STRINGSTRING
metQ metQ ybbM ybbM ytjA ytjA CAR20993.1 CAR20993.1 yjiY yjiY yjhA yjhA fecR fecR fecA fecA yjgQ yjgQ yjgP yjgP ytfR ytfR ytfN ytfN ytfM ytfM yjeT yjeT hflC hflC hflK hflK frdD frdD fxsA fxsA tia-2 tia-2 dcuS dcuS melB melB phnE phnE actP actP lamB lamB malK malK malE malE malF malF malG malG CAR20522.1 CAR20522.1 CAR20521.1 CAR20521.1 CAR20520.1 CAR20520.1 CAR20519.1 CAR20519.1 secE secE rbsC rbsC rbsA rbsA pstC pstC yidC yidC yidD yidD dgoT dgoT cbrA cbrA emrD emrD uhpC uhpC yicO yicO CAR20324.1 CAR20324.1 CAR20323.1 CAR20323.1 tia tia yicE yicE mtlA mtlA xylG xylG dctA dctA yhiP yhiP ugpB ugpB ugpA ugpA ugpE ugpE ugpC ugpC glpD glpD glpG glpG envZ envZ tsgA tsgA kefG kefG mscL mscL acrE acrE yhdP yhdP lptB lptB yrbK yrbK yrbE yrbE yrbD yrbD agaB agaB CAR19751.1 CAR19751.1 agaV agaV bacA bacA htrG htrG tolC tolC yghB yghB exbB exbB exbD exbD pitB pitB CAR19592.1 CAR19592.1 CAR19591.1 CAR19591.1 kpsD kpsD shiF shiF CAR19470.1 CAR19470.1 CAR19463.1 CAR19463.1 CAR19462.1 CAR19462.1 mscS mscS yggE yggE ygfX ygfX ygfU ygfU ygfO ygfO araE araE lgt lgt fucP fucP rarD rarD pldA pldA tatA tatA tatB tatB tatC tatC trkH trkH kdgT kdgT cpxA cpxA sbp sbp ftsN ftsN tsx-2 tsx-2 argH argH btuB btuB CAR19083.1 CAR19083.1 ygcO ygcO ygcN ygcN emrA emrA ygaH ygaH proX proX proW proW proV proV ygaP ygaP gabP gabP yfiK yfiK lepB lepB yfhB yfhB yfgA yfgA yfgM yfgM uraA uraA cysP cysP cysU cysU cysW cysW cysA cysA crr crr cysZ cysZ nupC nupC emrK emrK nuoA nuoA nuoB nuoB nuoE nuoE nuoG nuoG nuoH nuoH nuoI nuoI nuoJ nuoJ nuoK nuoK nuoL nuoL nuoM nuoM nuoN nuoN elaB elaB rcsC rcsC yojI yojI ccmF ccmF aqpZ aqpZ macA macA macB macB cydC cydC cydD cydD ftsK ftsK focA focA msbA msbA ompF ompF pqiA pqiA ompA ompA yccA yccA hyaC hyaC putP putP efeU efeU efeO efeO pgaA pgaA csgG csgG csgF csgF csgE csgE mdoH mdoH mdtG mdtG mviN mviN ptsG ptsG lolC lolC potC potC potB potB potA potA CAR18103.1 CAR18103.1 CAR18056.1 CAR18056.1 CAR18054.1 CAR18054.1 sitD sitD sitC sitC sitB sitB dsbB dsbB CAR17984.1 CAR17984.1 CAR17982.1 CAR17982.1 eamA eamA CAR17961.1 CAR17961.1 lsrB lsrB CAR17896.1 CAR17896.1 yddB yddB fdnI fdnI fdnH fdnH yddG yddG CAR17865.1 CAR17865.1 ydaN ydaN ompG ompG ycjV ycjV CAR17764.1 CAR17764.1 yciS yciS pgpB pgpB yciB yciB tonB tonB narI narI narH narH narG narG narK narK CAR17664.1 CAR17664.1 clcB clcB pntB pntB pntA pntA blr blr ydgR ydgR ydiS ydiS ydiT ydiT btuD btuD btuC btuC ynjD ynjD sppA sppA manX manX manY manY manZ manZ htpX htpX yebS yebS yebT yebT znuC znuC motB motB motA motA araH araH CAR17225.1 CAR17225.1 fyuA fyuA wcaJ wcaJ wzc wzc wza wza yegK yegK mdtA mdtA CAR17020.1 CAR17020.1 yehX yehX yehZ yehZ potI potI potH potH potG potG cmr cmr fiu fiu ybhS ybhS ybhR ybhR modF modF tolR tolR tolQ tolQ cydA cydA ybgH ybgH kdpA kdpA kdpB kdpB kdpC kdpC lnt lnt dacA dacA crcB crcB fepA fepA cusA cusA CAR16671.1 CAR16671.1 CAR16669.1 CAR16669.1 nhaA nhaA lspA lspA fixC fixC fixX fixX kefF kefF kefC kefC ftsL ftsL ftsW ftsW ftsQ ftsQ secA secA aroP aroP gcd gcd yadI yadI folK folK mrcB mrcB fhuC fhuC fhuB fhuB btuF btuF amtB amtB ppiD ppiD cyoC cyoC cyoD cyoD yajR yajR pgpA pgpA tsx tsx yajC yajC phoR phoR sbmA sbmA lacY lacY phoE phoE mbhA mbhA metN metN metI metI
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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metQDL-methionine transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the nlpA lipoprotein family. (271 aa)
ybbMPutative permease of an ABC transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (259 aa)
ytjAConserved hypothetical protein; Homologs of previously reported genes of unknown function. (59 aa)
CAR20993.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function; extrachromosomal origin. (685 aa)
yjiYConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (716 aa)
yjhAN-acetylnuraminic acid outer membrane channel protein; Function experimentally demonstrated in the studied species; transporter. (238 aa)
fecRTransmembrane signal transducer for ferric citrate transport; Function experimentally demonstrated in the studied species; regulator. (317 aa)
fecAFerric citrate outer membrane transporter; Function experimentally demonstrated in the studied species; transporter. (774 aa)
yjgQConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (360 aa)
yjgPConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (366 aa)
ytfRPutative sugar transporter subunit: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (500 aa)
ytfNConserved hypothetical protein; Homologs of previously reported genes of unknown function. (1259 aa)
ytfMConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (577 aa)
yjeTConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (65 aa)
hflCModulator for HflB protease specific for phage lambda cII repressor; HflC and HflK help govern the stability of phage lambda cII protein, and thereby control the lysogenization frequency of phage lambda. HflKC inhibits the SecY-degrading activity of FtsH, possibly helping quality control of integral membrane proteins. (334 aa)
hflKModulator for HflB protease specific for phage lambda cII repressor; HflC and HflK could encode or regulate a protease. (419 aa)
frdDFumarate reductase (anaerobic), membrane anchor subunit; Seems to be involved in the anchoring of the catalytic components of the fumarate reductase complex to the cytoplasmic membrane. (119 aa)
fxsAInner membrane protein; Function experimentally demonstrated in the studied species; membrane component. (158 aa)
tia-2Tia invasion determinant; Function experimentally demonstrated in the studied species; factor. (251 aa)
dcuSTwo-component system, CitB family, sensor histidine kinase DcuS; Function experimentally demonstrated in the studied species; regulator. (543 aa)
melBMelibiose:sodium symporter; Function experimentally demonstrated in the studied species; transporter. (469 aa)
phnEPhosphonates transport system, permease protein; Function of strongly homologous gene; transporter. (259 aa)
actPAcetate transporter; Transports acetate; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (549 aa)
lamBMaltose outer membrane porin (maltoporin); Involved in the transport of maltose and maltodextrins. Belongs to the porin LamB (TC 1.B.3) family. (446 aa)
malKFused maltose transport subunit, ATP-binding component of ABC superfamily; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Maltooligosaccharide importer (TC 3.A.1.1.1) family. (371 aa)
malEMaltose transporter subunit; Part of the ABC transporter complex MalEFGK involved in maltose/maltodextrin import. Binds maltose and higher maltodextrins. Belongs to the bacterial solute-binding protein 1 family. (396 aa)
malFMaltose transporter subunit; Function experimentally demonstrated in the studied species; transporter. (514 aa)
malGMaltose transporter subunit; Function experimentally demonstrated in the studied species; transporter. (296 aa)
CAR20522.1Sorbose-specific phosphotransferase enzyme IIA component (PTS system); Function of homologous gene experimentally demonstrated in an other organism; transporter. (135 aa)
CAR20521.1Sorbose-specific phosphotransferase enzyme IIB component (PTS system); Function of homologous gene experimentally demonstrated in an other organism; transporter. (164 aa)
CAR20520.1Sorbose permease IIC component (PTS system); Function of homologous gene experimentally demonstrated in an other organism; transporter. (265 aa)
CAR20519.1Sorbose permease IID component; Function of homologous gene experimentally demonstrated in an other organism; transporter. (284 aa)
secEPreprotein translocase membrane subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. (127 aa)
rbsCD-ribose transporter subunit; Function experimentally demonstrated in the studied species; transporter; Belongs to the binding-protein-dependent transport system permease family. (321 aa)
rbsAFused D-ribose transporter subunits of ABC superfamily: ATP-binding components; Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Ribose importer (TC 3.A.1.2.1) family. (501 aa)
pstCPhosphate transporter subunit; Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (319 aa)
yidCCytoplasmic insertase into membrane protein, Sec system; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (548 aa)
yidDConserved hypothetical protein; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (85 aa)
dgoTD-galactonate transporter; Function experimentally demonstrated in the studied species; transporter. (430 aa)
cbrAPutative oxidoreductase with FAD/NAD(P)-binding domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (354 aa)
emrDMultidrug efflux system protein; Function experimentally demonstrated in the studied species; transporter. (394 aa)
uhpCMembrane protein regulates uhpT expression; Function experimentally demonstrated in the studied species; regulator. (439 aa)
yicOPutative xanthine/uracil permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (444 aa)
CAR20324.1Putative multidrug resistance protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (111 aa)
CAR20323.1Putative membrane transport protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (133 aa)
tiaTia invasion determinant; Function experimentally demonstrated in the studied species; factor. (251 aa)
yicEPutative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (463 aa)
mtlAFused mannitol-specific PTS enzymes: IIA components; Function experimentally demonstrated in the studied species; transporter. (637 aa)
xylGFused D-xylose transporter subunits of ABC superfamily: ATP-binding components; Part of the ABC transporter complex XylFGH involved in xylose import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Xylose importer (TC 3.A.1.2.4) family. (513 aa)
dctAC4-dicarboxylic acid, orotate and citrate transporter; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate from the periplasm across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (428 aa)
yhiPTransporter; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpB subfamily. (489 aa)
ugpBGlycerol-3-phosphate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (438 aa)
ugpAGlycerol-3-phosphate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (295 aa)
ugpEGlycerol-3-phosphate transporter subunit; Part of the binding-protein-dependent transport system for sn-glycerol-3-phosphate; probably responsible for the translocation of the substrate across the membrane. (281 aa)
ugpCGlycerol-3-phosphate transporter subunit; Part of the ABC transporter complex UgpABCE involved in sn- glycerol-3-phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. sn-glycerol-3- phosphate importer (TC 3.A.1.1.3) family. (356 aa)
glpDSn-glycerol-3-phosphate dehydrogenase, aerobic, FAD/NAD(P)-binding; Function experimentally demonstrated in the studied species; enzyme; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (501 aa)
glpGPutative intramembrane serine protease; Rhomboid-type serine protease that catalyzes intramembrane proteolysis. (276 aa)
envZSensory histidine kinase in two-component regulatory system with OmpR; Function experimentally demonstrated in the studied species; regulator. (450 aa)
tsgAPutative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (393 aa)
kefGFragment of potassium:proton antiporter (part 1); Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB. (184 aa)
mscLMechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (136 aa)
acrECytoplasmic membrane lipoprotein; Function experimentally demonstrated in the studied species; lipoprotein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (385 aa)
yhdPConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (1266 aa)
lptBPutative lipopolysaccharide transport protein B: ATP-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (241 aa)
yrbKConserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family. (191 aa)
yrbEToluene transporter subunit: membrane component of ABC superfamily; Function of strongly homologous gene; transporter. (260 aa)
yrbDToluene transporter subunit: membrane component of ABC superfamily; Function of strongly homologous gene; transporter. (183 aa)
agaBN-acetylgalactosamine-specific enzyme IIB component of PTS; Function experimentally demonstrated in the studied species; transporter. (158 aa)
CAR19751.1N-acetylgalactosamine PTS system EIIA component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (144 aa)
agaVN-acetylgalactosamine-specific enzyme IIB component of PTS; Function experimentally demonstrated in the studied species; transporter. (157 aa)
bacAUndecaprenyl pyrophosphate phosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (273 aa)
htrGPutative signal transduction protein (SH3 domain); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (206 aa)
tolCTransport channel; Function experimentally demonstrated in the studied species; transporter. (493 aa)
yghBConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (219 aa)
exbBMembrane spanning protein in TonB-ExbB-ExbD complex; Function experimentally demonstrated in the studied species; membrane component. (244 aa)
exbDMembrane spanning protein in TonB-ExbB-ExbD complex; Function experimentally demonstrated in the studied species; membrane component. (141 aa)
pitBFragment of conserved hypothetical protein; Gene remnant. (499 aa)
CAR19592.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (356 aa)
CAR19591.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (359 aa)
kpsDPolysialic acid transport protein precursor; Function experimentally demonstrated in the studied species; transporter. (559 aa)
shiFPutative membrane transport protein, major facilitator superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (397 aa)
CAR19470.1Putative membrane protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (314 aa)
CAR19463.1Putative ATP-binding protein of ABC transport system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (236 aa)
CAR19462.1Putative ATP-binding protein of ABC transport system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (227 aa)
mscSMechanosensitive channel; Function experimentally demonstrated in the studied species; transporter. (286 aa)
yggEConserved hypothetical protein; Homologs of previously reported genes of unknown function. (246 aa)
ygfXConserved hypothetical protein; Homologs of previously reported genes of unknown function. (135 aa)
ygfUTransporter; Function of strongly homologous gene; transporter. (482 aa)
ygfOPutative transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (466 aa)
araEArabinose transporter; Function experimentally demonstrated in the studied species; transporter; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (472 aa)
lgtPhosphatidylglycerol-prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (291 aa)
fucPL-fucose transporter; Function experimentally demonstrated in the studied species; transporter. (438 aa)
rarDPutative chloramphenicol resistance permease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (296 aa)
pldAOuter membrane phospholipase A; Hydrolysis of phosphatidylcholine with phospholipase A2 (EC 3.1.1.4) and phospholipase A1 (EC 3.1.1.32) activities. Belongs to the phospholipase A1 family. (289 aa)
tatATatABCE protein translocation system subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (89 aa)
tatBTatABCE protein translocation system subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. (171 aa)
tatCTatABCE protein translocation system subunit; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. (258 aa)
trkHPotassium transporter; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (483 aa)
kdgT2-keto-3-deoxy-D-gluconate transporter; The 2-keto-3-deoxygluconate permease transports the degraded pectin products into the bacterial cell, where they serve as carbon and energy sources. This is a hydrogen coupled transport system. Belongs to the KdgT transporter family. (327 aa)
cpxASensory histidine kinase in two-component regulatory system with CpxR; Function experimentally demonstrated in the studied species; regulator. (457 aa)
sbpSulfate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (329 aa)
ftsNEssential cell division protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases. (319 aa)
tsx-2Nucleoside channel, receptor of phage T6 and colicin K; Function experimentally demonstrated in the studied species; membrane component. (286 aa)
argHArgininosuccinate lyase; Function experimentally demonstrated in the studied species; enzyme. (457 aa)
btuBVitamin B12/cobalamin outer membrane transporter; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans- periplasmic membrane protein TonB; Belongs to the TonB-dependent receptor family. BtuB (TC 1.B.14.3.1) subfamily. (614 aa)
CAR19083.1Sucrose porin precursor; Function of strongly homologous gene; membrane component. (505 aa)
ygcOPutative 4Fe-4S cluster-containing protein; Could be a 3Fe-4S cluster-containing protein. (86 aa)
ygcNPutative oxidoreductase with FAD/NAD(P)-binding domain; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (423 aa)
emrAMultidrug efflux system; Function experimentally demonstrated in the studied species; transporter. (390 aa)
ygaHConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (111 aa)
proXGlycine betaine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (330 aa)
proWGlycine betaine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (354 aa)
proVGlycine betaine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (400 aa)
ygaPConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative enzyme. (174 aa)
gabPGamma-aminobutyrate transporter; Function experimentally demonstrated in the studied species; transporter. (466 aa)
yfiKFragment of putative DNA-binding transcriptional regulator (part 1); Gene remnant; putative regulator. (195 aa)
lepBLeader peptidase (signal peptidase I); Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S26 family. (324 aa)
yfhBConserved hypothetical protein; Homologs of previously reported genes of unknown function. (211 aa)
yfgAConserved hypothetical protein; Cytoskeletal protein that is involved in cell-shape control through regulation of the length of the long axis. (336 aa)
yfgMConserved hypothetical protein; Homologs of previously reported genes of unknown function. (206 aa)
uraAUracil transporter; Function experimentally demonstrated in the studied species; transporter. (429 aa)
cysPThiosulfate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (338 aa)
cysUSulfate/thiosulfate transporter subunit; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (277 aa)
cysWSulfate/thiosulfate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (291 aa)
cysASulfate/thiosulfate transporter subunit; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (365 aa)
crrGlucose-specific enzyme IIA component of PTS; Function experimentally demonstrated in the studied species; transporter. (169 aa)
cysZPutative inner membrane protein; High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway; Belongs to the CysZ family. (253 aa)
nupCNucleoside (except guanosine) transporter; Function experimentally demonstrated in the studied species; transporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family. (400 aa)
emrKEmrKY-TolC multidrug resistance efflux pump, membrane fusion protein component; Function experimentally demonstrated in the studied species; transporter. (387 aa)
nuoANADH:ubiquinone oxidoreductase, membrane subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (147 aa)
nuoBNADH:ubiquinone oxidoreductase, chain B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (220 aa)
nuoENADH:ubiquinone oxidoreductase, chain E; Function experimentally demonstrated in the studied species; carrier. (166 aa)
nuoGNADH:ubiquinone oxidoreductase, chain G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (910 aa)
nuoHNADH:ubiquinone oxidoreductase, membrane subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa)
nuoINADH:ubiquinone oxidoreductase, chain I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa)
nuoJNADH:ubiquinone oxidoreductase, membrane subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (184 aa)
nuoKNADH:ubiquinone oxidoreductase, membrane subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
nuoLNADH:ubiquinone oxidoreductase, membrane subunit L; Function experimentally demonstrated in the studied species; membrane component. (613 aa)
nuoMNADH:ubiquinone oxidoreductase, membrane subunit M; Function experimentally demonstrated in the studied species; membrane component. (509 aa)
nuoNNADH:ubiquinone oxidoreductase, membrane subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa)
elaBConserved hypothetical protein; Homologs of previously reported genes of unknown function. (101 aa)
rcsCHybrid sensory kinase in two-component regulatory system with RcsB and YojN; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsC functions as a membrane- associated protein kinase that phosphorylates RcsD in response to environmental signals. The phosphoryl group is then transferred to the response regulator RcsB. (933 aa)
yojIMultidrug/microcin transport system ATP-binding/permease protein; Function experimentally demonstrated in the studied species; transporter. (547 aa)
ccmFHeme lyase, CcmF subunit; Function experimentally demonstrated in the studied species; enzyme. (647 aa)
aqpZAquaporin; Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity; Belongs to the MIP/aquaporin (TC 1.A.8) family. (231 aa)
macAMacrolide transporter subunit, membrane fusion protein (MFP) component; Function experimentally demonstrated in the studied species; transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (371 aa)
macBFused macrolide transporter subunits of ABC superfamily: ATP-binding component; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (648 aa)
cydCFused cysteine transporter subunits of ABC superfamily: membrane component; Function experimentally demonstrated in the studied species; transporter. (573 aa)
cydDFused cysteine transporter subunits of ABC superfamily: membrane component; Function experimentally demonstrated in the studied species; transporter. (588 aa)
ftsKDNA-binding membrane protein required for chromosome resolution and partitioning; Function experimentally demonstrated in the studied species; cell process. (1368 aa)
focAFormate transporter; Function experimentally demonstrated in the studied species; transporter. (285 aa)
msbAFused lipid transporter subunits of ABC superfamily: membrane component; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation. (582 aa)
ompFOuter membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (357 aa)
pqiAParaquat-inducible membrane protein A; Function experimentally demonstrated in the studied species; cell process. (417 aa)
ompAOuter membrane protein A (3a;II*;G;d); Function experimentally demonstrated in the studied species; membrane component; Belongs to the outer membrane OOP (TC 1.B.6) superfamily. (374 aa)
yccAConserved hypothetical protein; Homologs of previously reported genes of unknown function; membrane component; Belongs to the BI1 family. (219 aa)
hyaCHydrogenase 1, b-type cytochrome subunit; Function experimentally demonstrated in the studied species; carrier. (235 aa)
putPProline:sodium symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (502 aa)
efeUFerrous iron permease; Function of homologous gene experimentally demonstrated in an other organism; transporter. (279 aa)
efeOFerrous iron transport binding protein; Function experimentally demonstrated in the studied species; transporter. (375 aa)
pgaAPutative outer membrane protein associated with biofilm formation; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (807 aa)
csgGPutative outer membrane lipoprotein involved in curli production assembly/transport; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; lipoprotein. (277 aa)
csgFPutative transport/assembly protein for curli synthesis; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component. (138 aa)
csgEPutative transport/assembly protein for curli synthesis; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (129 aa)
mdoHGlucan biosynthesis: glycosyl transferase; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (847 aa)
mdtGPutative metabolite efflux transporter; Confers resistance to fosfomycin and deoxycholate. Belongs to the major facilitator superfamily. DHA1 family. MdtG (TC 2.A.1.2.20) subfamily. (408 aa)
mviNConserved hypothetical protein; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (511 aa)
ptsGFragment of ferric-rhodotorulic acid outer membrane transporter (part 2); Gene remnant; transporter. (477 aa)
lolCOuter membrane-specific lipoprotein transporter subunit; Function experimentally demonstrated in the studied species; transporter. (399 aa)
potCPolyamine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (264 aa)
potBPolyamine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (275 aa)
potAPolyamine transporter subunit; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (378 aa)
CAR18103.1Putative side tail fiber protein homolog from lambdoid prophage; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (686 aa)
CAR18056.1Conserved hypothetical protein, putative side tail fiber protein homolog from prophage; Homologs of previously reported genes of unknown function. (801 aa)
CAR18054.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (234 aa)
sitDIron transport protein, inner membrane component; Function of strongly homologous gene; membrane component. (285 aa)
sitCIron transport protein, inner membrane component; Function of strongly homologous gene; membrane component. (285 aa)
sitBIron transport protein, ATP-binding component; Function of strongly homologous gene; membrane component. (275 aa)
dsbBOxidoreductase that catalyzes reoxidation of DsbA protein disulfide isomerase I; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (176 aa)
CAR17984.1Conserved hypothetical protein, putative side tail fiber protein homolog from prophage; Homologs of previously reported genes of unknown function. (801 aa)
CAR17982.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (217 aa)
eamACysteine and O-acetyl-L-serine efflux system; Function experimentally demonstrated in the studied species; transporter. (299 aa)
CAR17961.1Putative carbohydrate-specific outer membrane porin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (557 aa)
lsrBFragment of AI2 transporter; Gene remnant; transporter. (340 aa)
CAR17896.1Conserved hypothetical protein; Connects the signal transduction between the two-component systems EvgS/EvgA and PhoQ/PhoP, by directly interacting with PhoQ and thus activating the PhoQ/PhoP system, in response to acid stress conditions; Belongs to the SafA family. (65 aa)
yddBPutative porin protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (790 aa)
fdnIFormate dehydrogenase-N, cytochrome B556 (gamma) subunit, nitrate-inducible; Function experimentally demonstrated in the studied species; carrier. (217 aa)
fdnHFormate dehydrogenase-N, Fe-S (beta) subunit, nitrate-inducible; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (294 aa)
yddGMetabolite and drug efflux pump; Function of homologous gene experimentally demonstrated in an other organism; transporter. (274 aa)
CAR17865.1Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family. (366 aa)
ydaNPutative divalent cation transporter; Mediates efflux of zinc ions; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family. (327 aa)
ompGOuter membrane porin; Function experimentally demonstrated in the studied species; transporter. (301 aa)
ycjVPutative sugar transporter subunit: ATP-binding component of ABC superfamily transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the ABC transporter superfamily. (360 aa)
CAR17764.1Putative efflux protein, membrane fusion (MFP) family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (383 aa)
yciSConserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Belongs to the LapA family. (102 aa)
pgpBFunction experimentally demonstrated in the studied species; enzyme. (254 aa)
yciBPutative intracellular septation protein involved in cell division; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (179 aa)
tonBMembrane spanning protein in TonB-ExbB-ExbD complex; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (255 aa)
narINitrate reductase 1, gamma (cytochrome b(NR)) subunit; Function experimentally demonstrated in the studied species; carrier. (225 aa)
narHNitrate reductase 1, beta (Fe-S) subunit; Function experimentally demonstrated in the studied species; carrier. (512 aa)
narGNitrate reductase 1, alpha subunit; Function experimentally demonstrated in the studied species; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (1247 aa)
narKNitrate/nitrite transporter; Function experimentally demonstrated in the studied species; transporter. (463 aa)
CAR17664.1Putative ABC transporter periplasmic binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (354 aa)
clcBPutative voltage-gated chloride channel; Probably acts as an electrical shunt for an outwardly- directed proton pump that is linked to amino acid decarboxylation, as part of the extreme acid resistance (XAR) response; Belongs to the chloride channel (TC 2.A.49) family. ClcB subfamily. (418 aa)
pntBPyridine nucleotide transhydrogenase, beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa)
pntAPyridine nucleotide transhydrogenase, alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. (510 aa)
blrBeta-lactam resistance membrane protein; Function experimentally demonstrated in the studied species; membrane component. (66 aa)
ydgRPutative oligopeptide transporter; Proton-dependent permease that transports di- and tripeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpA subfamily. (500 aa)
ydiSPutative oxidoreductase subunit with FAD/NAD(P)-binding domain; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (429 aa)
ydiTPutative 4Fe-4S ferredoxin-type oxidoreductase subunit; Could be a 3Fe-4S cluster-containing protein. (97 aa)
btuDVitamin B12 transporter subunit : ATP-binding component of ABC superfamily; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Responsible for energy coupling to the transport system. (249 aa)
btuCVitamin B12 transporter subunit: membrane component of ABC superfamily; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane. (326 aa)
ynjDPutative sulfate/thiosulfate ABC transporter ATP-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (217 aa)
sppAProtease IV (signal peptide peptidase); Function experimentally demonstrated in the studied species; enzyme. (618 aa)
manXFused mannose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter. (323 aa)
manYMannose-specific enzyme IIC component of PTS; Function experimentally demonstrated in the studied species; transporter. (266 aa)
manZMannose-specific enzyme IID component of PTS; Function experimentally demonstrated in the studied species; transporter. (286 aa)
htpXMembrane-associated Zn-dependent endopeptidase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase M48B family. (293 aa)
yebSConserved hypothetical protein; Homologs of previously reported genes of unknown function; putative membrane component. (427 aa)
yebTConserved hypothetical protein; Homologs of previously reported genes of unknown function. (877 aa)
znuCZinc transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family. (251 aa)
motBProtein that enables flagellar motor rotation; Function experimentally demonstrated in the studied species; cell process. (308 aa)
motAFragment of DNA-binding transcriptional dual regulator with FlhD (part 2); Gene remnant; regulator. (295 aa)
araHFused L-arabinose transporter subunits of ABC superfamily: membrane components; Function experimentally demonstrated in the studied species; transporter; Belongs to the binding-protein-dependent transport system permease family. (329 aa)
CAR17225.1Outer membrane protein N precursor (porin); Function of strongly homologous gene; membrane component. (375 aa)
fyuAYersiniabactin/pesticin outer membrane receptor (IRPC); Function of homologous gene experimentally demonstrated in an other organism; receptor. (673 aa)
wcaJPutative UDP-sugar lipid carrier transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (464 aa)
wzcProtein-tyrosine kinase; Function experimentally demonstrated in the studied species; enzyme. (720 aa)
wzaLipoprotein required for capsular polysaccharide translocation through the outer membrane; Function of strongly homologous gene; lipoprotein. (379 aa)
yegKConserved hypothetical protein; Homologs of previously reported genes of unknown function. (253 aa)
mdtAMultidrug efflux system, subunit A; The MdtABC tripartite complex confers resistance against novobiocin and deoxycholate; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (415 aa)
CAR17020.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function; extrachromosomal origin. (686 aa)
yehXPutative transporter subunit: ATP-binding component of ABC superfamily transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (308 aa)
yehZPutative transporter subunit: periplasmic-binding component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (305 aa)
potIPutrescine transporter subunit: membrane component of ABC superfamily; Function experimentally demonstrated in the studied species; transporter. (281 aa)
potHPutrescine transporter subunit: membrane component of ABC superfamily; Function experimentally demonstrated in the studied species; transporter. (317 aa)
potGPutrescine transporter subunit: ATP-binding component of ABC superfamily; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system. (377 aa)
cmrMultidrug efflux system protein; Function experimentally demonstrated in the studied species; transporter. (410 aa)
fiuPutative TonB-dependent iron outer membrane transporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (760 aa)
ybhSPutative transporter subunit: permease component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (377 aa)
ybhRPutative transporter subunit: permease component of ABC superfamily; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (368 aa)
modFFused molybdate transporter subunits of ABC superfamily: ATP-binding components; Function experimentally demonstrated in the studied species; transporter. (490 aa)
tolRMembrane spanning protein in TolA-TolQ-TolR complex; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolQ, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (142 aa)
tolQMembrane spanning protein in TolA-TolQ-TolR complex; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. Required, with TolR, for the proton motive force-dependent activation of TolA and for TolA-Pal interaction. (230 aa)
cydACytochrome d terminal oxidase, subunit I; Function experimentally demonstrated in the studied species; carrier. (522 aa)
ybgHPutative transporter; Probable proton-dependent permease that transports dipeptides; Belongs to the PTR2/POT transporter (TC 2.A.17) family. DtpD subfamily. (493 aa)
kdpAPotassium translocating ATPase, subunit A; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane. (557 aa)
kdpBPotassium translocating ATPase, subunit B; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system. Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IA subfamily. (682 aa)
kdpCPotassium translocating ATPase, subunit C; Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP-binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB/KdpC/ATP ternary complex. (190 aa)
lntApolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (512 aa)
dacAD-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 5); Function experimentally demonstrated in the studied species; enzyme; Belongs to the peptidase S11 family. (403 aa)
crcBConserved hypothetical protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (127 aa)
fepAIron-enterobactin outer membrane transporter; Function experimentally demonstrated in the studied species; transporter. (746 aa)
cusACopper/silver efflux system, membrane component; Function experimentally demonstrated in the studied species; transporter; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1047 aa)
CAR16671.1Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (234 aa)
CAR16669.1Conserved hypothetical protein, putative side tail fiber protein homolog from prophage; Homologs of previously reported genes of unknown function. (801 aa)
nhaASodium-proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (388 aa)
lspAProlipoprotein signal peptidase (signal peptidase II); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (164 aa)
fixCPutative oxidoreductase with FAD/NAD(P)-binding domain; Part of an electron transfer system. Belongs to the ETF-QO/FixC family. (428 aa)
fixXPutative 4Fe-4S ferredoxin; Could be a 3Fe-4S cluster-containing protein. (95 aa)
kefFGlutathione-regulated potassium-efflux system ancillary protein KefF; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily. (176 aa)
kefCPotassium:proton antiporter; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (620 aa)
ftsLMembrane bound cell division protein at septum containing leucine zipper motif; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (121 aa)
ftsWIntegral membrane protein involved in stabilizing FstZ ring during cell division; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (414 aa)
ftsQMembrane anchored protein involved in growth of wall at septum; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (276 aa)
secAPreprotein translocase subunit, ATPase; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (901 aa)
aroPAromatic amino acid transporter; Function experimentally demonstrated in the studied species; transporter. (457 aa)
gcdGlucose dehydrogenase; Function experimentally demonstrated in the studied species; enzyme. (796 aa)
yadIPutative PTS Enzyme IIA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (146 aa)
folK2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function experimentally demonstrated in the studied species; enzyme. (159 aa)
mrcBFused glycosyl transferase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (844 aa)
fhuCIron-hydroxamate transporter subunit; Function experimentally demonstrated in the studied species; transporter. (265 aa)
fhuBFused iron-hydroxamate transporter subunits of ABC superfamily: membrane components; Function experimentally demonstrated in the studied species; transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (660 aa)
btuFVitamin B12 transporter subunit: periplasmic-binding component of ABC superfamily; Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Binds vitamin B12 and delivers it to the periplasmic surface of BtuC. (266 aa)
amtBAmmonium transporter; Function experimentally demonstrated in the studied species; transporter. (428 aa)
ppiDPeptidyl-prolyl cis-trans isomerase (rotamase D); Function experimentally demonstrated in the studied species; enzyme. (623 aa)
cyoCCytochrome o ubiquinol oxidase subunit III; Function experimentally demonstrated in the studied species; carrier. (204 aa)
cyoDCytochrome o ubiquinol oxidase subunit IV; Function experimentally demonstrated in the studied species; carrier. (109 aa)
yajRPutative transporter, major facilitator family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (454 aa)
pgpAPhosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (172 aa)
tsxFragment of putative lipoprotein (partial); Gene remnant; lipoprotein. (294 aa)
yajCSecYEG protein translocase auxillary subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (110 aa)
phoRSensory histidine kinase in two-component regulatory system with PhoB; Function experimentally demonstrated in the studied species; regulator. (431 aa)
sbmATransporter involved in cell envelope modification; Function of homologous gene experimentally demonstrated in an other organism; transporter. (406 aa)
lacYLactose/galactose transporter; Function experimentally demonstrated in the studied species; transporter. (417 aa)
phoEOuter membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (351 aa)
mbhAFlagellar system protein; Function of strongly homologous gene; structure. (261 aa)
metNDL-methionine transporter subunit; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (343 aa)
metIDL-methionine transporter subunit; Function experimentally demonstrated in the studied species; transporter. (217 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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