STRINGSTRING
hemE hemE AII45256.1 AII45256.1 acsF acsF AII45365.1 AII45365.1 hemA hemA ccsA ccsA AII45390.1 AII45390.1 AII45521.1 AII45521.1 AII45675.1 AII45675.1 AII45801.1 AII45801.1 AII46071.1 AII46071.1 ccsB ccsB AII46261.1 AII46261.1 AII46332.1 AII46332.1 AII46450.1 AII46450.1 AII46520.1 AII46520.1 AII46675.1 AII46675.1 AII46775.1 AII46775.1 hemF hemF AII47039.1 AII47039.1 hemL hemL hemC hemC hemH hemH AII47271.1 AII47271.1 chlL chlL chlB chlB chlN chlN AII47343.1 AII47343.1 AII47416.1 AII47416.1 AII47417.1 AII47417.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (352 aa)
AII45256.1Membrane protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (190 aa)
acsFMagnesium-protoporphyrin IX monomethyl ester cyclase; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (353 aa)
AII45365.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (331 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (435 aa)
ccsACytochrome C biogenesis protein; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. (298 aa)
AII45390.1Geranylgeranyl diphosphate reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (458 aa)
AII45521.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (342 aa)
AII45675.1Magnesium chelatase; Catalyzes the formation of Mg-protoporphyrin IX from protoporphyrin IX and Mg(2+); first committed step of chlorophyll biosynthesis; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1336 aa)
AII45801.1Magnesium chelatase; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (362 aa)
AII46071.1Cytochrome C biogenesis protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (206 aa)
ccsBCytochrome C biogenesis protein CcsB; Required during biogenesis of c-type cytochromes (cytochrome c6 and cytochrome f) at the step of heme attachment. (422 aa)
AII46261.1uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (265 aa)
AII46332.1SAM-dependent methlyltransferase; Catalyzes the formation of Mg-protoporphyrin IX methyl ester and S-adenosyl-L-homocysteine from Mg-protoporphyrin IX and S-adenosyl-L-methionine; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (237 aa)
AII46450.1Light dependent protochlorophyllide oxido-reductase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (301 aa)
AII46520.1uroporphyrin-III C-methyltransferase; Catalyzes 2 sequential methylations, the formation of precorrin-1 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and uroporphyrin III, and the formation of precorrin-2 and S-adenosyl-L-homocysteine from S-adenosyl-L-methionine and precorrin-1; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (262 aa)
AII46675.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (307 aa)
AII46775.1Magnesium-chelatase subunit ChlD; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (696 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. (365 aa)
AII47039.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ALAD family. (333 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (428 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (317 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (391 aa)
AII47271.1Protochlorophyllide oxidoreductase; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). (316 aa)
chlLProtochlorophyllide reductase; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (296 aa)
chlBLight-independent protochlorophyllide reductase subunit B; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (527 aa)
chlNLight-independent protochlorophyllide reductase subunit N; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (425 aa)
AII47343.1Chitin-binding protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (317 aa)
AII47416.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (363 aa)
AII47417.1Hypothetical protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (452 aa)
Your Current Organism:
Synechococcus sp. KORDI49
NCBI taxonomy Id: 585423
Other names: S. sp. KORDI-49, Synechococcus sp. KORDI-49
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