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mak mak fbaB fbaB gmd gmd fcl fcl cpsB cpsB cpsG cpsG manC manC cpsG-2 cpsG-2 yedP yedP manZ manZ manY manY manX manX yniC yniC pfkB pfkB manA manA fruA fruA fruK fruK yfaU yfaU yfbT yfbT srlA srlA srlE srlE srlB srlB srlD srlD CAR19082.1 CAR19082.1 glpX glpX tpiA tpiA pfkA pfkA rhaB rhaB rhaA rhaA rhaD rhaD fucA fucA fucI fucI fucK fucK fbaA fbaA yggF yggF yggP yggP cmtA cmtA cmtB cmtB xylA xylA mtlA mtlA mtlD mtlD CAR20286.1 CAR20286.1 CAR20287.1 CAR20287.1 CAR20288.1 CAR20288.1 CAR20289.1 CAR20289.1 CAR20290.1 CAR20290.1 CAR20291.1 CAR20291.1 CAR20518.1 CAR20518.1 CAR20519.1 CAR20519.1 CAR20520.1 CAR20520.1 CAR20521.1 CAR20521.1 CAR20522.1 CAR20522.1 CAR20523.1 CAR20523.1 alsK alsK alsE alsE rpiB rpiB fbp fbp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
makManno(fructo)kinase; Function experimentally demonstrated in the studied species; enzyme. (302 aa)
fbaBFructose-bisphosphate aldolase class I; Function experimentally demonstrated in the studied species; enzyme. (350 aa)
gmdGDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (321 aa)
cpsBMannose-1-phosphate guanyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family. (478 aa)
cpsGPhosphomannomutase; Function experimentally demonstrated in the studied species; enzyme. (456 aa)
manCMannose-1-phosphate guanylyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family. (474 aa)
cpsG-2Phosphomannomutase; Function experimentally demonstrated in the studied species; enzyme. (454 aa)
yedPPutative mannosyl-3-phosphoglycerate phosphatase (mngB-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (271 aa)
manZMannose-specific enzyme IID component of PTS; Function experimentally demonstrated in the studied species; transporter. (286 aa)
manYMannose-specific enzyme IIC component of PTS; Function experimentally demonstrated in the studied species; transporter. (266 aa)
manXFused mannose-specific PTS enzymes: IIA component; Function experimentally demonstrated in the studied species; transporter. (323 aa)
yniCPutative phosphoglycolate phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (222 aa)
pfkB6-phosphofructokinase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family. (309 aa)
manAMannose-6-phosphate isomerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the mannose-6-phosphate isomerase type 1 family. (391 aa)
fruAFused fructose-specific PTS enzymes: IIBcomponent; Function experimentally demonstrated in the studied species; transporter. (563 aa)
fruKFructose-1-phosphate kinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family. (312 aa)
yfaUPutative 2,4-dihydroxyhept-2-ene-1,7-dioic acid-like aldolase; Catalyzes the reversible retro-aldol cleavage of 2-keto-3- deoxy-L-rhamnonate (KDR) to pyruvate and lactaldehyde. Belongs to the HpcH/HpaI aldolase family. KDR aldolase subfamily. (267 aa)
yfbTPutative phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (216 aa)
srlAGlucitol/sorbitol-specific enzyme IIC component of PTS; Function experimentally demonstrated in the studied species; transporter. (187 aa)
srlEGlucitol/sorbitol-specific enzyme IIB component of PTS; Function experimentally demonstrated in the studied species; transporter. (319 aa)
srlBGlucitol/sorbitol-specific enzyme IIA component of PTS; Function experimentally demonstrated in the studied species; transporter. (123 aa)
srlDSorbitol-6-phosphate dehydrogenase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (259 aa)
CAR19082.1Fructokinase; Function of strongly homologous gene; enzyme; Belongs to the carbohydrate kinase PfkB family. (306 aa)
glpXFructose 1,6-bisphosphatase II; Function experimentally demonstrated in the studied species; enzyme. (336 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (255 aa)
pfkA6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
rhaBRhamnulokinase; Involved in the catabolism of L-rhamnose (6-deoxy-L-mannose). Catalyzes the transfer of the gamma-phosphate group from ATP to the 1- hydroxyl group of L-rhamnulose to yield L-rhamnulose 1-phosphate. (489 aa)
rhaAL-rhamnose isomerase; Function experimentally demonstrated in the studied species; enzyme. (419 aa)
rhaDRhamnulose-1-phosphate aldolase; Catalyzes the reversible cleavage of L-rhamnulose-1-phosphate to dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. Belongs to the aldolase class II family. RhaD subfamily. (274 aa)
fucAL-fuculose-1-phosphate aldolase; Involved in the degradation of L-fucose and D-arabinose. Catalyzes the reversible cleavage of L-fuculose 1-phosphate (Fuc1P) to yield dihydroxyacetone phosphate (DHAP) and L-lactaldehyde. (215 aa)
fucIL-fucose isomerase; Converts the aldose L-fucose into the corresponding ketose L- fuculose. (591 aa)
fucKL-fuculokinase; Catalyzes the phosphorylation of L-fuculose. Belongs to the FGGY kinase family. (482 aa)
fbaAFructose-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
yggFPutative hexoseP phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (321 aa)
yggPPutative dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (425 aa)
cmtAFused mannitol-specific PTS enzymes: IIB component; Function of strongly homologous gene; transporter. (462 aa)
cmtBPutative mannitol-specific enzyme IIA component of PTS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (147 aa)
xylAD-xylose isomerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the xylose isomerase family. (440 aa)
mtlAFused mannitol-specific PTS enzymes: IIA components; Function experimentally demonstrated in the studied species; transporter. (637 aa)
mtlDMannitol-1-phosphate dehydrogenase, NAD(P)-binding; Function experimentally demonstrated in the studied species; enzyme. (382 aa)
CAR20286.1Putative sugar kinase/transcriptional regulator. ATPase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (321 aa)
CAR20287.1Putative fructose-bisphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (286 aa)
CAR20288.1Putative sugar aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (283 aa)
CAR20289.1Putative phosphotransferase system, fructose-specific IIC component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (363 aa)
CAR20290.1Putative phosphotransferase system, fructose-specific IIB subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (104 aa)
CAR20291.1Putative phosphotransferase system (PTS), fructose-specific IIA component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (156 aa)
CAR20518.1L-sorbose 1-phosphate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (413 aa)
CAR20519.1Sorbose permease IID component; Function of homologous gene experimentally demonstrated in an other organism; transporter. (284 aa)
CAR20520.1Sorbose permease IIC component (PTS system); Function of homologous gene experimentally demonstrated in an other organism; transporter. (265 aa)
CAR20521.1Sorbose-specific phosphotransferase enzyme IIB component (PTS system); Function of homologous gene experimentally demonstrated in an other organism; transporter. (164 aa)
CAR20522.1Sorbose-specific phosphotransferase enzyme IIA component (PTS system); Function of homologous gene experimentally demonstrated in an other organism; transporter. (135 aa)
CAR20523.1Sorbitol-6-phosphate 2-dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (268 aa)
alsKD-allose kinase; Catalyzes the phosphorylation of D-allose to D-allose 6- phosphate. (309 aa)
alsEAllulose-6-phosphate 3-epimerase; Function experimentally demonstrated in the studied species; enzyme. (231 aa)
rpiBRibose 5-phosphate isomerase B/allose 6-phosphate isomerase; Function experimentally demonstrated in the studied species; enzyme. (149 aa)
fbpFragment of putative sugar transporter subunit: membrane component of ABC superfamily (part 2); Gene remnant; putative transporter. (332 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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