8 items (Escherichia coli IAI39) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Predicted Interactions

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Your Input:
	pgsA	Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (182 aa)
	cls	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (486 aa)
	pgpB	Function experimentally demonstrated in the studied species; enzyme. (254 aa)
	ymdC	Putative hydrolase; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily. (473 aa)
	yfhB	Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (211 aa)
	pgpA	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (172 aa)
	pssA	Phosphatidylserine synthase (CDP-diacylglycerol-serine O-phosphatidyltransferase); Function experimentally demonstrated in the studied species; enzyme. (451 aa)
	ybhO	Cardiolipin synthase 2; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (413 aa)

Your Current Organism:

Escherichia coli IAI39

NCBI taxonomy Id: 585057
Other names: E. coli IAI39

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
cls	pgpA	ECIAI39_1584	ECIAI39_0258	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).	0.926
cls	pgpB	ECIAI39_1584	ECIAI39_1619	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	Function experimentally demonstrated in the studied species; enzyme.	0.912
cls	pgsA	ECIAI39_1584	ECIAI39_1143	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.854
cls	pssA	ECIAI39_1584	ECIAI39_2793	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	Phosphatidylserine synthase (CDP-diacylglycerol-serine O-phosphatidyltransferase); Function experimentally demonstrated in the studied species; enzyme.	0.687
cls	ybhO	ECIAI39_1584	ECIAI39_0765	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	Cardiolipin synthase 2; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	0.931
cls	yfhB	ECIAI39_1584	ECIAI39_2764	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.914
cls	ymdC	ECIAI39_1584	ECIAI39_2117	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	Putative hydrolase; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily.	0.930
pgpA	cls	ECIAI39_0258	ECIAI39_1584	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	0.926
pgpA	pgpB	ECIAI39_0258	ECIAI39_1619	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).	Function experimentally demonstrated in the studied species; enzyme.	0.982
pgpA	pgsA	ECIAI39_0258	ECIAI39_1143	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).	Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.965
pgpA	pssA	ECIAI39_0258	ECIAI39_2793	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).	Phosphatidylserine synthase (CDP-diacylglycerol-serine O-phosphatidyltransferase); Function experimentally demonstrated in the studied species; enzyme.	0.502
pgpA	ybhO	ECIAI39_0258	ECIAI39_0765	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).	Cardiolipin synthase 2; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	0.926
pgpA	yfhB	ECIAI39_0258	ECIAI39_2764	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.982
pgpA	ymdC	ECIAI39_0258	ECIAI39_2117	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).	Putative hydrolase; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily.	0.936
pgpB	cls	ECIAI39_1619	ECIAI39_1584	Function experimentally demonstrated in the studied species; enzyme.	Cardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	0.912
pgpB	pgpA	ECIAI39_1619	ECIAI39_0258	Function experimentally demonstrated in the studied species; enzyme.	Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG).	0.982
pgpB	pgsA	ECIAI39_1619	ECIAI39_1143	Function experimentally demonstrated in the studied species; enzyme.	Phosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.	0.923
pgpB	ybhO	ECIAI39_1619	ECIAI39_0765	Function experimentally demonstrated in the studied species; enzyme.	Cardiolipin synthase 2; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.	0.912
pgpB	yfhB	ECIAI39_1619	ECIAI39_2764	Function experimentally demonstrated in the studied species; enzyme.	Conserved hypothetical protein; Homologs of previously reported genes of unknown function.	0.985
pgpB	ymdC	ECIAI39_1619	ECIAI39_2117	Function experimentally demonstrated in the studied species; enzyme.	Putative hydrolase; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily.	0.917