(20 nodes) Mixed, incl. Dimethyl sulfoxide reductase activity, and Selenium network (Escherichia coli IAI39)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Your Input:
	selD	Selenophosphate synthase; Synthesizes selenophosphate from selenide and ATP. (347 aa)
	dmsD	Twin-argninine leader-binding protein for DmsA and TorA; Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding- maturation pathway for the substrate protein. (204 aa)
	ynfH	Oxidoreductase, membrane subunit; Function experimentally demonstrated in the studied species; membrane component. (284 aa)
	ynfG	Oxidoreductase, Fe-S subunit; Function experimentally demonstrated in the studied species; carrier. (205 aa)
	ynfF	Oxidoreductase subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (807 aa)
	ynfE	Oxidoreductase subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (808 aa)
	fdnG	Formate dehydrogenase-N, alpha subunit, nitrate-inducible; Function experimentally demonstrated in the studied genus; enzyme. (1015 aa)
	fdnH	Formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (294 aa)
	fdnI	Formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible; Function experimentally demonstrated in the studied species; carrier. (217 aa)
	dmsC	Dimethyl sulfoxide reductase, anaerobic, subunit C; Function experimentally demonstrated in the studied species; enzyme. (287 aa)
	dmsB	Dimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme. (205 aa)
	dmsA	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (814 aa)
	fdhD	Formate dehydrogenase formation protein; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (277 aa)
	fdoG	Formate dehydrogenase-O, large subunit; Function experimentally demonstrated in the studied genus; enzyme. (1016 aa)
	fdoH	Formate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (300 aa)
	fdoI	Formate dehydrogenase-O, cytochrome b556 subunit; Function experimentally demonstrated in the studied species; carrier. (211 aa)
	fdhE	Formate dehydrogenase formation protein; Necessary for formate dehydrogenase activity. Belongs to the FdhE family. (309 aa)
	yiaI	Putative hydrogenase, 4Fe-4S ferredoxin-type component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (157 aa)
	selB	selenocysteinyl-tRNA-specific translation factor; Function experimentally demonstrated in the studied species; factor. (614 aa)
	selA	Selenocysteine synthase; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis; Belongs to the SelA family. (463 aa)

Your Current Organism:

Escherichia coli IAI39

NCBI taxonomy Id: 585057
Other names: E. coli IAI39

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
dmsA	dmsB	ECIAI39_2254	ECIAI39_2253	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Dimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme.	0.999
dmsA	dmsC	ECIAI39_2254	ECIAI39_2252	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Dimethyl sulfoxide reductase, anaerobic, subunit C; Function experimentally demonstrated in the studied species; enzyme.	0.998
dmsA	dmsD	ECIAI39_2254	ECIAI39_1467	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Twin-argninine leader-binding protein for DmsA and TorA; Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding- maturation pathway for the substrate protein.	0.990
dmsA	fdnG	ECIAI39_2254	ECIAI39_1736	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Formate dehydrogenase-N, alpha subunit, nitrate-inducible; Function experimentally demonstrated in the studied genus; enzyme.	0.533
dmsA	fdnH	ECIAI39_2254	ECIAI39_1738	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.	0.744
dmsA	fdnI	ECIAI39_2254	ECIAI39_1739	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible; Function experimentally demonstrated in the studied species; carrier.	0.641
dmsA	fdoG	ECIAI39_2254	ECIAI39_3104	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Formate dehydrogenase-O, large subunit; Function experimentally demonstrated in the studied genus; enzyme.	0.532
dmsA	fdoH	ECIAI39_2254	ECIAI39_3106	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Formate dehydrogenase-O, Fe-S subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.	0.743
dmsA	fdoI	ECIAI39_2254	ECIAI39_3107	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Formate dehydrogenase-O, cytochrome b556 subunit; Function experimentally demonstrated in the studied species; carrier.	0.641
dmsA	yiaI	ECIAI39_2254	ECIAI39_4085	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Putative hydrogenase, 4Fe-4S ferredoxin-type component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.	0.448
dmsA	ynfF	ECIAI39_2254	ECIAI39_1470	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Oxidoreductase subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.488
dmsA	ynfG	ECIAI39_2254	ECIAI39_1469	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Oxidoreductase, Fe-S subunit; Function experimentally demonstrated in the studied species; carrier.	0.891
dmsA	ynfH	ECIAI39_2254	ECIAI39_1468	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	Oxidoreductase, membrane subunit; Function experimentally demonstrated in the studied species; membrane component.	0.816
dmsB	dmsA	ECIAI39_2253	ECIAI39_2254	Dimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme.	Dimethyl sulfoxide reductase, anaerobic, subunit A; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.	0.999
dmsB	dmsC	ECIAI39_2253	ECIAI39_2252	Dimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme.	Dimethyl sulfoxide reductase, anaerobic, subunit C; Function experimentally demonstrated in the studied species; enzyme.	0.999
dmsB	dmsD	ECIAI39_2253	ECIAI39_1467	Dimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme.	Twin-argninine leader-binding protein for DmsA and TorA; Required for biogenesis/assembly of DMSO reductase, but not for the interaction of the DmsA signal peptide with the Tat system. May be part of a chaperone cascade complex that facilitates a folding- maturation pathway for the substrate protein.	0.575
dmsB	fdnG	ECIAI39_2253	ECIAI39_1736	Dimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme.	Formate dehydrogenase-N, alpha subunit, nitrate-inducible; Function experimentally demonstrated in the studied genus; enzyme.	0.822
dmsB	fdnH	ECIAI39_2253	ECIAI39_1738	Dimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme.	Formate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.	0.602
dmsB	fdnI	ECIAI39_2253	ECIAI39_1739	Dimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme.	Formate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible; Function experimentally demonstrated in the studied species; carrier.	0.826
dmsB	fdoG	ECIAI39_2253	ECIAI39_3104	Dimethyl sulfoxide reductase, anaerobic, subunit B; Function experimentally demonstrated in the studied species; enzyme.	Formate dehydrogenase-O, large subunit; Function experimentally demonstrated in the studied genus; enzyme.	0.820