STRINGSTRING
sgrR sgrR secM secM yacL yacL yacC yacC ybaJ ybaJ hha hha ybaE ybaE yajG yajG aroM aroM rcsF rcsF CAR16668.1 CAR16668.1 ybfA ybfA ybgE ybgE bssR bssR CAR17019.1 CAR17019.1 asmA asmA rcsA rcsA yecF yecF flhE flhE yobD yobD yniB yniB ydhA ydhA ydgK ydgK ydgT ydgT ydgA ydgA tus tus ydgH ydgH ydgD ydgD ynfD ynfD yciU yciU yciB yciB yciC yciC ompN ompN ydbH ydbH CAR17985.1 CAR17985.1 CAR18107.1 CAR18107.1 yceB yceB dinI dinI bssS bssS mdoC mdoC yccR yccR ycbJ ycbJ yeiB yeiB yejG yejG rcsD rcsD rcsB rcsB rcsC rcsC yfbU yfbU yfeY yfeY ypfG ypfG ypfN ypfN CAR18834.1 CAR18834.1 sseB sseB ygaC ygaC iap iap yijD yijD yiiR yiiR yiiQ yiiQ yggN yggN yqhH yqhH yhcN yhcN yhcO yhcO aaeB aaeB aaeA aaeA aaeX aaeX yhfK yhfK tsgA tsgA igaA igaA yhhN yhhN yhjG yhjG yhjJ yhjJ yiaF yiaF yicH yicH yidQ yidQ yidR yidR atpI atpI papA papA yjeI yjeI ytfB ytfB cybC cybC mdoB mdoB CAR20992.1 CAR20992.1 ytjB ytjB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sgrRDNA-binding transcriptional regulator; Activates the small RNA gene sgrS under glucose-phosphate stress conditions as well as yfdZ. Represses its own transcription under both stress and non-stress conditions. Might act as a sensor of the intracellular accumulation of phosphoglucose by binding these molecules in its C-terminal solute-binding domain. (559 aa)
secMRegulator of secA translation; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family. (170 aa)
yacLConserved hypothetical protein; Homologs of previously reported genes of unknown function; 7567469; Belongs to the UPF0231 family. (120 aa)
yacCConserved hypothetical protein; Homologs of previously reported genes of unknown function. (172 aa)
ybaJFragment of multidrug efflux system protein (part 2); Gene remnant; transporter. (124 aa)
hhaModulator of gene expression, with H-NS; Function experimentally demonstrated in the studied species; factor. (72 aa)
ybaEConserved hypothetical protein; Homologs of previously reported genes of unknown function. (566 aa)
yajGPutative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (192 aa)
aroMConserved hypothetical protein; Homologs of previously reported genes of unknown function; 3001025. (225 aa)
rcsFConserved hypothetical protein; Essential component of the Rcs signaling system, which controls transcription of numerous genes. Plays a role in signal transduction from the cell surface to the histidine kinase RcsC. May detect outer membrane defects; Belongs to the RcsF family. (134 aa)
CAR16668.1Putative Lom-like outer membrane protein of prophage; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (199 aa)
ybfAConserved hypothetical protein; Homologs of previously reported genes of unknown function. (68 aa)
ybgEConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (97 aa)
bssRBiofilm regulator; Function experimentally demonstrated in the studied species; regulator. (127 aa)
CAR17019.1Putative Lom-like outer membrane protein of prophage; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (199 aa)
asmAPutative inner membrane protein involved in outer membrane protein assembly; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor. (617 aa)
rcsADNA-binding transcriptional activator, co-regulator with RcsB; Component of the Rcs signaling system, which controls transcription of numerous genes. Binds, with RcsB, to the RcsAB box to regulate expression of genes. (207 aa)
yecFConserved hypothetical protein; Homologs of previously reported genes of unknown function; 7567469. (74 aa)
flhEConserved hypothetical protein; Homologs of previously reported genes of unknown function; 1482109, 89181349. (130 aa)
yobDConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (152 aa)
yniBConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (178 aa)
ydhAPutative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (109 aa)
ydgKConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (146 aa)
ydgTPost-transcriptional regulator; Function experimentally demonstrated in the studied species; regulator. (71 aa)
ydgAConserved hypothetical protein; Homologs of previously reported genes of unknown function. (502 aa)
tusInhibitor of replication at Ter, DNA-binding protein; Trans-acting protein required for termination of DNA replication. Binds to DNA replication terminator sequences (terA to terF) to prevent the passage of replication forks. The termination efficiency will be affected by the affinity of this protein for the terminator sequence; Belongs to the Tus family. (309 aa)
ydgHConserved hypothetical protein; Homologs of previously reported genes of unknown function. (314 aa)
ydgDPutative exported metallopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the peptidase S1B family. (273 aa)
ynfDConserved hypothetical protein; Homologs of previously reported genes of unknown function. (101 aa)
yciUConserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0263 family. (109 aa)
yciBPutative intracellular septation protein involved in cell division; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (179 aa)
yciCConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (247 aa)
ompNOuter membrane pore protein N, non-specific; Function experimentally demonstrated in the studied species; transporter. (377 aa)
ydbHConserved hypothetical protein; Homologs of previously reported genes of unknown function. (879 aa)
CAR17985.1Putative Lom-like outer membrane protein of prophage; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (199 aa)
CAR18107.1Putative Lom-like outer membrane protein of prophage; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (157 aa)
yceBPutative lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (186 aa)
dinIDNA damage-inducible protein I; Function experimentally demonstrated in the studied species; factor. (125 aa)
bssSBiofilm regulator; Function experimentally demonstrated in the studied species; regulator. (84 aa)
mdoCMembrane protein required for modification of periplasmic glucan; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane. (385 aa)
yccRConserved hypothetical protein; Homologs of previously reported genes of unknown function. (209 aa)
ycbJConserved hypothetical protein; Homologs of previously reported genes of unknown function. (297 aa)
yeiBConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (385 aa)
yejGConserved hypothetical protein; Homologs of previously reported genes of unknown function. (114 aa)
rcsDPhosphotransfer intermediate protein in two-component regulatory system with RcsBC; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB. (890 aa)
rcsBDNA-binding response regulator in two-component regulatory system with RcsC and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsB is the response regulator that binds to regulatory DNA regions. Can function both in an RcsA-dependent or RcsA-independent manner. (216 aa)
rcsCHybrid sensory kinase in two-component regulatory system with RcsB and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (933 aa)
yfbUConserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0304 family. (164 aa)
yfeYConserved hypothetical protein; Homologs of previously reported genes of unknown function; 7764507. (191 aa)
ypfGConserved hypothetical protein; Homologs of previously reported genes of unknown function. (347 aa)
ypfNConserved hypothetical protein; Homologs of previously reported genes of unknown function. (66 aa)
CAR18834.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (71 aa)
sseBRhodanase-like enzyme, sulfur transfer from thiosulfate; Function experimentally demonstrated in the studied species; enzyme. (258 aa)
ygaCConserved hypothetical protein; Homologs of previously reported genes of unknown function. (114 aa)
iapAminopeptidase in alkaline phosphatase isozyme conversion; Function experimentally demonstrated in the studied species; enzyme. (345 aa)
yijDConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (119 aa)
yiiRConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (146 aa)
yiiQConserved hypothetical protein; Homologs of previously reported genes of unknown function. (199 aa)
yggNConserved hypothetical protein; Homologs of previously reported genes of unknown function. (239 aa)
yqhHPutative outer membrane lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (85 aa)
yhcNConserved hypothetical protein; Homologs of previously reported genes of unknown function. (87 aa)
yhcOPutative barnase inhibitor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (90 aa)
aaeBP-hydroxybenzoic acid efflux system component; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell. (655 aa)
aaeAP-hydroxybenzoic acid efflux system component; Forms an efflux pump with AaeB. (310 aa)
aaeXMembrane protein of efflux system; Function experimentally demonstrated in the studied species; transporter; Belongs to the AaeX family. (67 aa)
yhfKConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (700 aa)
tsgAPutative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (393 aa)
igaAIntracellular growth attenuator protein; Function of homologous gene experimentally demonstrated in an other organism; regulator. (711 aa)
yhhNConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (208 aa)
yhjGPutative outer membrane biogenesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (691 aa)
yhjJPutative zinc-dependent peptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (498 aa)
yiaFConserved hypothetical protein; Homologs of previously reported genes of unknown function. (236 aa)
yicHConserved hypothetical protein; Homologs of previously reported genes of unknown function. (569 aa)
yidQConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (110 aa)
yidRConserved hypothetical protein; Homologs of previously reported genes of unknown function. (404 aa)
atpIATP synthase, membrane-bound accesory subunit; Function experimentally demonstrated in the studied species; enzyme. (126 aa)
papAMajor pilin protein PapA; Function experimentally demonstrated in the studied species; structure. (198 aa)
yjeIConserved hypothetical protein; Homologs of previously reported genes of unknown function. (117 aa)
ytfBPutative cell envelope opacity-associated protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure. (212 aa)
cybCSoluble cytochrome b562; Function experimentally demonstrated in the studied species; carrier. (128 aa)
mdoBFragment of putative oxidoreductase, Zn-dependent and NAD(P)-binding (partial); Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (763 aa)
CAR20992.1Putative Lom-like outer membrane protein of prophage; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (199 aa)
ytjBConserved hypothetical protein; Homologs of previously reported genes of unknown function. (214 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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