(8 nodes) Toll Like Receptor TLR6:TLR2 Cascade network (Escherichia coli IAI39)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAR17225.1	Outer membrane protein N precursor (porin); Function of strongly homologous gene; membrane component. (375 aa)
	fklB	FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase); Function experimentally demonstrated in the studied species; enzyme. (206 aa)
	CAR17865.1	Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family. (366 aa)
	ompN	Outer membrane pore protein N, non-specific; Function experimentally demonstrated in the studied species; transporter. (377 aa)
	phoE	Outer membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (351 aa)
	fkpA	FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase); Function experimentally demonstrated in the studied species; enzyme. (270 aa)
	ompC	Outer membrane porin protein C; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (364 aa)
	ompF	Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family. (357 aa)

Your Current Organism:

Escherichia coli IAI39

NCBI taxonomy Id: 585057
Other names: E. coli IAI39

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAR17225.1	ompF	ECIAI39_1091	ECIAI39_2218	Outer membrane protein N precursor (porin); Function of strongly homologous gene; membrane component.	Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.904
CAR17865.1	ompC	ECIAI39_1734	ECIAI39_2352	Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family.	Outer membrane porin protein C; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.579
CAR17865.1	ompF	ECIAI39_1734	ECIAI39_2218	Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family.	Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.605
CAR17865.1	phoE	ECIAI39_1734	ECIAI39_0410	Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family.	Outer membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.554
ompC	CAR17865.1	ECIAI39_2352	ECIAI39_1734	Outer membrane porin protein C; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family.	0.579
ompC	ompF	ECIAI39_2352	ECIAI39_2218	Outer membrane porin protein C; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.980
ompC	phoE	ECIAI39_2352	ECIAI39_0410	Outer membrane porin protein C; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.891
ompF	CAR17225.1	ECIAI39_2218	ECIAI39_1091	Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane protein N precursor (porin); Function of strongly homologous gene; membrane component.	0.904
ompF	CAR17865.1	ECIAI39_2218	ECIAI39_1734	Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family.	0.605
ompF	ompC	ECIAI39_2218	ECIAI39_2352	Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane porin protein C; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.980
ompF	phoE	ECIAI39_2218	ECIAI39_0410	Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.917
phoE	CAR17865.1	ECIAI39_0410	ECIAI39_1734	Outer membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane porin protein ompD precursor; Function of homologous gene experimentally demonstrated in an other organism; membrane component; Belongs to the Gram-negative porin family.	0.554
phoE	ompC	ECIAI39_0410	ECIAI39_2352	Outer membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane porin protein C; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.891
phoE	ompF	ECIAI39_0410	ECIAI39_2218	Outer membrane phosphoporin protein E; Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	Outer membrane porin 1a (Ia;b;F); Function experimentally demonstrated in the studied species; transporter; Belongs to the Gram-negative porin family.	0.917