(6 nodes) Phosphotransferase system, HPr histidine phosphorylation site network (Escherichia coli IAI39)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	dhaH	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family. (472 aa)
	fruB	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter. (376 aa)
	ptsH	Phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr); Function experimentally demonstrated in the studied species; transporter. (85 aa)
	ptsA	Fused putative PTS enzymes: Hpr component; Function of strongly homologous gene; transporter. (833 aa)
	npr	Phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr); Function experimentally demonstrated in the studied species; transporter. (90 aa)
	CAR20080.1	Putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier. (89 aa)

Your Current Organism:

Escherichia coli IAI39

NCBI taxonomy Id: 585057
Other names: E. coli IAI39

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAR20080.1	dhaH	ECIAI39_3968	ECIAI39_1534	Putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family.	0.896
CAR20080.1	fruB	ECIAI39_3968	ECIAI39_2309	Putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter.	0.955
CAR20080.1	ptsA	ECIAI39_3968	ECIAI39_3041	Putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.	Fused putative PTS enzymes: Hpr component; Function of strongly homologous gene; transporter.	0.911
CAR20080.1	ptsH	ECIAI39_3968	ECIAI39_2561	Putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.	Phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr); Function experimentally demonstrated in the studied species; transporter.	0.915
dhaH	CAR20080.1	ECIAI39_1534	ECIAI39_3968	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family.	Putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.	0.896
dhaH	fruB	ECIAI39_1534	ECIAI39_2309	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family.	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter.	0.937
dhaH	npr	ECIAI39_1534	ECIAI39_3701	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family.	Phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr); Function experimentally demonstrated in the studied species; transporter.	0.861
dhaH	ptsA	ECIAI39_1534	ECIAI39_3041	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family.	Fused putative PTS enzymes: Hpr component; Function of strongly homologous gene; transporter.	0.995
dhaH	ptsH	ECIAI39_1534	ECIAI39_2561	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family.	Phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr); Function experimentally demonstrated in the studied species; transporter.	0.876
fruB	CAR20080.1	ECIAI39_2309	ECIAI39_3968	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter.	Putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.	0.955
fruB	dhaH	ECIAI39_2309	ECIAI39_1534	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter.	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family.	0.937
fruB	npr	ECIAI39_2309	ECIAI39_3701	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter.	Phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr); Function experimentally demonstrated in the studied species; transporter.	0.489
fruB	ptsA	ECIAI39_2309	ECIAI39_3041	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter.	Fused putative PTS enzymes: Hpr component; Function of strongly homologous gene; transporter.	0.991
fruB	ptsH	ECIAI39_2309	ECIAI39_2561	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter.	Phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr); Function experimentally demonstrated in the studied species; transporter.	0.930
npr	dhaH	ECIAI39_3701	ECIAI39_1534	Phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr); Function experimentally demonstrated in the studied species; transporter.	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family.	0.861
npr	fruB	ECIAI39_3701	ECIAI39_2309	Phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr); Function experimentally demonstrated in the studied species; transporter.	Fused fructose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter.	0.489
npr	ptsA	ECIAI39_3701	ECIAI39_3041	Phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr); Function experimentally demonstrated in the studied species; transporter.	Fused putative PTS enzymes: Hpr component; Function of strongly homologous gene; transporter.	0.880
npr	ptsH	ECIAI39_3701	ECIAI39_2561	Phosphohistidinoprotein-hexose phosphotransferase component of N-regulated PTS system (Npr); Function experimentally demonstrated in the studied species; transporter.	Phosphohistidinoprotein-hexose phosphotransferase component of PTS system (Hpr); Function experimentally demonstrated in the studied species; transporter.	0.690
ptsA	CAR20080.1	ECIAI39_3041	ECIAI39_3968	Fused putative PTS enzymes: Hpr component; Function of strongly homologous gene; transporter.	Putative phosphocarrier HPr protein of a carbohydrate phosphotransferase system; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.	0.911
ptsA	dhaH	ECIAI39_3041	ECIAI39_1534	Fused putative PTS enzymes: Hpr component; Function of strongly homologous gene; transporter.	Fused dihydroxyacetone-specific PTS enzymes: HPr component; Function experimentally demonstrated in the studied species; enzyme; Belongs to the PEP-utilizing enzyme family.	0.995