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mraY mraY entD entD citG citG ybhO ybhO cobS cobS pgsA pgsA ynjF ynjF cls cls ynbA ynbA ymdC ymdC yfbF yfbF acpS acpS pssA pssA rfe rfe acpT acpT yieE yieE mdoB mdoB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mraYphospho-N-acetylmuramoyl-pentapeptide transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (360 aa)
entDPhosphopantetheinyltransferase component of enterobactin synthase multienzyme complex; Function experimentally demonstrated in the studied species; enzyme; Belongs to the P-Pant transferase superfamily. (209 aa)
citGtriphosphoribosyl-dephospho-CoA transferase; Catalyzes the formation of 2-(5''-triphosphoribosyl)-3'- dephosphocoenzyme-A, the precursor of the prosthetic group of the holo- acyl carrier protein (gamma chain) of citrate lyase, from ATP and dephospho-CoA; Belongs to the CitG/MdcB family. (292 aa)
ybhOCardiolipin synthase 2; Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (413 aa)
cobSCobalamin 5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (247 aa)
pgsAPhosphatidylglycerophosphate synthetase; This protein catalyzes the committed step to the synthesis of the acidic phospholipids; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (182 aa)
ynjFPutative phosphatidyl transferase, inner membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; membrane component; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (206 aa)
clsCardiolipin synthase 1; Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol. (486 aa)
ynbAConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (203 aa)
ymdCPutative hydrolase; Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) from phosphatidylglycerol (PG) and phosphatidylethanolamine (PE); Belongs to the phospholipase D family. Cardiolipin synthase subfamily. ClsC sub-subfamily. (473 aa)
yfbFUndecaprenyl phosphate-L-Ara4FN transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. (322 aa)
acpSHolo-[acyl-carrier-protein] synthase 1; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (126 aa)
pssAPhosphatidylserine synthase (CDP-diacylglycerol-serine O-phosphatidyltransferase); Function experimentally demonstrated in the studied species; enzyme. (451 aa)
rfeUDP-GlcNAc:undecaprenylphosphate GlcNAc-1-phosphate transferase; Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP-C55). (367 aa)
acpTHolo-(acyl carrier protein) synthase 2; Function experimentally demonstrated in the studied species; enzyme; Belongs to the P-Pant transferase superfamily. (195 aa)
yieEPutative phosphopantetheinyl transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (253 aa)
mdoBFragment of putative oxidoreductase, Zn-dependent and NAD(P)-binding (partial); Transfers a phosphoglycerol residue from phosphatidylglycerol to the membrane-bound nascent glucan backbones; Belongs to the OpgB family. (763 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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