STRINGSTRING
malZ malZ lacZ lacZ pgm pgm galM galM galK galK galT galT galE galE gatY gatY gatZ gatZ gatA gatA gatB gatB gatC gatC gatD gatD galF galF pfkB pfkB galU galU CAR18496.1 CAR18496.1 glk glk CAR19085.1 CAR19085.1 pfkA pfkA yihR yihR CAR19284.1 CAR19284.1 ebgA ebgA ebgC ebgC kbaZ kbaZ agaV agaV CAR19749.1 CAR19749.1 CAR19750.1 CAR19750.1 CAR19751.1 CAR19751.1 agaA agaA kbaY kbaY agaB agaB agaC agaC agaD agaD agaI agaI CAR19865.1 CAR19865.1 GatY GatY CAR19871.1 CAR19871.1 CAR20076.1 CAR20076.1 CAR20077.1 CAR20077.1 CAR20078.1 CAR20078.1 GatY-2 GatY-2 dgoD dgoD dgoA dgoA dgoK dgoK melA melA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
malZMaltodextrin glucosidase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycosyl hydrolase 13 family. (605 aa)
lacZbeta-D-galactosidase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the glycosyl hydrolase 2 family. (1024 aa)
pgmPhosphoglucomutase; Function experimentally demonstrated in the studied species; enzyme. (546 aa)
galMGalactose-1-epimerase (mutarotase); Converts alpha-aldose to the beta-anomer. (346 aa)
galKGalactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D- galactose to form alpha-D-galactose-1-phosphate (Gal-1-P). Belongs to the GHMP kinase family. GalK subfamily. (382 aa)
galTGalactose-1-phosphate uridylyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the galactose-1-phosphate uridylyltransferase type 1 family. (348 aa)
galEUDP-galactose-4-epimerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
gatYD-tagatose 1,6-bisphosphate aldolase 2, catalytic subunit; Catalytic subunit of the tagatose-1,6-bisphosphate aldolase GatYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires GatZ subunit for full activity and stability. Is involved in the catabolism of galactitol. (284 aa)
gatZD-tagatose 1,6-bisphosphate aldolase 2, subunit; Component of the tagatose-1,6-bisphosphate aldolase GatYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of GatY. When expressed alone, GatZ does not show any aldolase activity. Is involved in the catabolism of galactitol. (420 aa)
gatAGalactitol-specific enzyme IIA component of PTS; Function experimentally demonstrated in the studied species; transporter. (150 aa)
gatBGalactitol-specific enzyme IIB component of PTS; Function experimentally demonstrated in the studied species; transporter. (94 aa)
gatCGalactitol-specific enzyme IIC component of PTS; Function experimentally demonstrated in the studied species; transporter. (451 aa)
gatDGalactitol-1-phosphate dehydrogenase, Zn-dependent and NAD(P)-binding; Function experimentally demonstrated in the studied species; enzyme. (346 aa)
galFPutative subunit with GalU; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (297 aa)
pfkB6-phosphofructokinase II; Function experimentally demonstrated in the studied species; enzyme; Belongs to the carbohydrate kinase PfkB family. (309 aa)
galUGlucose-1-phosphate uridylyltransferase; Function experimentally demonstrated in the studied species; enzyme. (302 aa)
CAR18496.1Mandelate racemase/muconate lactonizing enzyme family protein. (404 aa)
glkGlucokinase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the bacterial glucokinase family. (321 aa)
CAR19085.1Sucrose-6-phosphate hydrolase (Sucrase) (Invertase); Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. (469 aa)
pfkA6-phosphofructokinase I; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (320 aa)
yihRPutative aldose-1-epimerase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (303 aa)
CAR19284.1Acidic carbohydrate kinase; Function of strongly homologous gene; enzyme. (334 aa)
ebgACryptic beta-D-galactosidase, alpha subunit; Function experimentally demonstrated in the studied species; enzyme. (1030 aa)
ebgCCryptic beta-D-galactosidase, beta subunit; Function experimentally demonstrated in the studied species; enzyme. (149 aa)
kbaZTagatose 6-phosphate aldolase 1, kbaZ subunit; Component of the tagatose-1,6-bisphosphate aldolase KbaYZ that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of KbaY. When expressed alone, KbaZ does not show any aldolase activity. (426 aa)
agaVN-acetylgalactosamine-specific enzyme IIB component of PTS; Function experimentally demonstrated in the studied species; transporter. (157 aa)
CAR19749.1Putative enzyme IIC component of PTS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (259 aa)
CAR19750.1Putative hexose/hexosamine family PTS permease IID component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (294 aa)
CAR19751.1N-acetylgalactosamine PTS system EIIA component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (144 aa)
agaAN-acetylglucosamine-6-phosphate deacetylase (GlcNAc 6-P deacetylase); Function of strongly homologous gene; enzyme. (384 aa)
kbaYTagatose 6-phosphate aldolase 1, kbaY subunit; Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6-bisphosphate (TBP). Requires KbaZ subunit for full activity and stability. (286 aa)
agaBN-acetylgalactosamine-specific enzyme IIB component of PTS; Function experimentally demonstrated in the studied species; transporter. (158 aa)
agaCN-acetylgalactosamine-specific enzyme IIC component of PTS; Function experimentally demonstrated in the studied species; transporter. (267 aa)
agaDN-acetylgalactosamine-specific enzyme IID component of PTS; Function experimentally demonstrated in the studied species; transporter. (263 aa)
agaIGalactosamine-6-phosphate isomerase; Function experimentally demonstrated in the studied species; enzyme. (255 aa)
CAR19865.1Putative carbohydrate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (320 aa)
GatYPutative fructose/tagatose biphosphate aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (284 aa)
CAR19871.1Putative pfkB family carbohydrate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (336 aa)
CAR20076.1Putative phosphotransferase system enzyme subunit IIA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (157 aa)
CAR20077.1Putative phosphotransferase system enzyme IIB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (93 aa)
CAR20078.1Putative phosphotransferase system permease component IIC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (462 aa)
GatY-2Putative aldolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (286 aa)
dgoDGalactonate dehydratase; Catalyzes the dehydration of D-galactonate to 2-keto-3-deoxy- D-galactonate. (382 aa)
dgoA2-oxo-3-deoxygalactonate 6-phosphate aldolase; Function experimentally demonstrated in the studied species; enzyme. (205 aa)
dgoK2-oxo-3-deoxygalactonate kinase; Function experimentally demonstrated in the studied species; enzyme. (292 aa)
melAAlpha-galactosidase, NAD(P)-binding; Function experimentally demonstrated in the studied species; enzyme. (451 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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