STRINGSTRING
speD speD speE speE ldcC ldcC potE potE speF speF speG speG ynfB ynfB ynfA ynfA speB speB speC speC ygjG ygjG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
speDS-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (264 aa)
speESpermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (288 aa)
ldcCLysine decarboxylase 2, constitutive; Function experimentally demonstrated in the studied species; enzyme. (713 aa)
potEPutrescine/proton symporter: putrescine/ornithine antiporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family. (439 aa)
speFOrnithine decarboxylase isozyme, inducible; Function experimentally demonstrated in the studied species; enzyme. (732 aa)
speGSpermidine N1-acetyltransferase; Function experimentally demonstrated in the studied species; enzyme. (186 aa)
ynfBConserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the UPF0482 family. (113 aa)
ynfAConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (108 aa)
speBAgmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. (306 aa)
speCOrnithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme. (711 aa)
ygjGPutrescine:2-oxoglutaric acid aminotransferase, PLP-dependent; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (468 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.