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mogA mogA thiQ thiQ thiP thiP tbpA tbpA CAR16215.1 CAR16215.1 thiL thiL modF modF modE modE ybhT ybhT modA modA modB modB modC modC ybhA ybhA moaA moaA moaB moaB moaC moaC moaD moaD moaE moaE moeB moeB moeA moeA thiM thiM thiD thiD ycfN ycfN ycbX ycbX yiiM yiiM mobA mobA mobB mobB thiH thiH thiG thiG thiS thiS thiF thiF thiE thiE thiC thiC rsgA rsgA
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mogAMolybdochelatase MogA, involved in Moco biosynthesis; Function experimentally demonstrated in the studied species; factor. (195 aa)
thiQThiamin transporter subunit; Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Thiamine importer (TC 3.A.1.19.1) family. (232 aa)
thiPFused thiamin transporter subunits of ABC superfamily: membrane components; Function experimentally demonstrated in the studied species; transporter. (536 aa)
tbpAThiamin transporter subunit; Function experimentally demonstrated in the studied species; transporter. (327 aa)
CAR16215.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (189 aa)
thiLThiamin-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (325 aa)
modFFused molybdate transporter subunits of ABC superfamily: ATP-binding components; Function experimentally demonstrated in the studied species; transporter. (490 aa)
modEDNA-binding transcriptional dual regulator; Function experimentally demonstrated in the studied species; regulator. (262 aa)
ybhTConserved hypothetical protein; AcrA-AcrB-AcrZ-TolC is a drug efflux protein complex with a broad substrate specificity. This protein binds to AcrB and is required for efflux of some but not all substrates, suggesting it may influence the specificity of drug export. (49 aa)
modAMolybdate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (257 aa)
modBMolybdate transporter subunit; Part of the binding-protein-dependent transport system for molybdenum; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (229 aa)
modCMolybdate transporter subunit; Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Molybdate importer (TC 3.A.1.8) family. (352 aa)
ybhAPutative phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (272 aa)
moaAMolybdopterin biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa)
moaBMolybdopterin biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (170 aa)
moaCMolybdopterin biosynthesis, protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (161 aa)
moaDMolybdopterin synthase, small subunit; Function experimentally demonstrated in the studied species; enzyme. (81 aa)
moaEMolybdopterin synthase, large subunit; Function experimentally demonstrated in the studied species; enzyme. (150 aa)
moeBMolybdopterin synthase sulfurylase; Function experimentally demonstrated in the studied species; enzyme. (249 aa)
moeAMolybdopterin biosynthesis protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (411 aa)
thiMHydoxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (262 aa)
thiDBifunctional hydroxy-methylpyrimidine kinase and hydroxy-phosphomethylpyrimidine kinase; Function experimentally demonstrated in the studied species; enzyme. (266 aa)
ycfNThiamin kinase; Catalyzes the phosphorylation of thiamine to thiamine phosphate. (274 aa)
ycbXPutative 2Fe-2S cluster-containing protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (369 aa)
yiiMConserved hypothetical protein; Homologs of previously reported genes of unknown function. (224 aa)
mobAMolybdopterin-guanine dinucleotide synthase; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (194 aa)
mobBMolybdopterin-guanine dinucleotide biosynthesis protein B; Function experimentally demonstrated in the studied species; putative factor. (170 aa)
thiHThiamin biosynthesis ThiGH complex subunit; Function experimentally demonstrated in the studied species; enzyme. (377 aa)
thiGThiamin biosynthesis ThiGH complex subunit; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (256 aa)
thiSSulphur carrier protein; Function experimentally demonstrated in the studied species; carrier. (66 aa)
thiFThiamin (thiazole moiety) biosynthesis protein; Function experimentally demonstrated in the studied species; enzyme. (251 aa)
thiEThiamin phosphate synthase (thiamin phosphate pyrophosphorylase); Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (211 aa)
thiCThiamin (pyrimidine moiety) biosynthesis protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (631 aa)
rsgARibosome small subunit-dependent GTPase A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. (350 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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