(6 nodes) Polyamine biosynthesis, and Ornithine decarboxylase activity network (Escherichia coli IAI39)

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Your Input:
	speD	S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily. (264 aa)
	speE	Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (288 aa)
	potE	Putrescine/proton symporter: putrescine/ornithine antiporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family. (439 aa)
	speF	Ornithine decarboxylase isozyme, inducible; Function experimentally demonstrated in the studied species; enzyme. (732 aa)
	speB	Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily. (306 aa)
	speC	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme. (711 aa)

Your Current Organism:

Escherichia coli IAI39

NCBI taxonomy Id: 585057
Other names: E. coli IAI39

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
potE	speC	ECIAI39_0650	ECIAI39_3389	Putrescine/proton symporter: putrescine/ornithine antiporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme.	0.818
potE	speF	ECIAI39_0650	ECIAI39_0651	Putrescine/proton symporter: putrescine/ornithine antiporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.	Ornithine decarboxylase isozyme, inducible; Function experimentally demonstrated in the studied species; enzyme.	0.987
speB	speC	ECIAI39_3356	ECIAI39_3389	Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme.	0.981
speB	speD	ECIAI39_3356	ECIAI39_0120	Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.	S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.	0.661
speB	speE	ECIAI39_3356	ECIAI39_0121	Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.	Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	0.973
speB	speF	ECIAI39_3356	ECIAI39_0651	Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.	Ornithine decarboxylase isozyme, inducible; Function experimentally demonstrated in the studied species; enzyme.	0.962
speC	potE	ECIAI39_3389	ECIAI39_0650	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme.	Putrescine/proton symporter: putrescine/ornithine antiporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.	0.818
speC	speB	ECIAI39_3389	ECIAI39_3356	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme.	Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.	0.981
speC	speD	ECIAI39_3389	ECIAI39_0120	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme.	S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.	0.653
speC	speE	ECIAI39_3389	ECIAI39_0121	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme.	Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	0.980
speC	speF	ECIAI39_3389	ECIAI39_0651	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme.	Ornithine decarboxylase isozyme, inducible; Function experimentally demonstrated in the studied species; enzyme.	0.901
speD	speB	ECIAI39_0120	ECIAI39_3356	S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.	Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.	0.661
speD	speC	ECIAI39_0120	ECIAI39_3389	S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme.	0.653
speD	speE	ECIAI39_0120	ECIAI39_0121	S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.	Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	0.999
speD	speF	ECIAI39_0120	ECIAI39_0651	S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.	Ornithine decarboxylase isozyme, inducible; Function experimentally demonstrated in the studied species; enzyme.	0.653
speE	speB	ECIAI39_0121	ECIAI39_3356	Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	Agmatinase; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.	0.973
speE	speC	ECIAI39_0121	ECIAI39_3389	Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	Ornithine decarboxylase, constitutive; Function experimentally demonstrated in the studied species; enzyme.	0.980
speE	speD	ECIAI39_0121	ECIAI39_0120	Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	S-adenosylmethionine decarboxylase; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily.	0.999
speE	speF	ECIAI39_0121	ECIAI39_0651	Spermidine synthase (putrescine aminopropyltransferase); Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	Ornithine decarboxylase isozyme, inducible; Function experimentally demonstrated in the studied species; enzyme.	0.964
speF	potE	ECIAI39_0651	ECIAI39_0650	Ornithine decarboxylase isozyme, inducible; Function experimentally demonstrated in the studied species; enzyme.	Putrescine/proton symporter: putrescine/ornithine antiporter; Catalyzes both the uptake and excretion of putrescine. The uptake of putrescine is dependent on the membrane potential and the excretion involves putrescine-ornithine antiporter activity. Belongs to the amino acid-polyamine-organocation (APC) superfamily. Basic amino acid/polyamine antiporter (APA) (TC 2.A.3.2) family.	0.987