node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
csrA | csrD | ECIAI39_2881 | ECIAI39_3744 | Pleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small [...] | Inner membrane associated factor modulating specific RNAseE dependent RNA degradation pathways; Function experimentally demonstrated in the studied species; factor. | 0.826 |
csrA | evgS | ECIAI39_2881 | ECIAI39_2513 | Pleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small [...] | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | 0.664 |
csrA | uvrY | ECIAI39_2881 | ECIAI39_1141 | Pleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small [...] | DNA-binding response regulator in two-component regulatory system with BarA; Function experimentally demonstrated in the studied species; regulator. | 0.847 |
csrD | csrA | ECIAI39_3744 | ECIAI39_2881 | Inner membrane associated factor modulating specific RNAseE dependent RNA degradation pathways; Function experimentally demonstrated in the studied species; factor. | Pleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small [...] | 0.826 |
csrD | evgS | ECIAI39_3744 | ECIAI39_2513 | Inner membrane associated factor modulating specific RNAseE dependent RNA degradation pathways; Function experimentally demonstrated in the studied species; factor. | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | 0.958 |
csrD | uvrY | ECIAI39_3744 | ECIAI39_1141 | Inner membrane associated factor modulating specific RNAseE dependent RNA degradation pathways; Function experimentally demonstrated in the studied species; factor. | DNA-binding response regulator in two-component regulatory system with BarA; Function experimentally demonstrated in the studied species; regulator. | 0.825 |
evgA | evgS | ECIAI39_2512 | ECIAI39_2513 | DNA-binding response regulator in two-component regulatory system with EvgS; Function experimentally demonstrated in the studied species; regulator. | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | 0.999 |
evgA | narQ | ECIAI39_2512 | ECIAI39_2606 | DNA-binding response regulator in two-component regulatory system with EvgS; Function experimentally demonstrated in the studied species; regulator. | Sensory histidine kinase in two-component regulatory system with NarP (NarL); Function experimentally demonstrated in the studied species; regulator. | 0.706 |
evgA | narX | ECIAI39_2512 | ECIAI39_1560 | DNA-binding response regulator in two-component regulatory system with EvgS; Function experimentally demonstrated in the studied species; regulator. | Sensory histidine kinase in two-component regulatory system with NarL; Function experimentally demonstrated in the studied species; regulator. | 0.659 |
evgA | yhjB | ECIAI39_2512 | ECIAI39_4023 | DNA-binding response regulator in two-component regulatory system with EvgS; Function experimentally demonstrated in the studied species; regulator. | Putative DNA-binding response regulator in two-component regulatory system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.749 |
evgS | csrA | ECIAI39_2513 | ECIAI39_2881 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | Pleiotropic regulatory protein for carbon source metabolism; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small [...] | 0.664 |
evgS | csrD | ECIAI39_2513 | ECIAI39_3744 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | Inner membrane associated factor modulating specific RNAseE dependent RNA degradation pathways; Function experimentally demonstrated in the studied species; factor. | 0.958 |
evgS | evgA | ECIAI39_2513 | ECIAI39_2512 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | DNA-binding response regulator in two-component regulatory system with EvgS; Function experimentally demonstrated in the studied species; regulator. | 0.999 |
evgS | fimZ | ECIAI39_2513 | ECIAI39_0500 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | DNA-binding transcriptional regulator, isolated component of a two-component regulator system; Function experimentally demonstrated in the studied species; regulator. | 0.810 |
evgS | fnr | ECIAI39_2513 | ECIAI39_1683 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | DNA-binding transcriptional dual regulator, global regulator of anaerobic growth; Function experimentally demonstrated in the studied species; regulator. | 0.455 |
evgS | narL | ECIAI39_2513 | ECIAI39_1559 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | DNA-binding response regulator in two-component regulatory system with NarX (or NarQ); Function experimentally demonstrated in the studied species; regulator. | 0.782 |
evgS | narP | ECIAI39_2513 | ECIAI39_2331 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | DNA-binding response regulator in two-component regulatory system with NarQ or NarX; Function experimentally demonstrated in the studied species; regulator. | 0.808 |
evgS | sdiA | ECIAI39_2513 | ECIAI39_1139 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | DNA-binding transcriptional activator; Function experimentally demonstrated in the studied species; regulator. | 0.782 |
evgS | uvrY | ECIAI39_2513 | ECIAI39_1141 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | DNA-binding response regulator in two-component regulatory system with BarA; Function experimentally demonstrated in the studied species; regulator. | 0.783 |
evgS | yhjB | ECIAI39_2513 | ECIAI39_4023 | Hybrid sensory histidine kinase in two-component regulatory system with EvgA; Function experimentally demonstrated in the studied species; regulator. | Putative DNA-binding response regulator in two-component regulatory system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. | 0.782 |