with BarA; Function experimentally demonstrated in the studied species; regulator. (218 aa)
sdiADNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. (240 aa)
fliARNA polymerase, sigma 28 (sigma F) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (239 aa)
CAR13408.1FliC Flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. (554 aa)
rcsADNA-binding transcriptional activator, co-regulator with RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes. (207 aa)
wzcProtein-tyrosine kinase; Function experimentally demonstrated in the studied species; enzyme. (720 aa)
wzbProtein-tyrosine phosphatase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (147 aa)
wzaLipoprotein required for capsular polysaccharide translocation through the outer membrane; Function of strongly homologous gene; lipoprotein. (379 aa)
mdtAMultidrug efflux system, subunit A; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (415 aa)
mdtBMultidrug efflux system, subunit B; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtB subfamily. (1040 aa)
mdtCMultidrug efflux system, subunit C; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. MdtC subfamily. (1025 aa)
mdtDMultidrug efflux system protein; Function experimentally demonstrated in the studied species; transporter. (471 aa)
baeSSensory histidine kinase in two-component regulatory system with BaeR; Function experimentally demonstrated in the studied species; regulator. (467 aa)
baeRDNA-binding response regulator in two-component regulatory system with BaeS; Function experimentally demonstrated in the studied species; regulator. (240 aa)
narPDNA-binding response regulator in two-component regulatory system with NarQ or NarX; Function experimentally demonstrated in the studied species; regulator. (215 aa)
ompCOuter membrane porin protein C; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (367 aa)
rcsDPhosphotransfer intermediate protein in two-component regulatory system with RcsBC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (890 aa)
rcsBDNA-binding response regulator in two-component regulatory system with RcsC and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. (216 aa)
rcsCHybrid sensory kinase in two-component regulatory system with RcsB and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (933 aa)
atoSSensory histidine kinase in two-component regulatory system with AtoC; Function experimentally demonstrated in the studied species; regulator. (608 aa)
atoCFused response regulator of ato opeon, in two-component system with AtoS: response regulator; Function experimentally demonstrated in the studied species; regulator. (461 aa)
atoDacetyl-CoA:acetoacetyl-CoA transferase, alpha subunit; Function experimentally demonstrated in the studied species; carrier. (220 aa)
atoAacetyl-CoA:acetoacetyl-CoA transferase, beta subunit; Function experimentally demonstrated in the studied species; carrier. (216 aa)
atoEShort chain fatty acid transporter; Function experimentally demonstrated in the studied species; transporter. (440 aa)
atoBacetyl-CoA acetyltransferase; Function experimentally demonstrated in the studied species; carrier; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
yfbEUridine 5'-(beta-1-threo-pentapyranosyl-4-ulose diphosphate) aminotransferase, PLP-dependent; Catalyzes the conversion of UDP-4-keto-arabinose (UDP-Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the DegT/DnrJ/EryC1 family. ArnB subfamily. (385 aa)
emrYPutative multidrug efflux system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the major facilitator superfamily. (512 aa)
emrKEmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component; Function experimentally demonstrated in the studied species; transporter. (387 aa)
evgADNA-binding response regulator in two-component regulatory system with EvgS; Function experimentally demonstrated in the studied species; regulator. (204 aa)
evgSHybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. (1197 aa)
narQSensory histidine kinase in two-component regulatory system with NarP (NarL); Function experimentally demonstrated in the studied species; regulator. (566 aa)
acrDAminoglycoside/multidrug efflux system; Function experimentally demonstrated in the studied species; transporter. (1037 aa)
glnBRegulatory protein P-II for glutamine synthetase; Function experimentally demonstrated in the studied species; regulator; Belongs to the P(II) protein family. (112 aa)
yfhAPutative DNA-binding response regulator in two-component system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (444 aa)
yfhKPutative sensory kinase in two-component system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (475 aa)
csrAPleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small [...] (61 aa)
barAHybrid sensory histidine kinase, in two-component regulatory system with UvrY; Function experimentally demonstrated in the studied species; regulator. (918 aa)
yqeFAcetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
hybCHydrogenase 2, large subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. (567 aa)
hybOHydrogenase 2, small subunit; Function experimentally demonstrated in the studied species; enzyme. (372 aa)
qseBDNA-binding response regulator in two-component regulatory system with QseC; Function experimentally demonstrated in the studied species; regulator. (219 aa)
qseCSensory histidine kinase in two-component regulatory system with QseB; Function experimentally demonstrated in the studied species; regulator. (449 aa)
tolCTransport channel; Function experimentally demonstrated in the studied species; transporter. (493 aa)
aerFused signal transducer for aerotaxis sensory component; Function experimentally demonstrated in the studied species; regulator. (506 aa)
rpoNRNA polymerase, sigma 54 (sigma N) factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (477 aa)
arcBHybrid sensory histidine kinase in two-component regulatory system with ArcA; Function experimentally demonstrated in the studied species; regulator. (778 aa)
crpDNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator. (210 aa)
envZSensory histidine kinase in two-component regulatory system with OmpR; Function experimentally demonstrated in the studied species; regulator. (450 aa)
ompRDNA-binding response regulator in two-component regulatory system with EnvZ; Function experimentally demonstrated in the studied species; regulator. (239 aa)
dctAC4-dicarboxylic acid, orotate and citrate transporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (428 aa)
uhpTHexose phosphate transporter; Function experimentally demonstrated in the studied species; transporter. (463 aa)
uhpCMembrane protein regulates uhpT expression; Function experimentally demonstrated in the studied species; regulator. (439 aa)
uhpBSensory histidine kinase in two-component regulatory sytem with UhpA; Function experimentally demonstrated in the studied species; regulator. (500 aa)
uhpADNA-binding response regulator in two-component regulatory system wtih UhpB; Function experimentally demonstrated in the studied species; regulator. (196 aa)
dnaAChromosomal replication initiator protein DnaA, DNA-binding transcriptional dual regulator; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (467 aa)
pstSPhosphate transporter subunit; Part of the ABC transporter complex PstSACB involved in phosphate import; Belongs to the PstS family. (346 aa)
rffEUDP-N-acetyl glucosamine-2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa)
rffDUDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
glnGDNA-binding transcriptional regulator NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. (469 aa)
glnLSensory histidine kinase in two-component regulatory system with GlnG; Function experimentally demonstrated in the studied species; regulator. (349 aa)
glnAGlutamine synthetase; Function experimentally demonstrated in the studied species; enzyme. (469 aa)
cpxASensory histidine kinase in two-component regulatory system with CpxR; Function experimentally demonstrated in the studied species; regulator. (457 aa)
cpxRDNA-binding response regulator in two-component regulatory system with CpxA; Function experimentally demonstrated in the studied species; regulator. (232 aa)
zraPZn-binding periplasmic protein; Binds zinc. Could be an important component of the zinc- balancing mechanism; Belongs to the ZraP family. (139 aa)
zraSSensory histidine kinase in two-component regulatory system with ZraR; Function experimentally demonstrated in the studied species; regulator. (458 aa)
zraRTwo-component system, NtrC family, response regulator HydG; Function experimentally demonstrated in the studied species; regulator. (441 aa)
basSSensory histidine kinase in two-component regulatory system with BasR; Function experimentally demonstrated in the studied species; regulator. (363 aa)
basRDNA-binding response regulator in two-component regulatory system with BasS; Function experimentally demonstrated in the studied species; regulator. (222 aa)
dcuBC4-dicarboxylate antiporter; Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane; Belongs to the DcuA/DcuB transporter (TC 2.A.13.1) family. (446 aa)
dcuRDNA-binding response regulator in two-component regulatory system with DcuS; Function experimentally demonstrated in the studied species; regulator. (239 aa)
dcuSTwo-component system, CitB family, sensor histidine kinase DcuS; Function experimentally demonstrated in the studied species; regulator. (543 aa)
ampCbeta-lactamase/D-alanine carboxypeptidase; Function experimentally demonstrated in the studied species; enzyme. (377 aa)
frdDFumarate reductase (anaerobic), membrane anchor subunit; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa)
frdCFumarate reductase (anaerobic), membrane anchor subunit; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (131 aa)
frdBFumarate reductase (anaerobic), Fe-S subunit; Function experimentally demonstrated in the studied species; carrier; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (244 aa)
frdAFumarate reductase (anaerobic) catalytic and NAD/flavoprotein subunit; Function experimentally demonstrated in the studied species; enzyme. (602 aa)
fecRTransmembrane signal transducer for ferric citrate transport; Function experimentally demonstrated in the studied species; regulator. (317 aa)
fecIRNA polymerase, sigma 19 factor; Function experimentally demonstrated in the studied species; regulator; Belongs to the sigma-70 factor family. ECF subfamily. (173 aa)
tsrMethyl-accepting chemotaxis protein I, serine sensor receptor; Function experimentally demonstrated in the studied species; regulator. (554 aa)
creBDNA-binding response regulator in two-component regulatory system with CreC; Function experimentally demonstrated in the studied species; regulator. (229 aa)
creCTwo-component system, OmpR family, sensor histidine kinase CreC; Function experimentally demonstrated in the studied species; regulator. (474 aa)
arcADNA-binding response regulator in two-component regulatory system with ArcB or CpxA; Function experimentally demonstrated in the studied species; regulator. (238 aa)
Your Current Organism:
Escherichia coli UMN026
NCBI taxonomy Id: 585056
Other names: E. coli UMN026
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