STRINGSTRING
degP degP tsx tsx phoE phoE ompX ompX CAR17225.1 CAR17225.1 lpp lpp hns hns ompW ompW CAR17865.1 CAR17865.1 yccV yccV ompA ompA ycbG ycbG ompF ompF mukB mukB mukE mukE mukF mukF ompC ompC stpA stpA btuB btuB tsx-2 tsx-2 ompL ompL yhcB yhcB yhhL yhhL yjeP yjeP trpR trpR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
degPSerine endoprotease (protease Do), membrane-associated; Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S1C family. (474 aa)
tsxFragment of putative lipoprotein (partial); Gene remnant; lipoprotein. (294 aa)
phoEOuter membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (351 aa)
ompXOuter membrane protein; Function experimentally demonstrated in the studied species; membrane component. (171 aa)
CAR17225.1Outer membrane protein N precursor (porin); Function of strongly homologous gene; membrane component. (375 aa)
lppMurein lipoprotein; Function experimentally demonstrated in the studied species; lipoprotein. (78 aa)
hnsGlobal nucleic acid-binding transcriptional dual regulator H-NS; Function experimentally demonstrated in the studied species; regulator; Belongs to the histone-like protein H-NS family. (137 aa)
ompWOuter membrane protein W; Function experimentally demonstrated in the studied species; membrane component. (212 aa)
CAR17865.1Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family. (366 aa)
yccVDNA-binding protein, hemimethylated; Involved in the degradation of certain denaturated proteins, including DnaA, during heat shock stress; Belongs to the HspQ family. (105 aa)
ompAOuter membrane protein A (3a;II*;G;d); Function experimentally demonstrated in the studied species; membrane component; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (374 aa)
ycbGConserved hypothetical protein; Required for spatial organization of the terminus region of the chromosome (Ter macrodomain) during the cell cycle. Prevents early segregation of duplicated Ter macrodomains during cell division. Binds specifically to matS, which is a 13 bp signature motif repeated within the Ter macrodomain. (150 aa)
ompFOuter membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (357 aa)
mukBFused chromosome partitioning protein: putative nucleotide hydrolase; Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division; Belongs to the SMC family. MukB subfamily. (1486 aa)
mukEProtein involved in chromosome partitioning; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Probably acts via its interaction with MukB and MukF. (225 aa)
mukFInvolved in chromosome partioning, Ca2+ binding protein; Involved in chromosome condensation, segregation and cell cycle progression. May participate in facilitating chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division. Not required for mini-F plasmid partitioning. Probably acts via its interaction with MukB and MukE. Overexpression results in anucleate cells. It has a calcium binding activity. (440 aa)
ompCOuter membrane porin protein C; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (364 aa)
stpADNA binding protein, nucleoid-associated; Function experimentally demonstrated in the studied species; regulator; Belongs to the histone-like protein H-NS family. (134 aa)
btuBVitamin B12/cobalamin outer membrane transporter; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (614 aa)
tsx-2Nucleoside channel, receptor of phage T6 and colicin K; Function experimentally demonstrated in the studied species; membrane component. (286 aa)
ompLPutative outer membrane porin L; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (230 aa)
yhcBPutative cytochrome d ubiquinol oxidase subunit III; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (132 aa)
yhhLConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (89 aa)
yjePPutative mechanosensitive channel; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (1107 aa)
trpRDNA-binding transcriptional repressor, tryptophan-binding; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon (5'- ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region. (108 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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