node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CAR17487.1 | garK | ECIAI39_1353 | ECIAI39_3623 | Putative 2-hydroxyacid dehydrogenase/reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Glycerate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycerate kinase type-1 family. | 0.900 |
CAR17487.1 | tiaE | ECIAI39_1353 | ECIAI39_4061 | Putative 2-hydroxyacid dehydrogenase/reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.924 |
CAR17487.1 | ycdW | ECIAI39_1353 | ECIAI39_2130 | Putative 2-hydroxyacid dehydrogenase/reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 2-ketoacid reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.918 |
garK | CAR17487.1 | ECIAI39_3623 | ECIAI39_1353 | Glycerate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycerate kinase type-1 family. | Putative 2-hydroxyacid dehydrogenase/reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.900 |
garK | tiaE | ECIAI39_3623 | ECIAI39_4061 | Glycerate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycerate kinase type-1 family. | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.919 |
garK | ycdW | ECIAI39_3623 | ECIAI39_2130 | Glycerate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycerate kinase type-1 family. | 2-ketoacid reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.900 |
gph | tiaE | ECIAI39_3863 | ECIAI39_4061 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.920 |
gph | ycdW | ECIAI39_3863 | ECIAI39_2130 | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | 2-ketoacid reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.910 |
tiaE | CAR17487.1 | ECIAI39_4061 | ECIAI39_1353 | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | Putative 2-hydroxyacid dehydrogenase/reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.924 |
tiaE | garK | ECIAI39_4061 | ECIAI39_3623 | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | Glycerate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycerate kinase type-1 family. | 0.919 |
tiaE | gph | ECIAI39_4061 | ECIAI39_3863 | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | 0.920 |
tiaE | ycdW | ECIAI39_4061 | ECIAI39_2130 | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 2-ketoacid reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 0.922 |
ycdW | CAR17487.1 | ECIAI39_2130 | ECIAI39_1353 | 2-ketoacid reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | Putative 2-hydroxyacid dehydrogenase/reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.918 |
ycdW | garK | ECIAI39_2130 | ECIAI39_3623 | 2-ketoacid reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | Glycerate kinase I; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycerate kinase type-1 family. | 0.900 |
ycdW | gph | ECIAI39_2130 | ECIAI39_3863 | 2-ketoacid reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family. | 0.910 |
ycdW | tiaE | ECIAI39_2130 | ECIAI39_4061 | 2-ketoacid reductase; Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. | 2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. GhrB subfamily. | 0.922 |