STRINGSTRING
mak mak nagE nagE ybhK ybhK cpsG cpsG manZ manZ manY manY manX manX malX malX manA manA dgsA dgsA ptsG ptsG fruA fruA fruK fruK fruB fruB ptsH ptsH ptsI ptsI crr crr CAR19082.1 CAR19082.1 frwD frwD frwB frwB frwC frwC ptsA ptsA frvA frvA frvB frvB frvX frvX frvR frvR ptsP ptsP ptsN ptsN yhbJ yhbJ npr npr CAR20286.1 CAR20286.1 CAR20287.1 CAR20287.1 CAR20288.1 CAR20288.1 CAR20289.1 CAR20289.1 CAR20290.1 CAR20290.1 CAR20291.1 CAR20291.1 CAR20292.1 CAR20292.1 CAR20390.1 CAR20390.1 CAR20391.1 CAR20391.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
makManno(fructo)kinase; Function experimentally demonstrated in the studied species; enzyme. (302 aa)
nagEFused N-acetyl glucosamine specific PTS enzymes: IIC component; Function experimentally demonstrated in the studied species; transporter. (629 aa)
ybhKPutative transferase with NAD(P)-binding Rossmann-fold domain; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. (302 aa)
cpsGPhosphomannomutase; Function experimentally demonstrated in the studied species; enzyme. (456 aa)
manZMannose-specific enzyme IID component of PTS; Function experimentally demonstrated in the studied species; transporter. (286 aa)
manYMannose-specific enzyme IIC component of PTS; Function experimentally demonstrated in the studied species; transporter. (266 aa)
manXFused mannose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter. (323 aa)
malXFused maltose and glucose-specific PTS enzymes: IIB and IIC components; Function experimentally demonstrated in the studied species; transporter. (530 aa)
manAMannose-6-phosphate isomerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the mannose-6-phosphate isomerase type 1 family. (391 aa)
dgsADNA-binding transcriptional repressor; Function experimentally demonstrated in the studied species; regulator. (406 aa)
ptsGFragment of ferric-rhodotorulic acid outer membrane transporter (part 2); Gene remnant; transporter. (477 aa)
fruAFused fructose-specific PTS enzymes: IIBcomponent; Function experimentally demonstrated in the studied species; transporter. (563 aa)
fruKFructose-1-phosphate kinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family. (312 aa)
fruBFused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter. (376 aa)
ptsHPhosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr); Function experimentally demonstrated in the studied species; transporter. (85 aa)
ptsIPEP-protein phosphotransferase of PTS system (enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (575 aa)
crrGlucose-specific enzyme IIA component of PTS; Function experimentally demonstrated in the studied species; transporter. (169 aa)
CAR19082.1Fructokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. (306 aa)
frwDEnzyme IIB component of PTS; Function of strongly homologous gene; transporter. (113 aa)
frwBPutative enzyme IIB component of PTS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (106 aa)
frwCEnzyme IIC component of PTS; Function of strongly homologous gene; putative transporter. (359 aa)
ptsAFused putative PTS enzymes: Hpr component; Function of strongly homologous gene; transporter. (833 aa)
frvAEnzyme IIA component of PTS; Function of strongly homologous gene; transporter. (148 aa)
frvBFused putative PTS enzymes: IIB component; Function of strongly homologous gene; transporter. (483 aa)
frvXPutative endo-1,4-beta-glucanase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (356 aa)
frvRPutative regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (582 aa)
ptsPFused PTS enzyme: PEP-protein phosphotransferase (enzyme I); Function experimentally demonstrated in the studied species; transporter; Belongs to the PEP-utilizing enzyme family. (748 aa)
ptsNSugar-specific enzyme IIA component of PTS; Function experimentally demonstrated in the studied species; transporter. (163 aa)
yhbJConserved hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily. (284 aa)
nprPhosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr); Function experimentally demonstrated in the studied species; transporter. (90 aa)
CAR20286.1Putative sugar kinase/transcriptional regulator. ATPase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (321 aa)
CAR20287.1Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (286 aa)
CAR20288.1Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (283 aa)
CAR20289.1Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (363 aa)
CAR20290.1Putative phosphotransferase system, fructose-specific IIB subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (104 aa)
CAR20291.1Putative phosphotransferase system (PTS), fructose-specific IIA component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (156 aa)
CAR20292.1Putative PTS system transcriptional antiterminator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (517 aa)
CAR20390.16-phospho-glucosidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (440 aa)
CAR20391.1Putative PTS system alpha-glucoside-specific EIICB component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (625 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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