(8 nodes) De novo UMP biosynthetic process network (Synechococcus sp. KORDI49)

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Your Input:
	pyrC	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (353 aa)
	carA	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (390 aa)
	carB	Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1104 aa)
	pyrF	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (243 aa)
	pyrD	Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (400 aa)
	pyrE	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (194 aa)
	pyrB	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (349 aa)
	AII47303.1	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (371 aa)

Your Current Organism:

Synechococcus sp. KORDI49

NCBI taxonomy Id: 585423
Other names: S. sp. KORDI-49, Synechococcus sp. KORDI-49

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AII47303.1	carA	KR49_12965	KR49_03155	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.998
AII47303.1	carB	KR49_12965	KR49_04230	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.998
AII47303.1	pyrB	KR49_12965	KR49_10445	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.913
AII47303.1	pyrC	KR49_12965	KR49_00370	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.	0.969
AII47303.1	pyrD	KR49_12965	KR49_07965	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.	0.820
AII47303.1	pyrE	KR49_12965	KR49_10120	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.792
AII47303.1	pyrF	KR49_12965	KR49_05880	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.792
carA	AII47303.1	KR49_03155	KR49_12965	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.998
carA	carB	KR49_03155	KR49_04230	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.999
carA	pyrB	KR49_03155	KR49_10445	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.998
carA	pyrC	KR49_03155	KR49_00370	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.	0.567
carA	pyrD	KR49_03155	KR49_07965	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.	0.961
carA	pyrE	KR49_03155	KR49_10120	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.945
carA	pyrF	KR49_03155	KR49_05880	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.	0.945
carB	AII47303.1	KR49_04230	KR49_12965	Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.998
carB	carA	KR49_04230	KR49_03155	Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Carbamoyl phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.999
carB	pyrB	KR49_04230	KR49_10445	Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Aspartate carbamoyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.	0.998
carB	pyrC	KR49_04230	KR49_00370	Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.	0.692
carB	pyrD	KR49_04230	KR49_07965	Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.	0.963
carB	pyrE	KR49_04230	KR49_10120	Carbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).	0.951