STRINGSTRING
dnaE dnaE dnaX dnaX xseB xseB dnaQ dnaQ CAR16649.1 CAR16649.1 holA holA sbcB sbcB exoX exoX holE holE holB holB ligA ligA xseA xseA mutS mutS uvrD uvrD mutH mutH recJ recJ dam dam ligB ligB dnaN dnaN ssb ssb mutL mutL holC holC holD holD
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaEDNA polymerase III alpha subunit; Function experimentally demonstrated in the studied species; enzyme. (1160 aa)
dnaXDNA polymerase III/DNA elongation factor III, tau and gamma subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (643 aa)
xseBExonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (80 aa)
dnaQDNA polymerase III epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (243 aa)
CAR16649.1Putative single-stranded DNA-binding protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin. (149 aa)
holADNA polymerase III, delta subunit; Function experimentally demonstrated in the studied species; enzyme. (343 aa)
sbcBFunction experimentally demonstrated in the studied species; enzyme. (475 aa)
exoXDNA exonuclease X; Function experimentally demonstrated in the studied species; enzyme. (220 aa)
holEDNA polymerase III, theta subunit; Function experimentally demonstrated in the studied species; enzyme. (76 aa)
holBDNA polymerase III, delta prime subunit; Function experimentally demonstrated in the studied species; enzyme. (334 aa)
ligADNA ligase, NAD(+)-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (671 aa)
xseAExonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (455 aa)
mutSMethyl-directed mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (853 aa)
uvrDDNA-dependent ATPase I and helicase II; Function experimentally demonstrated in the studied species; enzyme. (720 aa)
mutHMethyl-directed mismatch repair protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family. (229 aa)
recJssDNA exonuclease, 5'--> 3'-specific; Function experimentally demonstrated in the studied species; enzyme. (577 aa)
damDNA adenine methylase; Function experimentally demonstrated in the studied species; enzyme. (278 aa)
ligBDNA ligase, NAD(+)-dependent; Catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. Belongs to the NAD-dependent DNA ligase family. LigB subfamily. (560 aa)
dnaNDNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)
ssbSingle-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. (178 aa)
mutLMethyl-directed mismatch repair protein; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (616 aa)
holCDNA polymerase III, chi subunit; Function experimentally demonstrated in the studied species; enzyme. (147 aa)
holDDNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown. (137 aa)
Your Current Organism:
Escherichia coli IAI39
NCBI taxonomy Id: 585057
Other names: E. coli IAI39
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