STRINGSTRING
galE galE gmd gmd fcl fcl cpsB cpsB cpsG cpsG galF galF rmlB rmlB rmlD rmlD rmlA rmlA rmlC rmlC vioA vioA vioB vioB manC manC cpsG-2 cpsG-2 ugd ugd manA manA galU galU rffA rffA rffC rffC rffH rffH rffG rffG rffD rffD rffE rffE neuC neuC neuA neuA neuB neuB glmU glmU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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galEUDP-galactose-4-epimerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (338 aa)
gmdGDP-D-mannose dehydratase, NAD(P)-binding; Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6- deoxy-D-mannose. (373 aa)
fclGDP-L-fucose synthase; Catalyzes the two-step NADP-dependent conversion of GDP-4- dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction. (321 aa)
cpsBMannose-1-phosphate guanyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family. (478 aa)
cpsGPhosphomannomutase; Function experimentally demonstrated in the studied species; enzyme. (456 aa)
galFPutative subunit with GalU; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (297 aa)
rmlBdTDP-glucose 4,6 dehydratase, NAD(P)-binding; Function experimentally demonstrated in the studied species; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (361 aa)
rmlDdTDP-4-dehydrorhamnose reductase subunit, NAD(P)-binding, of dTDP-L-rhamnose synthase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (299 aa)
rmlAGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (292 aa)
rmlCdTDP-6-deoxy-D-glucose-3,5 epimerase; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (181 aa)
vioAdTDP-6-deoxy-D-xylo-4-hexulose aminotransferase (viosamine synthase); Function experimentally demonstrated in the studied species; enzyme; Belongs to the DegT/DnrJ/EryC1 family. (370 aa)
vioBdTDP-viosamine N-acetyltransferase; Function experimentally demonstrated in the studied species; enzyme. (192 aa)
manCMannose-1-phosphate guanylyltransferase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family. (474 aa)
cpsG-2Phosphomannomutase; Function experimentally demonstrated in the studied species; enzyme. (454 aa)
ugdUDP-glucose 6-dehydrogenase; Function experimentally demonstrated in the studied species; enzyme. (388 aa)
manAMannose-6-phosphate isomerase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the mannose-6-phosphate isomerase type 1 family. (391 aa)
galUGlucose-1-phosphate uridylyltransferase; Function experimentally demonstrated in the studied species; enzyme. (302 aa)
rffATDP-4-oxo-6-deoxy-D-glucose transaminase; Catalyzes the synthesis of dTDP-4-amino-4,6-dideoxy-D- galactose (dTDP-Fuc4N) from dTDP-4-keto-6-deoxy-D-glucose (dTDP-D- Glc4O) and L-glutamate; Belongs to the DegT/DnrJ/EryC1 family. (376 aa)
rffCTDP-fucosamine acetyltransferase; Catalyzes the acetylation of dTDP-fucosamine (dTDP-4-amino- 4,6-dideoxy-D-galactose) to dTDP-Fuc4NAc, which is utilized in the biosynthesis of the enterobacterial common antigen (ECA). Belongs to the WecD family. (224 aa)
rffHGlucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (293 aa)
rffGdTDP-glucose 4,6-dehydratase; Function experimentally demonstrated in the studied species; enzyme; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (355 aa)
rffDUDP-N-acetyl-D-mannosaminuronic acid dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa)
rffEUDP-N-acetyl glucosamine-2-epimerase; Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP- N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues. (376 aa)
neuCUDP-N-acetylglucosamine 2-epimerase; Function experimentally demonstrated in the studied species; enzyme. (391 aa)
neuAN-acylneuraminate cytidylyltransferase; Function experimentally demonstrated in the studied species; enzyme. (418 aa)
neuBN-acylneuraminate-9-phosphate synthase; Function experimentally demonstrated in the studied species; enzyme. (346 aa)
glmUFused N-acetyl glucosamine-1-phosphate uridyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (456 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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